Ebola vaccine trial to combine GSK, Emergent Bio shots

REUTERS                                                                                                          March 16, 2015

LONDON  - Scientists are to test a new two-shot Ebola vaccine using an experimental shot from Britain's GlaxoSmithKline, which is already in clinical trials in Africa, and a new kind of booster from Emergent BioSolutions.

A health worker, left, injects a man in his arm with an Ebola vaccine in Conakry, Guinea, March 7, 2015. The World Health Organization is starting large-scale testing of an experimental Ebola vaccine in Guinea  to see how effective it might be in preventing future outbreaks of the deadly virus.  (AP Photo/ Youssouf Bah)

The Maryland-based biotech company said on Monday its modified vaccinia Ankara (MVA) Ebola Zaire vaccine would be used in an initial Phase I clinical study to be conducted by researchers at the University of Oxford.

Although Ebola case numbers have fallen to a low level, drug companies are still pushing ahead with efforts to develop an effective vaccine, which may help fight the next outbreak, even if it does not come in time for the current epidemic.

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Sierra Leone VP Samuel Sam-Sumana 'goes into hiding'

BBC                                                       March 14, 2015

Sierra Leone's Vice-President Samuel Sam-Sumana has gone into hiding while he seeks political asylum at the US embassy in the capital, Freetown.

               Relations between President Ernest Bai Koroma (left) and Mr Sam-Sumana (right) have long been frosty

Mr Sam-Sumana told the BBC he and his wife fled their home after "a tip-off" that soldiers were surrounding it.

The move comes a week after his expulsion from the ruling party.

Two weeks ago, Mr Sam-Sumana said he was putting himself in quarantine for 21 days after one of his bodyguards died of the Ebola virus.

Police and army sources confirmed to the BBC's Umaru Fofana in Freetown that troops were sent to the vice-president's residence on Saturday morning.However, Information Minister Alpha Kanu told the BBC that the soldiers merely went to Mr Sam-Sumana's house to "strengthen the quarantine".

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http://www.bbc.com/news/world-africa-31885713

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A Life-Saving Comic: Educating Children in West Africa about Ebola

BIOSECTOR PRESS  by Chris Shilling                    March 9, 2015

As efforts intensify at all levels by international health organisations and on the ground by community health workers in providing treatment, supplies and preventive measures,  young people and children – perhaps the ones most affected – need to have access to good health education resources to help them better understand both the medical and health aspects of Ebola.

To address this issue, Afrelib is working in partnership with Medikidz, (http://www.medikidz.com/gb-en/) the world’s first medical information company aimed at children, to produce learning material in an interactive, comic book format. With this health education comic, it should be possible to provide easy-to-understand and engaging information so that it not only helps in disseminating good preventive measures as recommended by public health organisations but also helps them in dealing with the cultural and social issues surrounding this epidemic.

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This smart ‘band-aid’ could help the world beat Ebola

MASHABLE  by  Lance Ulanoff                                                                   March 14, 2015

AUSTIN — The international fight against Ebola is far from over. Just this week, new patients arrived in U.S. hospitals for treatment. But back in Africa where healthcare workers have battled hundreds of cases at a time, officials are struggling to find smart solutions that can help ensure the safety of caregivers, offer more comprehensive and speedy care and add 21st century solutions to their disease-fighting arsenal.

Wearable technology is very close to joining the fight....

Wendy Taylor, Direct of the USAID Center for Accelerating Innovation holds a MultiSense Memory patch prototype

On Saturday at SXSW, The U.S. Agency for International Development (USAID) unveiled both a new biomedical suit and the MultiSense Memory wearable sensor:

Even with a new biomedical suit in the wings, doctors in the field still face significant challenges. “Tools are hard to use in an Ebola setting — you can’t use a stethoscope,” said Taylor.

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'You cannot stop Ebola' US experts warned British troops

THE TELEGRAPH    by Ben Farmer                                                                           March 15, 2015

British commanders were warned last year it was impossible to halt Ebola in Sierra Leone and they were about to lose control of the deadly outbreak in its capital, it has been disclosed.

British Defence Secretary Michael Fallon on the RFA Argus hospital ship in Sierra Leone Photo: Will Wintercross/The Telegraph

United Nations and American experts said there was nothing British troops could do to stop the virus rampaging through the country and they were about to “lose Freetown”.

Loss of the capital would have triggered an international evacuation from the country, the commander of British troops revealed, as he explained for the first time the scale of the outbreak they have been fighting....

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Watch closely and explain frequently: Liberia's Ebola lessons

REUTERS   By James Harding Giahyue and Emma Farge                                                   March 13, 2015

MONROVIA/DAKAR - Seven months after Ebola paralysed Liberia's capital, Friday marked 21 days since the country registered a case of the virus - offering lessons to its neighbors on the importance of surveillance and education in beating the deadly epidemic....

 A massive influx of international aid, including crucial U.S. military assistance, helped Liberia to turn the tide of the outbreak.

But, notes Tariq Riebl, Oxfam's Ebola response manager in Liberia, "What got us to the endgame is that communities took things into their own hands...."

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http://news.yahoo.com/watch-closely-explain-frequently-liberias-ebola-lessons-184507811.html;_ylt=AwrBJR6EmAVV3D0AbnTQtDMD

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10 Americans to leave Sierra Leone amid Ebola scare

ASSOCIATED PRESS                                                     March 15, 2015

FREETOWN, Sierra Leone (AP) — Ten clinicians with a Boston-based nonprofit organization responding to the Ebola outbreak in Sierra Leone are to be transported to the United States after one of their colleagues was infected with the deadly disease.

Partners in Health said in a statement Saturday that the medical workers would be evacuated on non-commercial aircraft and isolated in Ebola treatment facilities.

On March 11, a Partners in Health clinician in Sierra Leone tested positive for Ebola, and the 10 fellow workers "came to the aid of their ailing colleague," the group's statement said. They have not shown signs of Ebola, and Partners in Health said the evacuations were ordered "out of an abundance of caution."

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http://www.usatoday.com/story/news/world/2015/03/15/10-us-charity-staff-to-leave-sierra-leone-amid-ebola-scare/24804779/

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Exclusive: take a first look at the next generation ebola-protection suit

QUARTZ  by Grace Dobush                                         March 13, 2015

AUSTIN, Texas—Perhaps the most surprising and important product debuting at SXSW Interactive this year is a personal protective equipment (PPE) prototype for health care workers dealing with Ebola, a tangible result of the U.S. government adapting the culture of innovation and design thinking so key in the startup world.

A team from the U.S. Agency for International Development demonstrated the traditional Ebola suit and the new suit in a preview for Quartz....

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Vaccines Face Same Mistrust That Fed Ebola

NEW YORK TIMES  by and         March 14, 2015

MONROVIA, Liberia — West Africa’s Ebola epidemic may be waning, but another outbreak in the future is a near certainty, health officials say.

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Lack of Ebola Cases Shifts Vaccine Trials Away From Liberia

TIME MAGAZINE  by Alexandra Sifferlin                                                                        March 13, 2015

The National Institutes of Health (NIH) may relocate its clinical trials of Ebola vaccines to Guinea, since there are no longer enough Ebola cases in Liberia for a proper efficacy trial.

On Feb. 2, the NIH launched an initial safety trial for two vaccines to protect against Ebola in Liberia. The plan was to test 600 people for overall safety and then launch a second phase of the trial in 27,000 people to see whether or not the vaccine prevents infection with Ebola virus compared to a placebo.

The safety test was successfully completed the week of March 9—but around the same time, Liberia announced that it had released its last confirmed patient from its Ebola treatment centers. ...

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The hidden cost of Ebola: thousands of measles deaths

VOX  by Julia Belluz                                            March 12, 2015

(Scroll down for full Science Journal study.)

As if being stricken by the most deadly virus known to man weren't enough, now, it seems, West Africa is on alert for outbreaks of vaccine-preventable diseases including measles, whooping cough, and tuberculosis.

A girl collects her family's laundry after drying it on a rooftop in the West Point township on January 31, 2015 in Monrovia, Liberia. Life has been disrupted by Ebola for many Liberians.

In a new study in the journal Science, researchers focused on measles — the most contagious virus recorded — and applied statistical models to quantify the likelihood of an epidemic in the three countries worst hit by Ebola, Liberia, Sierra Leone, and Guinea.

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Sierra Leone sees worrying spike in Ebola cases over week

ASSOCIATED PRESS  by Clarence Roy-Macaulay                                                      March 12, 2015
 FREETOWN --   Sierra Leone has seen a worrying spike in confirmed Ebola cases over the past week in four districts, the head of the national Ebola response center said Thursday.

New measures must now be put into place to contain the surges, said the head of the National Ebola Response Centre, Alfred Palo Conteh.

Fifteen cases were recorded Wednesday, along with 16 on Monday and Tuesday respectively, according to Sierra Leone's Ministry of Health and Sanitation.

"We are now on a bumpy road to zero number of cases to get to President Ernest Bai Koroma's target of March 31," said Palo Conteh. "It is frustrating."

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http://news.yahoo.com/sierra-leone-sees-worrying-spike-ebola-cases-over-141214859.html;_ylt=AwrBEiTD7gJVy2QANdbQtDMD

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2 Aid Workers In West Africa Are Infected With Ebola

NEW YORK TIMES  by Sheri Fink and Allan Cowell                                                         March 12, 2015

A worker from Partners In Health, the prominent American medical aid organization, and an emergency worker from the British military have been infected with the deadly virus in Sierra Leone, health officials said Thursday.

The Partners In Health worker was the first in that group to be infected since it made an ambitious commitment last fall to help combat Ebola in West Africa, and was the first American health worker in months to get the disease while working in the region. ...

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Ebola death toll passes 10,000: WHO

AFP                                                                                                                    March 12, 2015
(Scroll down for WHO report.)

Geneva -- The global death toll from the Ebola outbreak centred in west Africa has topped 10,000 out of more than 24,000 recorded cases, the World Health Organization said Thursday.

Almost all the deaths and cases have been reported in the three west African countries worst hit by the outbreak: Sierra Leone, Liberia and Guinea.

Sierra Leone, which has overtaken Liberia as the country with the most infections, counted 11,677 cases and 3,655 deaths as of March 10.

As of March 5, Liberia -- long the hardest-hit country -- had recorded a total of 9,343 and 4,162 deaths.

But the tide seems to be turning in the country which in August and September was reporting more than 300 new cases each week, with the WHO saying Wednesday that Liberia had registered no new cases since February 19.

In Guinea, where the outbreak started in December 2013, 3,330 Ebola cases and 2,187 deaths were recorded as of March 10.

The WHO said on Wednesday that the country had seen no new cases in the previous 10 days.

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UNMC dean who just returned from Sierra Leone, another Ebola expert agree: Fight not over

OMAHA WORLD-HERALD by  Bob Glissman                                                             March 11, 2015

  The West African countries hit hardest by the Ebola virus and the countries and groups that have helped battle the disease must remain vigilant if the number of new Ebola cases is to get to zero, health experts said Wednesday.
Dr. Ali Khan, dean of the University of Nebraska Medical Center’s College of Public Health, spent a month in Sierra Leone as a consultant on Ebola for the World Health Organization. 

Dr. Ali Khan, who returned to Omaha late last week after a month in Sierra Leone, said progress is evident, but he cautioned officials there against becoming complacent. “Because with a disease like Ebola,” he said, “all you need is one case to restart an outbreak or a cluster of cases.”

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