Guinea Resilience System

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Thu, 2013-07-04 12:32 — mdmcdonald

The Guinea Resilience System working group is focused on the development of Resilience Systems in Guinea.

The mission of the Guinea Resilience System working group is to develop Resilience Systems and their nested subsystems in Guinea.

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Members

Abdoulaye Drame	Aboubacar Conte	Anthony	Boubacar Kaba	Carrielaj	Chisina Kapungu
Elhadj Drame	Hadiatou Balde	Ismael Dioubate	John Wysham	Kathy Gilbeaux	Lancine Konate
Mamadou Diallo	Mamadou Moustap...	Mamadou Sylla	mdmcdonald	MDMcDonald_me_com	mike kraft
Norea	Souleymane Drame

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guinea-resilience-system@m.resiliencesystem.org

Stopping the next pandemic today

Sun, 2015-06-07 09:27 — mike kraft

OP-ED WASHINGTON POST, June 7, 2015

By Ron Klain, the White House Ebola response coordinator from October 2014 to February.

....To the extent there is discussion of improving the international response to epidemics, the focus has been on the need to reform the World Health Organization. Such reforms are badly needed, but even a fully effective WHO will not close the most gaping holes in the world’s epidemic response system. Even if the WHO did a better job of recognizing outbreaks that pose a risk of epidemic and alerting the world that action is needed, it does not have the substantial response function needed to combat such an epidemic. Recent discussions about creating a WHO response function — assuming that the agency could be trusted to manage it — rely largely on overburdened and underfunded nongovernmental organizations to staff a response. Thus, any new WHO response capacity will lack military-style mobile hospitals ready to be deployed; battalions of medical personnel with accompanying security support to isolate and treat the infectious and the ill; or a medical airlift capacity to move patients to places where they can get help...

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Ebola Virus Disease Outbreak in Nigeria: Transmission Dynamics and Rapid Control

Sat, 2015-06-06 23:41 — Kathy Gilbeaux

ncbi.nlm.nih.gov - Epidemics. 2015 Jun;11:80-4. doi: 10.1016/j.epidem.2015.03.001. Epub 2015 Mar 21

Abstract

International air travel has already spread Ebola virus disease (EVD) to major cities as part of the unprecedented epidemic that started in Guinea in December 2013. An infected airline passenger arrived in Nigeria on July 20, 2014 and caused an outbreak in Lagos and then Port Harcourt. After a total of 20 reported cases, including 8 deaths, Nigeria was declared EVD free on October 20, 2014. We quantified the impact of early control measures in preventing further spread of EVD in Nigeria and calculated the risk that a single undetected case will cause a new outbreak. We fitted an EVD transmission model to data from the outbreak in Nigeria and estimated the reproduction number of the index case at 9.0 (95% confidence interval [CI]: 5.2-15.6). We also found that the net reproduction number fell below unity 15 days (95% CI: 11-21 days) after the arrival of the index case. Hence, our study illustrates the time window for successful containment of EVD outbreaks caused by infected air travelers.

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Managing the Risk and Impact of Future Epidemics: Options for Public-Private Cooperation

Sat, 2015-06-06 23:01 — Kathy Gilbeaux

submitted by Denis Gilhooly

World Economic Forum
Prepared in collaboration with the Boston Consulting Group (BCG)

CLICK HERE - Managing the Risk and Impact of Future Epidemics: Options for Public-Private Cooperation

CLICK HERE - REPORT - Managing the Risk and Impact of Future Epidemics: Options for Public-Private Cooperation
(20 page .PDF report)

The Ebola outbreak in West Africa was a public health emergency of new proportions that presented unprecedented challenges for the international community. Aside from the significant social and economic impact it had on many West African countries, the epidemic also triggered a range of innovative, flexible partnership responses from businesses and civil society that complemented the channels of official assistance to affected countries.

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The contribution of Ebola viral load at admission and other patient characteristics to mortality in a Médecins Sans Frontières (MSF) Ebola Case Management Centre (CMC), Kailahun, Sierra Leone, June –October, 2014

Sat, 2015-06-06 21:48 — Kathy Gilbeaux

m.jid.oxfordjournals.org - J Infect Dis. (2015) doi: 10.1093/infdis/jiv304 First published online: May 22, 2015

Abstract

This paper describes patient characteristics, including Ebola viral load, associated with mortality in an MSF Ebola case management centre.

Out of 780 admissions between June and October 2014, 525 (67%) were positive for Ebola with a known outcome. The crude mortality rate was 51% (270/525). Ebola viral load (whole blood sample) data was available on 76% (397/525) of patients. Univariate analysis indicated viral load at admission, age, symptom duration prior to admission and distance travelled to the CMC were associated with mortality (p value<0.05). The multivariable model predicted mortality in those with a viral load at admission greater than 10 million copies per millilitre (p value<0.05, Odds Ratio>10), aged 50 years or more (p value=0.08, Odds Ratio=2) and symptom duration prior to admission less than 5 days (p value=0.14). The presence of confusion, diarrhoea and conjunctivitis were significantly higher (p value<0.05) in Ebola patients who died.

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West Africa Struggles to Rebuild Its Ravaged Health-Care System

Fri, 2015-06-05 21:08 — mike kraft

WALL STREET JOURNAL by Betsy McKay June 4, 2015
HARPER, Liberia --The deadly disease may have receded, but it is still exacting a heavy toll. Run-down, poorly staffed and equipped health facilities allowed Ebola to explode.

Since it was identified in early 2014, the epidemic has claimed the lives of 507 health-care workers in three West African countries, all of which already were short of medical professionals. The health-care system was so overwhelmed with Ebola victims that many other patients couldn’t receive care for malaria, heart disease or pregnancy complications. That bill is coming due.

“There are more people who are going to die from Ebola, but not have Ebola,” says Paul Farmer, a Harvard professor and co-founder of the Boston-based charity Partners in Health.

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Ebola Response Reveals the Need for New Models for Collaboration Between the Private and Public Sectors

Fri, 2015-06-05 11:41 — mike kraft

A Report by the World Economic Forum and BCG Analyzes the Private Sector's Response to the Ebola Outbreak and Distills Lessons for Public-Private Partnerships in Future Health Crises

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BOSTON CONSULTING GROUP -MARKETWIRED June 4, 2014

CAPE TOWN, SOUTH AFRICA-- The private sector played an important role in the global response to the Ebola outbreak in West Africa not only by providing financial and in-kind donations but also by acting as a partner to support response activities.

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Global health leaders ask G7 for post-Ebola rapid response unit

Fri, 2015-06-05 10:48 — mike kraft

(Two stories. Scroll down.)
REUTERS by Kate Kelland June 5, 2015
LONDON -- Global health leaders will ask G7 leaders this weekend to back the creation of a specialist rapid response unit to tackle outbreaks of infectious killer diseases.

The corpse of a patient who passed away is given back to the family for funerals after being decontaminated by the MSF teams. It was washed with chlorine solution and put it in a hermetic bag also disinfected to leave the high risk area.

The move reflects how the World Health Organization in particular was caught unprepared last year by Ebola, which spread through three West African countries, has killed 11,000 people, and will not be stamped out before the end of this year.

Jeremy Farrar, director of the Wellcome Trust global health charity, said the unit should come under the WHO, but be free of bureaucracy and able to act independently "in days" when a potentially fatal epidemic begins...

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Ebola activity heats up as West Africa's rainy season begins

Thu, 2015-06-04 14:50 — mike kraft

CIDRAP NEWS by Lisa Schnirring June 3, 2015

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Zoloft Could Be a Treatment for Ebola Virus

Wed, 2015-06-03 21:02 — mike kraft

Researchers have identified two FDA-approved drugs that may be effective against the Ebola virus. This could shorten the time for developing new treatments.

HEALTHLINE NEWS by Shawn Radcliffe June 3, 2015

With a fast-moving epidemic like Ebola, doctors need to make use of every tool at their disposal. This includes giving a second life to already-approved drugs....

One research team is hoping to ease the epidemic by shortening the lengthy drug development process.

Their approach? Sifting through hundreds of existing drugs and other compounds for ones that might work against the Ebola virus....

Additional screening narrowed the list down to two potential drug candidates: Bepridil, a calcium channel blocker used to treat heart disease, and sertraline, an antidepressant more commonly known as Zoloft.

Both drugs are already approved by the FDA, although not for use against the Ebola virus.

Read complete story.

http://www.healthline.com/health-news/zoloft-could-be-a-treatment-for-ebola-virus-060315#1

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Ebola outbreak thrusts MSF into new roles

Wed, 2015-06-03 20:41 — mike kraft

Relief agency sees its mission expanding after leading response to West Africa epidemic.

NATURE by Erika Check Hayden June 3, 2015

GENEVA -- Joanne Liu, president of Médecins Sans Frontières (MSF), is not overly concerned with diplomacy. Participating in a panel in Geneva, Switzerland, on 20 May with officials from the United Nations, the World Health Organization (WHO), Liberia and Sierra Leone, she propped her head on her hand, stared into space and rolled her eyes during another speaker’s remarks. When she spoke, she excoriated the world for leaving West Africa vulnerable to the largest Ebola epidemic in history. “We’re failing, guys,” she said.

Joanne Liu visiting an MSF trauma centre in Kunduz, Afghanistan.