REUTERS by Julie Steenhuysen Dec. 22, 2014 CHICAGO --For months, Vanderbilt University researcher Dr. James Crowe has been desperately seeking access to the blood of U.S. Ebola survivors, hoping to extract the proteins that helped them overcome the deadly virus for use in new, potent drugs.
Blood samples from patients suspected of having the Ebola virus disease are prepared for transportation to Freetown for testing, at the Port Loko District Hospital September 27, 2014. Credit: Reuters/Christopher Black/WHO/Handout via Reuters
His efforts finally paid off in mid-November with a donation from Dr. Rick Sacra, a University of Massachusetts physician who contracted Ebola while working in Liberia. The donation puts Crowe at the forefront of a new model for fighting the virus...
TIME MAGAZINE by ALexandra Sifferlin Dec. 19, 2014
In 2015, the three Ebola-affected countries will start offering cash payments for families hit by Ebola, as well as survivors having trouble re-acclimating to society out of stigma for the disease.
Dudu Kromah’s husband died from Ebola. She is looking after ten children, many of them orphans including a 3-month-old baby. She has no income.Carly Learson—Carly Learson / UNDP
Every aspect of Guinea, Liberia and Sierra Leone’s societies have taken a hit from Ebola, and the disease has shocked what were once fragile but growing economies....Every aspect of Guinea, Liberia and Sierra Leone’s societies
“We are seeing a backwards slide of development of about 10 years,” says Boaz Paldi, chief of media and advocacy at the United Nations Development Programme (UNDP). “The outlook is not good. We are fearful for these countries.”
Pharmaceuticals and biotechnology-derived products have attracted the greatest public and professional interest in treating victims of Ebola virus disease. But a privately-held, small company with a treatment for shock and multi-organ failure may be the dark horse victor in the race to stop the West African outbreak. LB1148 from San Diego-based Leading BioSciences is starting Phase 2 clinical trials that build on 12 years of NIH-funded research to address an underappreciated, common denominator in shock and organ failure, including shock caused by Ebola infection.
German doctors think they have another possible drug to add to the Ebola treatment pipeline. It's one already shown to be safe and in trials to treat heart attack victims.
The drug, called FX06, is made using a natural human blood-clotting protein called fibrin. The hope is it can help reduce the leaking of blood vessels that can seriously threaten people with advanced Ebola infections.
The team at Frankfurt University Hospital say it may have helped save a Ugandan doctor they treated, although they note it failed to save a second patient.
Nonetheless, it should be tested, they wrote in the Lancet medical journal.
"Even though the patient was critically ill, we were able to support him long enough for his body to start antibody production and for the virus to be cleared by his body's defenses," said Dr. Timo Wolf, who helped lead the research team. "FX06 could potentially be a valuable agent in contribution to supportive therapy."
A front-line report from Sierra Leone examines efforts to change hearts and minds in West Africa’s villages.
NATURE by Erika Check Hayden Dec. 17, 2014
Bombali District, Sierra Leone --Since September, the Ebola virus has stalked the villages and towns along the Kamakwie–Makeni Road, a rutted, red-dirt track that serves as the main artery for a string of villages in the western part of Sierra Leone’s Bombali District.
Yeli Sanda, a village just a few kilometres outside the district’s capital city of Makeni, was the first place to be hit. Over the following months, more than 40 people in the settlement of about 700 became infected; 22 died. In November, the virus infected a woman in Tambiama, about 11 km up the road. A friend who visited her acquired the virus and carried it another 1.5 km to the village of Mayata. She and at least five others there have died.
U.S. NEWS AND WORLD REPORT HEALTH TODAY by Dennis Thompson Dec. 17, 2014
A screening test has identified more than 50 drugs that could be helpful in treating people with Ebola, researchers report.
"These drugs are all approved (by the FDA) so they could be deployed quickly if follow-up research proves that they are effective," said study author Adolfo Garcia-Sastre, director of the Global Health and Emerging Pathogens Institute with the Icahn School of Medicine at Mount Sinai in New York City.
The study was published online Dec. 17 in the journal Emerging Microbes and Infections.
The screening test involves a laboratory-engineered fake Ebola virus. The fake virus contains two proteins from the deadly pathogen, but does not include the infectious genetic material that makes Ebola so dangerous, Garcia-Sastre said.
UNITED NATIONS NEWS CENTRE Dec. 16, 2014 Response workers battling the Ebola outbreak in West Africa will receive “hazard pay” for the first time in Sierra Leone using mobile money because “unless there is a certain element of incentives, or danger pay, it’s very difficult to attract and retain people,” the United Nations Development Programme (UNDP) announced today.
Ambulance depot near an emergency response centre, in Freetown, Sierra Leone. Ambulances and drivers have to be disinfected after each trip carrying suspected Ebola cases. UN Photo/Martine Perret
“One of the most difficult things about tackling the Ebola crisis is in the area of human resources,” said Sudipto Mukerjee, UNDP’s Country Director for Sierra Leone. “You can construct a treatment centre in a couple of months. You can construct a community care centre in two to three weeks. But getting trained people to come and run them has been a major challenge.”
The transition from direct cash to an electronic solution will help to improve overall efficiency, timeliness and security of payments for Ebola response workers, Mr. Mukerjee said.
uk.reuters.com - by Magdalena Mis - December 10, 2014
LONDON (Thomson Reuters Foundation) - Thousands of Ebola survivors with little to no risk of re-infection are critical to controlling the epidemic and training them has the potential to save thousands of lives and decrease the spread of the virus, experts said on Wednesday.
Survivors have developed immunity and are effectively the only people in the world protected from the virus, which could allow them to care for the sick without risking their lives, said experts in the International Journal of Epidemiology.
UNITED NATONS NEWS CENTRE Dec. 15, 2014 The United Nations Economic Commission for Africa (ECA) today recommended that creditors should seriously consider debt cancellation for the countries worst-hit by the Ebola epidemic in West Africa, and also projected that even if those most affected were to register zero economic growth, the impact on Africa as a continent would be minimal.
With the cost of transport and goods going up and sales going down since the Ebola outbreak, vendors in Waterside Market, Monrovia, Liberia, are making no profit to support their families. Photo: UNDP/Morgana Wingard
“Educational systems, rising social stigma, unemployment, and decreased food security are some of the big issues that Ebola-affected countries must deal with,” according to study on the Socio-Economic Impacts of the Ebola Virus Disease (EVD) on Africa released today by the Addis-Ababa based UN regional forum.
In other news, the UN World Health Organization (WHO) announced that nine companies have made 19 submissions of proposed diagnostic tests for Ebola.
For critics who scoff that Europe’s carbon emission reduction goals are unachievable, Germany has become Exhibit No. 1. Since Chancellor Angela Merkel decreed in the wake of the Fukushima Daiichi nuclear accident that Germany would phase out its nuclear power industry, coal use in Germany has been on the rise, and the country’s carbon emissions have remained stubbornly high.
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