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The mission of the Global Health Working Group is to explore and improve current and emerging states of health and human security worldwide.

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This Working Group is focused on exploring current and emerging states of health and human security worldwide.
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Ebola mutations could make some drugs ineffective

BALTIMORE SUN     by Scott Dance                                                   Jan. 20, 2015

In the year since Ebola began spreading across West Africa, the virus has mutated in more than 600 ways that change it slightly from versions studied in labs and used to develop treatments, according to researchers at Fort Detrick. And 10 of the mutations could make some drugs used to treat the virus ineffective, they wrote in research published Tuesday.

The "genomic drift," as the scientists called it, could make agents similar to the experimental drug ZMapp unable to bind to the virus anymore.

While the changes affect only a tiny fraction of Ebola's genome, they offer new lessons about the virus that might not have been learned because of the wide scope of the outbreak, larger than all others combined
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http://www.baltimoresun.com/health/bs-hs-ebola-mutation-20150120-story.html

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UN: African Countries 'Vital' in Fight Against Ebola

VOICE OF AMERICA    by  Jennifer Lazuta                                                         Jan. 20, 2015
DAKAR, SENEGAL—Sub-Saharan African countries have made relatively small, but “vitally important,” contributions towards the fight against Ebola according to the U.N. Mission for Ebola Emergency Response. This includes sending much-needed health care workers and medical supplies, as well as dedicating already-limited resources toward prevention and surveillance measures within their own borders to stop the further spread of the disease.

Health workers accompany a nine-year-old who contracted the Ebola virus to a Monrovia treatment center.

More than 850 doctors and nurses from African countries have been deployed to Guinea, Liberia and Sierra Leone to help bring an end to West Africa’s Ebola outbreak, which has killed more than 8,500 people since it began nearly a year ago.  

African countries also have collectively donated tens of millions of dollars in financial aid and material resources.

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Davos: Western world ‘vulnerable’ to epidemics, warns Ebola expert

BBC  by Joe Miller                                                                                                    Jan. 21, 2015
DAVOS Switzerland -- The Western world is "vulnerable" to epidemics such as Ebola, and must invest more in researching vaccines, a leading scientist has warned.

Prof Peter Piot told the BBC that developed nations would be in "deep trouble" if they failed to adequately prepare for another outbreak.

Speaking at the World Economic Forum, in Davos, he urged global leaders to take a "long-term view". Public health policies must "transcend politics and borders", he said.

The threat of Ebola, and other infectious diseases such as influenza and Sars, are set to be discussed in Switzerland this week, as politicians and business leaders from around the globe gather for the annual WEF.

Read complete story.

http://www.bbc.com/news/business-30907630

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Ebola Fight Needs $1 Billion More as Outbreak Wanes

BLOOMBERG  By Simeon Bennett and Makiko Kitamura                                                       Jan. 21, 2015
(Two links. Scroll below.)

Ebola remains a global health emergency, the United Nations said today as it sought another $1 billion in donations to fight the deadly outbreak in West Africa.

More money is needed for the World Health Organization, Unicef and the World Food Programme, David Nabarro, the UN’s special envoy for Ebola, said at a briefing today at the World Economic Forum annual meeting in Davos, Switzerland.

“We can’t let down our guard,” Tom Frieden, director of the U.S. Centers for Disease Control and Prevention, said in a Bloomberg Television interview at Davos. “We have to get over the finish line and then learn from this experience to build better systems so that it doesn’t get out of control the next time” an infectious disease epidemic occurs.

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UN Ebola Chief Calls for Final Funding Push to Defeat Virus in West Africa

      

Ebola treatment centres have often not been completed until the virus has passed its peak.
Photograph: Francisco Leong/AFP/Getty Images

UN’s lead Ebola co-ordinator en route to Davos says last third of the $1.5bn pledged to tackle disease needs to be paid in order to end the outbreak

theguardian.com - by Sarah Boseley - January 20, 2015

Half a billion dollars of aid pledged to end the Ebola outbreak in west Africa still hasn’t been paid, according to the UN’s response co-ordinator.

Dr David Nabarro, in London and on his way to Davos to discuss progress against Ebola and future plans, said about two-thirds of the promised $1.5bn had been paid so far. “This last third is the most precious money but probably the most difficult money,” he told the Guardian. “My focus over the next few days here and in Davos is trying to ensure we have enough money to enable the task to be completed.

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Splinter Ebola Outbreaks Hinder Fight Against Virus: UN

BLOOMBERG      by  Jason Gale                                                                 Jan. 19, 2015

West Africa’s Ebola epidemic has morphed into several micro-outbreaks of varying intensity and with the potential to reignite more widespread contagion, a United Nations official said.

The pattern of spread has become more nuanced and complex, occurring over a wider area, David Nabarro, the UN Secretary-General’s special envoy on Ebola, said in a report by the Global Ebola Response Information Centre.

The 36-page publication, dated January 2015, outlines progress to date and changes in the global response needed to end the deadly scourge, which began in December 2013 in a remote area of Guinea, near the border with Liberia and Sierra Leone. ...

“Ending the outbreak will not be easy because the disease is being transmitted in three countries with a collective land area greater than the United Kingdom,” Nabarro said. “Success can only be achieved if communities themselves understand the nature of the outbreak and act in ways that reduce their likelihood of becoming infected.”

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Mali government, UN declare country Ebola-free

AFP                                                                Jan. 18, 2015

BAMAKO - The Malian government and the United Nations on Sunday declared the country free of Ebola after 42 days without any new cases of the deadly virus.

A man washes his hand in the village of Kouremale, Mali, to help prevent the spread of Ebola.

Health Minister Ousmane Kone said no confirmed cases had been registered since December 6 when the last Ebola patient had tested negative.

The west African country "had come out" of the epidemic, Ibrahima Soce Fall, the head of the Malian office of the United Nations Mission for Ebola Emergency Response (UNMEER), confirmed.

Health Minister Ousmane Kone said no confirmed cases had been registered since December 6 when the last Ebola patient had tested negative.

Read complete story.

http://news.yahoo.com/mali-government-un-declare-country-ebola-free-221318115.html

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Interview with Dr. David Nabarro, United Nations Special Envoy for Ebola

UNITED NATIONS NEWS CENTRE                                                               Jan.16, 2015

David Nabarro,Special Envoy on Ebola since August 2014, ...spoke with the UN News Centre in New York between his latest visit to Liberia, Guinea and Sierra Leone and a trip around Europe where he will visit the World Economic Forum and national capitals, seeking more resources to continue the fight against the outbreak. He described the reducing intensity of the outbreak, the shift in focus of responders and his growing confidence that the outbreak can be beaten. He also stressed the need for continued vigilance and more international support – in the form of people, materials and money – and looked forward to approval of a potential vaccine for the disease.

Excerpt:  " I’d like to start by describing the outbreak as it appears right now, and then I’d like to talk about the way in which the national Government and local communities are responding and the ways in which the international community is helping them.

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Ebola Death Toll Rises in West Africa While Americans' Interest Wanes

       

cbsnews.com - by Jessica Firger - January 8, 2015

Although it's largely dropped out of the headlines in this country, the Ebola outbreak continues to ravage West Africa. . . . Six out of 10 patients currently hospitalized with the virus will die, and a huge number of victims still aren't receiving medical care, which has allowed this public health crisis to continue to escalate at an alarming pace.

Yet many Americans may be under the impression that the Ebola crisis is winding down.

(READ COMPLETE ARTICLE)

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CDC - Mapping for Ebola: A Collaborative Effort

                

cdc.gov - January 14, 2015

One of the difficulties faced by teams responding to the current Ebola outbreak in West Africa is identifying individuals and communities residing in remote areas. Existing maps of these regions either do not exist or are inadequate or outdated. This means that basic data like location of houses, buildings, villages, and roads are not easily accessible, and case finding and contact tracing can be extremely difficult.

To help aid the outbreak response effort, volunteers from around the world are using an open-source online mapping platform called OpenStreetMap (OSM) to create detailed maps and map data of Guinea, Sierra Leone, Liberia, and parts of Mali.

(READ COMPLETE ARTICLE)

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