ASSOCIATED PRESS by Clarence Roy-Macaulay                                                 Dec. 18, 2014

 ...Dr. Victor Willoughby tested positive for Ebola on Saturday and was being treated at a clinic near the capital run by the medical charity Emergency, said Dr. Brima Kargbo, the country's chief medical officer....

The 67-year-old died Thursday morning, just hours after an experimental drug arrived in the country for him. The arrival of ZMAb, developed in Canada, had raised hopes for Willoughby's survival. But he died before a dose could be administered, said Kargbo. ZMAb is related to ZMapp, another experimental drug that has been used to treat some Ebola patients. The drugs' efficacy in treating Ebola has not yet been proven....

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http://abcnews.go.com/Health/wireStory/11th-sierra-leonean-doctor-dies-ebola-27684697

A Sierra Leonean boy looks out of a doorway in Freetown, Sierra Leone, December 16, 2014. 
Credit: Reuters/Baz Ratner

reuters.com - by Emma Farge - December 17, 2014

(Reuters) - Ebola centres in Sierra Leone overflowed on Wednesday as health workers combed the streets of the capital Freetown for patients, after the government launched a major operation to contain the epidemic in West Africa's worst-hit country.

President Ernest Bai Koroma said on national television that travel between all parts of the country had been restricted as part of "Operation Western Area Surge", and public gatherings would be strictly controlled in the run-up to Christmas.

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Interviews with experts on what to take away from the devastation of the disease.

THE ATLANTIC   by Julie Beck                                                                                                 Dec. 17, 2014

...While some in the Western media criticized West Africans' fear of health workers and resistance to public-health measures, the United States got a small taste of Ebola panic when Thomas Eric Duncan became the first case diagnosed in the country in September, followed by three other cases this fall. Duncan was the only patient to die in the U.S., and the panic died down quietly.

A front-line report from Sierra Leone examines efforts to change hearts and minds in West Africa’s villages.

NATURE   by Erika Check Hayden                                                                             Dec. 17, 2014

Bombali District, Sierra Leone --Since September, the Ebola virus has stalked the villages and towns along the Kamakwie–Makeni Road, a rutted, red-dirt track that serves as the main artery for a string of villages in the western part of Sierra Leone’s Bombali District.

Yeli Sanda, a village just a few kilometres outside the district’s capital city of Makeni, was the first place to be hit. Over the following months, more than 40 people in the settlement of about 700 became infected; 22 died. In November, the virus infected a woman in Tambiama, about 11 km up the road. A friend who visited her acquired the virus and carried it another 1.5 km to the village of Mayata. She and at least five others there have died.

                CDC Morbidity and Mortality Weekly Report (MMWR)                                                                   

 by Aimee Summers, PhD1,2, Tolbert G. Nyenswah, MPH 3, Joel M. Montgomery, PhD2,4, John Neatherlin, MPH2,4,       Jordan W. Tappero, MD                                                                                                              Dec. 16, 2014

...The Ebola epidemic in Liberia presents unique challenges not only from its spread into crowded urban environments (10) but also its occurrence in remote communities. As in urban counties, county and district health teams in rural counties with remote regions need adequate training in 1) case reporting; 2) case investigation; 3) case management; 4) contact tracing; 5) safe burials; 6) safe collection, processing, and transport of blood specimens for testing; and 7) development of a county-level incident management system.

U.S. NEWS AND WORLD REPORT HEALTH TODAY   by   Dennis Thompson                            Dec. 17, 2014

A screening test has identified more than 50 drugs that could be helpful in treating people with Ebola, researchers report.

"These drugs are all approved (by the FDA) so they could be deployed quickly if follow-up research proves that they are effective," said study author Adolfo Garcia-Sastre, director of the Global Health and Emerging Pathogens Institute with the Icahn School of Medicine at Mount Sinai in New York City.

The study was published online Dec. 17 in the journal Emerging Microbes and Infections.

The screening test involves a laboratory-engineered fake Ebola virus. The fake virus contains two proteins from the deadly pathogen, but does not include the infectious genetic material that makes Ebola so dangerous, Garcia-Sastre said.

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http://health.usnews.com/health-news/articles/2014/12/17/screening-test-finds-drugs-that-show-promise-against-ebola

Read Emerging Microbes and Infections paper.

http://www.nature.com/emi/journal/v3/n12/full/emi201488a.html

UNITED NATIONS NEWS CENTRE                                                                                            Dec. 16, 2014
Response workers battling the Ebola outbreak in West Africa will receive “hazard pay” for the first time in Sierra Leone using mobile money because “unless there is a certain element of incentives, or danger pay, it’s very difficult to attract and retain people,” the United Nations Development Programme (UNDP) announced today.

Ambulance depot near an emergency response centre, in Freetown, Sierra Leone. Ambulances and drivers have to be disinfected after each trip carrying suspected Ebola cases. UN Photo/Martine Perret

“One of the most difficult things about tackling the Ebola crisis is in the area of human resources,” said Sudipto Mukerjee, UNDP’s Country Director for Sierra Leone. “You can construct a treatment centre in a couple of months. You can construct a community care centre in two to three weeks. But getting trained people to come and run them has been a major challenge.”

The transition from direct cash to an electronic solution will help to improve overall efficiency, timeliness and security of payments for Ebola response workers, Mr. Mukerjee said.

BBC                                                                                                                         Dec. 17, 2014

Sierra Leone is due to mount house-to-house searches in the capital Freetown to find hidden cases of Ebola.

President Ernest Bai Koroma also said that Sunday trading would be banned and travel between districts restricted.

The measures come after the authorities banned all public celebrations of Christmas and New Year in a bit to tackle the virus...

In his statement, President Koroma said the searches aimed to "break the chain of transmission", the AFP news agency reported.

He added: "Do not hide the sick".
http://www.bbc.com/news/world-africa-30511208?utm_source=December+17+2014+EN&utm_campaign=12%2F17%2F2014&utm_medium=email

The temperatures so far in 2014 compared to the top 5 warmest years on record.
Click image to enlarge. Credit: NOAA

Update: Ebola Virus Disease Epidemic — West Africa, December 2014

CDC                                                                                                                         Dec. 16, 2014

...There were 4,281 new Ebola cases reported during the 4-week period of November 9–December 6, compared with the 2,705 new cases reported during the 3-week period of October 19–November 8.. Cases were widely distributed geographically among districts in all three countries, with the prefecture of Mamou in Guinea reported to be newly affected.

During both periods, counts of reported Ebola cases were highest in the area around Monrovia, including Grand Cape Mount, Liberia; the Western Area and northwest districts of Sierra Leone, particularly Bombali and Port Loko; and Conakry, Guinea .

Read Complete report.
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm63e1216a1.htm?s_cid=mm63e1216a1_x

Why saving the environment can help prevent it

TIME MAGAZINE     by Alexandra Sifferlin                                                                         Dec. 16, 2014

The global community cannot withstand another Ebola outbreak: The World Bank estimates the two-year financial burden price tag of the current epidemic at $32.6 billion. Unfortunately, the virus has revealed gaping holes in our preparedness for major infectious disease epidemics. Because of these, plus the urbanization of rural communities and globalization of travel and trade, more of these epidemics are expected.

In a new report from the EcoHealth Alliance published in the journal Proceedings of the National Academy of Sciences (PNAS), experts estimate that the world will see about five new emerging infectious diseases each year and that we need new prevention strategies to cut economic losses.

WIRED             by Erika Check Hayden                                                                                         Dec. 16, 2014

BO, Sierra Leone—Morning rounds have just begun at an Ebola treatment center here in the city of Bo, in central Sierra Leone.

An Ebola management center run by Doctors Without Borders in Bo, Sierra Leone.  Erika Check Hayden

The patients who are able shuffle out of a tent towards two layers of chain-link fence that separate them from the outside—2 meters minimum distance. Some clutch bottles of water, bright orange soda, or foil-wrapped nutritional bars. A woman in an orange printed wrap skirt lags behind the others, struggling to slide a sandal on to her foot. She came here in bad shape with her husband and three children, but she is improving; she was recently taken off intravenous fluids....

NATIONAL PUBLIC RADIO  by Michaeleen Doucleff                                                               Dec. 16, 2014

Speed. That's key to ending the Ebola epidemic, says the director of the U.S. Centers for Disease Control and Prevention.

Dr. Thomas Frieden is visiting West Africa this week to figure out how to reduce the time it takes to find new Ebola cases and isolate them.

Otherwise, Ebola could become a permanent disease in West Africa.

"That's exactly the risk we face now. That Ebola will simmer along, become endemic and be a problem for Africa and the world, for years to come," Frieden tells NPR. "That is what I fear most."

NEW YORK TIMES    by Donald G. McNeil, Jr.                                                                 Dec. 16, 2014

Transmission of the Ebola virus occurs mostly within families, in hospitals and at funerals, not randomly like the flu, Yale scientists said Tuesday, and far fewer cases go unreported than has previously been estimated.

Survivors of the Ebola virus pose for a picture outside a clinic near Tubmanburg, October 15, 2014.
REUTERS/James Giahyue

CLICK HERE - RESEARCH - To hasten Ebola containment, mobilize survivors

uk.reuters.com - by Magdalena Mis - December 10, 2014

LONDON (Thomson Reuters Foundation) - Thousands of Ebola survivors with little to no risk of re-infection are critical to controlling the epidemic and training them has the potential to save thousands of lives and decrease the spread of the virus, experts said on Wednesday.

Survivors have developed immunity and are effectively the only people in the world protected from the virus, which could allow them to care for the sick without risking their lives, said experts in the International Journal of Epidemiology.

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