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At Davos, U.N. Appeals For Final $1 Billion To Fight Ebola

             

Fabrice Coffrini via Getty Images

huffingtonpost.com - by Ben Hirschler

DAVOS, Switzerland, Jan 21 (Reuters) - United Nations agencies need a final $1 billion to fight West Africa's deadly Ebola epidemic as experts move to a new phase involving a massive detective operation to trace remaining cases, the U.N. Ebola chief said on Wednesday.

David Nabarro estimated that an overall total of $4 billion in new money, equivalent to all the aid committed so far, was needed by relief agencies and the worst affected countries themselves to end the epidemic and "help these countries to get back to the economic trajectory they had." 

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WHO Declares Ebola Outbreak In West Africa Over After Liberia Found Free Of The Disease

submitted by George Hurlburt

         

Zoom Dosso / AFP / Getty Images

It’s been more than 42 days since the last case – although officials warn that it is likely to return.

CLICK HERE - WHO - Latest Ebola outbreak over in Liberia; West Africa is at zero, but new flare-ups are likely to occur

buzzfeed.com - by Tom Chivers - January 14, 2016

The World Health Organization (WHO) has declared that Liberia is free of Ebola.

The west African country hasn’t seen a new case in 42 days. That’s the measure the WHO uses to determine whether an outbreak is still ongoing.

It means that, for the first time since December 2013, the whole of West Africa (and the world) is free of the disease.

It’s been the worst Ebola outbreak in history, killing at least 11,000 people, mainly in Guinea, Liberia, and Sierra Leone.

However, the WHO warns that new cases are likely.

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How Post-Ebola Syndrome is Making Life Difficult After the Dreaded Disease

submitted by Gavin Macgregor-Skinner

Al Jazeera America - (Tonight) Thursday, Jan 14, 2016 at 930pm EST 

Survivors of Ebola report strange symptoms as America Tonight examines how post-Ebola syndrome is making life difficult after the dreaded disease. (new, 30 minutes)

CLICK ON THE LINK BELOW - Watch at 930pm EST on Thursday, Jan 14, 2016
http://america.aljazeera.com/watch/shows/america-tonight.html

 

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Quantifying Poverty as a Driver of Ebola Transmission

                                                  

journals.plos.org - Fallah MP, Skrip LA, Gertler S, Yamin D, Galvani AP (2015) Quantifying Poverty as a Driver of Ebola Transmission.
December 31, 2015 - PLoS Negl Trop Dis 9(12): e0004260. doi:10.1371/journal.pntd.0004260

Abstract

Background

Poverty has been implicated as a challenge in the control of the current Ebola outbreak in West Africa. Although disparities between affected countries have been appreciated, disparities within West African countries have not been investigated as drivers of Ebola transmission. To quantify the role that poverty plays in the transmission of Ebola, we analyzed heterogeneity of Ebola incidence and transmission factors among over 300 communities, categorized by socioeconomic status (SES), within Montserrado County, Liberia.

CLICK HERE - Quantifying Poverty as a Driver of Ebola Transmission

 

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A New Weapon in Fight Against Ebola

The team has achieved an unprecedented goal: connecting 12 fullerenes, each one endowed with 10 sugar moieties, to other central fullerene, thus mimicking the presentation of carbohydrates surrounding the Ebola virus.  Credit: N. Martín & B. Illescas / UCM

CLICK HERE - A giant fullerene system inhibits the infection by an artificial Ebola virus

CLICK HERE - STUDY - Synthesis of giant globular multivalent glycofullerenes as potent inhibitors in a model of Ebola virus infection

scitechconnect.elsevier.com - by SPLICE - November 19, 2015

A discovery which may lead to the elimination of Ebola infections was published in Nature Chemistry a few days ago. The investigators reported that giant fullerene system inhibits the cell infection by an artificial Ebola virus.

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Is Ebola Virus One-Up Against Bats?

submitted by George Hurlburt      

         

CLICK HERE - STUDY - Filovirus receptor NPC1 contributes to species-specific patterns of ebolavirus susceptibility in bats

socialnews.xyz - December 24, 2015

Ebola virus and bats have been waging a molecular battle for survival that may have started at least 25 million years ago, revealed a new study led by an Indian-origin scientist.

The findings shed light on the biological factors that determine which bat species may harbour the virus between outbreaks in humans and how bats may transmit the virus to people. . . .

. . . The study was published online in the journal eLife.

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We’ve Learnt Many Lessons from This Outbreak and From the Response – Dr. David Nabarro, Special Envoy on Ebola

          

Dr. David Nabarro, Special Envoy on Ebola, at a press conference in New York in November 2015. UN Photo/Loey Felipe

un.org

10 December 2015 – In August 2014, amid a rapidly growing outbreak of Ebola, Dr. David Nabarro was tasked with providing strategic guidance for an enhanced international response, and galvanizing essential support for affected communities and countries. As the Secretary-General’s Special Envoy on Ebola, Dr. Nabarro played a key role in responding to the outbreak, which mainly affected Guinea, Liberia and Sierra Leone, and claimed more than 11,300 lives to date.

While the Ebola outbreak in West Africa has declined significantly in recent months, it is not completely over, making it all the more vital for everyone involved in the response to remain vigilant and focused on stopping the outbreak, staying at zero cases and preventing re-emergence. The Office of the Special Envoy will end its mandate on 31 December 2015, but the UN system will continue to remain fully engaged with the affected countries. 

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Liberia’s Ebola Outbreak Largely Traced to One Source

            

BRANCHING OUT  In Liberia, a single lineage of Ebola virus (middle dot) split into subgroups as it passed from person to person and mutated. Each dot is a slightly different version of the virus within the subgroups. Dot size indicates how many people carried that version. Researchers tracked the virus as it spread from Liberia (blue) into Guinea (red) and Mali (yellow).  J.T. Ladner et al/Cell Host & Microbe 2015

CLICK HERE - STUDY - Evolution and Spread of Ebola Virus in Liberia, 2014–2015

Genetic analysis of third hard-hit country fills in gaps in virus’ spread and evolution

sciencenews.org - by Tina Hesman Saey - December 9, 2015

A single introduction of the Ebola virus led to most cases of the deadly disease in Liberia, a new genetic study suggests.

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Mathematical Modeling of the West Africa Ebola Epidemic

eLife 2015;10.7554/eLife.09186 - December 8, 2015
DOI: http://dx.doi.org/10.7554/eLife.09186

Abstract

As of November 2015, the Ebola virus disease (EVD) epidemic that began in West Africa in late 2013 is waning. The human toll includes more than 28,000 Ebola virus disease (EVD) cases and 11,000 deaths in Guinea, Liberia, and Sierra Leone, the most heavily-affected countries. We reviewed 66 mathematical modeling studies of the EVD epidemic published in the peer-reviewed literature to assess the key uncertainties models addressed, data used for modeling, public sharing of data and results, and model performance. Based on the review, we suggest steps to improve the use of modeling in future public health emergencies.

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