Ebola vaccine 'promising in African populations'

BBC     By Smitha Mundasad                                Dec. 22, 2014
The first-ever trial of an Ebola vaccine in Africa shows promising initial results, according to a report in the Lancet medical journal.

Scientists say it is a crucial step as other vaccines have shown lower levels of protection in African populations.

Tests involving Ugandan and American volunteers reveal the vaccine is so far safe and generates an immune response in both populations.

It provides reassurance for other trials currently underway, they say.

No proven vaccine exists to prevent people from getting the disease, though several trials are underway.

Researchers from the National Institutes of Health tested this experimental vaccine on healthy adults in Uganda, having first trialled it in the United States.

Dr Julie Ledgerwood, the lead researcher, said: "This is the first study to show comparable safety and immune response of an experimental Ebola vaccine in an African population.

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http://www.bbc.com/news/health-30577776

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U.S. to Complete Ebola Treatment Units in Liberia by End of December

WALL STREET JOURNAL by Junian E. Barnes and Felicia Schwartz                                                 Dec. 22, 2014
WASHINGTON—The U.S. will complete the last of its Ebola treatment units in Liberia by the end of December, setting the stage for the military to decide next month whether to send some service members home or send them to another West African country, the top U.S. commander in Liberia said Monday.

The U.S. will decide by mid-January whether to redeploy troops to Sierra Leone or Guinea or simply further shrink the size of the military mission in Liberia, Maj. Gen. Gary Volesky, the commander of the military’s Ebola task force, said in an interview with The Wall Street Journal.

The military task force has been involved in the building of 14 treatment units, in addition to the treatment unit completed before the 101st Airborne Division arrived. ...

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http://www.wsj.com/articles/u-s-to-complete-ebola-treatment-units-in-liberia-by-end-of-december-1419285448

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Untested Ebola drug given to patients in Sierra Leone causes UK walkout

THE GUARDIAN           by Sarah Boseley                                                                    Dec. 22, 2014

FREETOWN, Sierra Leone -- Ebola patients at a treatment centre in Sierra Leone have been given a heart drug that is untested against the virus in animals and humans, a move that has been deemed reckless by one senior scientist and has prompted UK medical staff at the centre to leave.

                British health workers help an Ebola patient in Freetown, Sierra Leone. Photograph: Baz Ratner/Reuters

A 14-strong team of British doctors, nurses and paramedics stopped working at the Lakka treatment centre in Freetown because of their concerns over what they considered the experimental and potentially dangerous use of the drug, and other safety issues.

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Chris Coons Travels To Liberia For Ebola Follow-Up

HUFFINGTON POST     by  Arthur Delany                                                                      Dec, 22, 2014

WASHINGTON -- Sen. Chris Coons (D-Del.) traveled to the West African nation of Liberia this week, partly to remind the American people that an Ebola epidemic is still going on, Coons told reporters Monday.

 

                     Sen. Chris Coons (D-Del.) elbow-bumps an Ebola survivor in Liberia. | Chris Coons Flickr | Flickr

"My hope was to remind the American people that this is an investment that helps keep the world safe, not just help Liberians, although helping Liberia is a worthy goal in and of itself," Coons said on a conference call in response to a question from HuffPost.

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Tekmira Inks Deal to Test New Ebola Drug in Humans

GENOMEWEB                                                                                                                        Dec. 22, 2014
NEW YORK -- Tekmira Pharmaceuticals announced today that it has signed a deal that will support the clinical testing of its experimental Ebola therapy designed against the strain of the virus behind the outbreak in West Africa.

Tekmira has long been developing an siRNA-based Ebola drug called TKM-Ebola, but a Phase I study of that agent was suspended by US regulators until the company could provide additional safety data. Earlier this year, Tekmira management indicated that that trial might not restart as early as anticipated since the firm had begun focusing on a version specifically for the Guinea strain of the Ebola virus, which is driving the ongoing outbreak.

Tekmira said it has now inked a manufacturing and clinical trial agreement with the University of Oxford to provide the new drug, called TKM-Ebola-Guinea, for clinical trials in West Africa. The university is the representative of the International Severe Acute Respiratory and Emerging Infection Consortium, which will be testing TKM-Ebola-Guinea in infected individuals with funding from the Wellcome Trust.

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Can the blood of Ebola survivors create a cure?

REUTERS       by  Julie Steenhuysen                                                                                 Dec. 22, 2014
CHICAGO --For months, Vanderbilt University researcher Dr. James Crowe has been desperately seeking access to the blood of U.S. Ebola survivors, hoping to extract the proteins that helped them overcome the deadly virus for use in new, potent drugs.

Blood samples from patients suspected of having the Ebola virus disease are prepared for transportation to Freetown for testing, at the Port Loko District Hospital September 27, 2014. Credit: Reuters/Christopher Black/WHO/Handout via Reuters

His efforts finally paid off in mid-November with a donation from Dr. Rick Sacra, a University of Massachusetts physician who contracted Ebola while working in Liberia. The donation puts Crowe at the forefront of a new model for fighting the virus...

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DoD extends review of Ebola quarantine policy

MILITARY TIMES By Andrew Tilghman                                                                                Dec. 19, 2014
Thousands of troops deployed to West Africa to help contain the Ebola virus will have to wait a few more weeks to find out whether the policy of 21-day quarantines after their redeployment will continue, military officials said.

The Pentagon has granted an extension on the deadline for reviewing the controversial rule requiring a 21-day, post-deployment quarantine. The review will now be completed by Jan. 30, 2015.

When Defense Secretary Chuck Hagel announced the quarantine on Oct. 29, he ordered military officials to conduct a review within 45 days to determine whether it was effective and necessary.

That review was due on Dec. 12, but Hagel granted a seven-week extension following a request from the chairman of the Joint Chiefs, Army Gen. Martin Dempsey.

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http://www.militarytimes.com/story/military/pentagon/2014/12/19/ebola-quarantine-review/20637663/?utm_source=December+22+2014+EN&utm_campaign=12%2F22%2F2014&utm_medium=email

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IMF policies blamed for Ebola spread in West Africa

BBC                                                                                                                       Dec. 22 2014

Spending cuts imposed by the International Monetary Fund (IMF) may have contributed to the rapid spread of Ebola in three West African states, UK-based researchers say.

                      Sierra Leone, along with Liberia and Guinea, have poor health facilities

It had led to "under-funded, insufficiently staffed, and poorly prepared health systems" in Sierra Leone, Liberia and Guinea, they said.

The IMF denied the allegation.

"A major reason why the Ebola outbreak spread so rapidly was the weakness of healthcare systems in the region, and it would be unfortunate if underlying causes were overlooked," said Cambridge University sociologist and lead study author Alexander Kentikelenis....

The IMF said in a statement that health spending in Guinea, Liberia and Sierra Leone had, in fact, increased in the 2010-2013 period.

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The Last Time the Arctic Was Ice-Free in the Summer, Modern Humans Didn’t Exist

A picture of people on ice and snow. Caption reads: Enjoy it while you can. Image: Thomas A. Brown and Simon T. BeltImage: A picture of people on ice and snow. Caption reads: Enjoy it while you can. Image: Thomas A. Brown and Simon T. Belt

slate.com - December 12th, 2014 - Eric Holthaus

Ice has been a relatively constant feature of the Arctic for most of the past 36 million years, but there have been some gaps. Scientists aren’t exactly sure what happened during the most recent major ice-free period, but it’s often considered an analog to our future, warmer Earth. The only difference is, the gap in Arctic sea ice that scientists believe will happen by midcentury is being caused by us.*

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Ebola response in rural Sierra Leone not yet rapid enough

REUTERS   by    Emma Farge                                                                                                 Dec. 21, 2014       
KOIDU, Sierra Leone -- The rapid response team has arrived and the chaos is easing, but medics in a remote Sierra Leonean district are struggling to control a local Ebola outbreak when it's too late to nip it in the bud.

Health workers rest outside a quarantine zone at a Red Cross facility in the town of Koidu, Kono district in Eastern Sierra Leone December 19, 2014. Credit: Reuters/Baz Ratner

A deployment of medical workers and equipment to Kono District has been the fastest so far in Sierra Leone, a country with nearly half the total Ebola cases,- under a strategy of tackling epidemic hotspots before they get too big.

But officials say responses need to be yet faster to fight the fever that has killed more than 7,000 people across West Africa.

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Opinions: Sierra Leone’s crisis deepens as doctors die of Ebola

WASHINGTON POST OP-ED by Claudena Skran                                                                      Dec. 20, 2014

No evacuation plane to the United States or Europe awaited Dr. Thomas Rogers in early December when he fell ill with the Ebola virus in Sierra Leone.

Instead, the highly trained physicianstruggled to be admitted to one of the few Ebola treatment centers in the West African country. After finally securing a bed, Rogers died on Dec. 5 , sharing the tragic course of the Ebola epidemic with his countrymen.

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Ebola Should Be Easy to Treat

NEW YORK TIMES SUNDAY REVIEW   by Jeffrey Gettleman                                            Dec. 21, 2014

FREETOWN, Sierra Leone --
...Ebola, however much some of its symptoms conjure up a horror film, is usually shockingly simple to treat. The virus is swift and ruthless, hideous and creepy, causing some patients to have bloody vomit, bloody diarrhea or even — in severe cases — bloody eyeballs. Ebola is one of the handful of viruses than can trigger a hemorrhagic fever, with internal bleeding, but in most cases the biggest threat is dehydration, which can be addressed by clean water and basic drugs.

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S Leone to withdraw Somalia troops over Ebola

African Union blocks troops rotation over Ebola fears, forcing Sierra Leone to withdraw its 850 soldiers from Somalia.

ALJAZERA     by     Hansa Mohamed                             Dec. 21, 2014

Sierra Leone is withdrawing its troops from Somalia after the African Union blocked the West African country from rotating its soldiers over fears for the Ebola virus.

Sierra Leone sent 850 troops to Somalia for a 12-month deployment to fight the al-Qaeda-linked rebel group, al-Shabab, in Somalia in 2013.

Their rotation was delayed after a group of 800 soldiers, who were waiting to replace their comrades in Somalia, were quarantined after one of the soldiers was tested positive for Ebola.

"They have to go. We wish they could have stayed but they have been here long. And there is no rotation possible because of the nature of the situation," Maman Sidou, the AU's special representative for Somalia said during a farewell event for the troops held in the port city of Kismayo on Friday.

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NHS Ebola staff ‘insulted’ by UK travel ban

Volunteers’ anger at restrictions imposed on their return home from west Africa

THE GUARDIAN by Tracy Mcveigh                                                                                   Dec. 21, 2014

As the latest of the six British-built Ebola treatment centres in west Africa admitted its first three patients this weekend, some of the volunteer NHS staff working there over Christmas said they felt insulted by a draconian ramping up of the protocols they have been told they will have to follow when they return to the UK.

 

A British health worker puts on protective clothes at a Red Cross clinic in eastern Sierra Leone. Photograph: Baz Ratner/Reuters

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Liberian voter turnout low as Ebola overshadows senate election

REUTERS  by James Harding Giahyue                                                                                     Dec. 20, 2014

MONROVIA--Turnout for Liberian parliamentary elections on Saturday appeared to be low as concerns about Ebola kept many voters at home.

 

Bystanders read the headlines illustrating the battle over the holding of elections in Liberia amid the Ebola crisis at a street side chalkboard newspaper in Monrovia, December 2, 2014. Credit: Reuters/James Giahyue

Polling stations were largely empty after voting began at 8 a.m. (3.00 a.m. ET) in the seafront capital Monrovia, with voters occasionally drifting in, despite precautions put in place by the National Elections Commission (NEC).

Staff with temperature guns at polling stations checked voters for any signs of the hemorrhagic fever, which is spread via bodily fluids. Voters were obliged to wash their hands with chlorine solution, to stand at least three feet apart in the queue, and bring their own pens to mark the ballot paper, officials said.

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