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Italian nurse cured of Ebola

AFP                                                                                                June 10, 2015

Rome -- An Italian nurse who contracted Ebola while working in Sierra Leone with medical charity Emergency has been cured and left hospital on Wednesday, the health ministry announced.

Stefano Marongiu, a male nurse from Sardinia, has spent the last month receiving treatment at the Spallanzani infectious diseases clinic in Rome.

He was the second Italian to contract the disease after Fabrizio Pulvirenti, a Sicilian doctor who had also worked for Emergency in Sierra Leone.

The doctor, who left hospital in January, was treated at the same clinic with a combination of experimental drugs and the blood plasma of an Ebola survivor.

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How Computer Modelers Took On the Ebola Outbreak

submitted by Sarah Slaughter         

           

At The Epidemic’s Epicenter: A Liberian child sits in an Ebola isolation ward housing people who might have contracted the contagious disease.  Photo: John Moore/Getty Images

Did real-time epidemic modeling save lives in West Africa?

spectrum.ieee.org - by David Brown - May 28, 2015

. . . “agent-based” models will give a more nuanced picture of how pathogens affect and sicken a population. “This is the wave of the future,” says Stephen Eubank, deputy director of the Virginia Tech lab. “It’s going to take a concerted effort to gather the data and the expertise. But it’s going to happen.”

And so, too, will another Ebola outbreak.

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Ebola crisis: UN's Ebola mission HQ in Ghana to close

BBC by Anne Soy                                                              June 9, 2015
The UN's emergency Ebola response headquarters in Ghana's capital, Accra, is to close as the outbreak slows.

The head of the mission, Peter Graaff, met the Ghanaian president to thank the country for hosting the agency since it was set up in September last year.

A small team will stay until the end of June to co-ordinate air operations, the agency, known as Unmeer, said.

Ghana has not been affected by the epidemic in West Africa, which has killed more than 11,000 people.

The BBC's Africa health correspondent Anne Soy says the mission set up its headquarters in Accra as it was far enough away from the affected countries, where there was logistical lockdown, but close enough the epicentre of the outbreak.
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http://www.bbc.com/news/world-africa-33063900

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NIH Study Finds No Evidence of Accelerated Ebola Virus Evolution in West Africa

NIH Institute of Allergy and Infectious Diseases (NIAID)                            June 9, 2015

According to a recent report from the National Institutes of Health (NIH), the current strain of the Ebola virus that is circulating through West Africa is called the Makona strain and is less aggressive than the original Mayinga strain that, which was isolated in Central Africa in 1976.
When compared to the Mayinga strain, the Makona strain takes approximately two additional days to start terminal disease in an animal subject. This is an important discovery to scientists, as they wonder whether the Ebola strain in West Africa will grow more severe over time.

The test subjects were cynomolgus macaques. Researchers used these animals to model disease and infection in humans. The scientists infected three macaques with the Mayinga strain from 1976 and an additional three with the Makona strain from 2015.

 
 Ebola virus, isolated in November 2014 from patient blood samples obtained in Mali. The virus was isolated on Vero cells in a BSL-4 suite at Rocky Mountain Laboratories.
Credit: NIAID RML

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Akon Launches Solar Academy That Will Supply Electricity to 600,000,000 People in Africa

Photo: Denis Van Tine/AP Photo

The musician is giving back to people in a major way.

theroot.com - by Yesha Callahan - June 2, 2015

When he’s not singing or producing music, Akon is busy providing sustainable living options to people in African countries. The Senegalese-American singer’s initiative, appropriately called Akon Lighting Africa, aims to supply electricity to 600 million people in Africa who lack it with the launch of the Solar Academy.

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CLICK HERE - Akon Lighting Africa

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G7 states vow to wipe out Ebola but offer little concrete action

REUTERS                                                      June 8, 2015

KRUEN, Germany - Leaders of the Group of Seven industrial nations pledged on Monday to wipe out Ebola but offered little in terms of concrete action, disappointing non-governmental organisations.

G7 leaders said in a communique at the end of a two-day summit in the Bavarian Alps that they would offer help to at least 60 nations, including in West Africa, over the next five years to help prevent outbreaks from turning into epidemics.

More than 11,000 people have died in the Ebola outbreak in West Africa since the first reported case in March 2014. The G7 said the crisis showed it was necessary to enhance the world's ability to prevent, detect and respond to such emergencies.

The G7 nations said they would work together to combat future epidemics and boost or establish strategies to quickly deploy teams of experts with a variety of skills via a common platform, but their communique was thin on detail.

Florian Westphal, General Director of Medecins Sans Frontieres (MSF) Germany, said the leaders had done little to ensure epidemics would not spiral out of control in future....

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Transmission Models of Historical Ebola Outbreaks

CDC,  by John Drake and others Volume 21, Number 8—August 2015

 To guide the collection of data under emergent epidemic conditions, we reviewed compartmental models of historical Ebola outbreaks to determine their implications and limitations. We identified future modeling directions and propose that the minimal epidemiologic dataset for Ebola model construction comprises duration of incubation period and symptomatic period, distribution of secondary cases by infection setting, and compliance with intervention recommendations....

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How Mobile Technology Is Bringing Trauma Relief After Ebola

SINGULARITY HUB   by Nathan and Elie Calhoun                                                   June , 2015

....the promise of mobile technology is that we can connect the farthest, most remote corners of the globe to the Internet—where a treasure trove of information and applications can be had nearly for free.

 For aid workers, this technology is proving a powerful, even revolutionary tool.

We hope our new community mental health app will demonstrate a new depth of potential impact.

When we started designing our psychosocial services app for Liberian communities recently ravaged by Ebola, we thought we’d first need to justify the very idea of focusing on mental health in a country facing so many pressing concerns.

The health system in Liberia confronts massive challenges. When hospitals are non-existent or seriously under-staffed, when malaria is endemic and young mothers die during childbirth—it can be tempting to ask people suffering from trauma to simply “toughen up.”

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Managing the Risk and Impact of Future Epidemics: Options for Public-Private Cooperation

submitted by Denis Gilhooly

World Economic Forum
Prepared in collaboration with the Boston Consulting Group (BCG)

CLICK HERE - Managing the Risk and Impact of Future Epidemics: Options for Public-Private Cooperation

CLICK HERE - REPORT - Managing the Risk and Impact of Future Epidemics: Options for Public-Private Cooperation
(20 page .PDF report)

The Ebola outbreak in West Africa was a public health emergency of new proportions that presented unprecedented challenges for the international community. Aside from the significant social and economic impact it had on many West African countries, the epidemic also triggered a range of innovative, flexible partnership responses from businesses and civil society that complemented the channels of official assistance to affected countries.

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The contribution of Ebola viral load at admission and other patient characteristics to mortality in a Médecins Sans Frontières (MSF) Ebola Case Management Centre (CMC), Kailahun, Sierra Leone, June –October, 2014

m.jid.oxfordjournals.org - J Infect Dis. (2015) doi: 10.1093/infdis/jiv304 First published online: May 22, 2015

Abstract

This paper describes patient characteristics, including Ebola viral load, associated with mortality in an MSF Ebola case management centre.

Out of 780 admissions between June and October 2014, 525 (67%) were positive for Ebola with a known outcome. The crude mortality rate was 51% (270/525). Ebola viral load (whole blood sample) data was available on 76% (397/525) of patients. Univariate analysis indicated viral load at admission, age, symptom duration prior to admission and distance travelled to the CMC were associated with mortality (p value<0.05). The multivariable model predicted mortality in those with a viral load at admission greater than 10 million copies per millilitre (p value<0.05, Odds Ratio>10), aged 50 years or more (p value=0.08, Odds Ratio=2) and symptom duration prior to admission less than 5 days (p value=0.14). The presence of confusion, diarrhoea and conjunctivitis were significantly higher (p value<0.05) in Ebola patients who died.

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