Half of Americans interested in getting updated COVID shot, Reuters/Ipsos poll shows About half of Americans are interested in getting an updated COVID-19 vaccine more than three years after the virus infected millions and upended daily life across the United States and around the world. Ahmed Aboulenein,Jason Lange Reuters

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COVID cases update: 5 worst hit states see positive tests fall, others rise New COVID-19 hospitalizations have been rising through the end of summer, after falling steadily week after week since January. Newsweek

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CDC calls Florida's advice against new COVID booster 'dangerous' Florida has the highest proportion of counties recording "moderate" COVID hospitalization levels in the U.S. Experts explain why the state is seeing so many cases. ABC News ABC News

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Earth is outside its 'safe operating space for humanity' on most key measurements, study says A new study of Earth's health says the planet is outside its “safe operating space for humanity” on six out of nine key measurements. AP News

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97% of Americans saw hotter temps caused by climate change Climate change doubled and tripled the chances of high temperatures, analysis shows. Alex Fitzpatrick Axios

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Where climate change most affected summer temperatures, 2023

(See interactive map.)

Study: Black cancer patients have much higher rates of COVID hospital stays MalaikaCasal / iStock CIDRAP

Race, COVID-19 infections, and chronic disease contributed to higher COVID-related hospitalization rates for Black patients compared to white patients, according to new research from scientists at Louisiana State University (LSU) Health, New Orleans, School of Public Health published in the Journal of the National Cancer Institute.

Moderna flu shot succeeds in late-stage study Moderna on Wednesday said its flu vaccine had generated a stronger immune response against all four A and B strains of the influenza virus compared to traditional flu shots in a late-stage trial, sending shares up about 6% in early trading. Patrick Wingrove Reuters

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US pharmacy chains gear up to administer updated COVID shots U.S. drugstore chains CVS Health and Walgreens Boots Alliance said on Wednesday that updated COVID-19 vaccines would be available at their stores as soon as this week. Reuters Reuters

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Shots were being delivered in some locations on Wednesday, including at a Northwell Health facility in New York.

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Opinion | This Isn't COVID's Final Act We must keep the virus, and long COVID, center stage Stuart Katz, MD, Alice Perlowski, MD, MA, and Brittany Taylor, MPH medpagetoday

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What are the side effects of the new COVID vaccine? CDC votes to approve booster The CDC recommends the updated COVID-19 vaccine for everyone ages six months and older. Here's when you should get the shot, what side effects to expect, and more. TODAY

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The new vaccine is targeting subtypes of the omicron variant that not all of us have been exposed to yet ... so it’s not quite a booster. This is trying to give us immunity against a different version of the virus,” Dr. Priya Sampathkumar, infectious disease specialist at the Mayo Clinic, tells TODAY.com. ...