In a major setback, Merck to stop developing its Covid-19 vaccines - STAT Merck announced it is stopping development of both of the current formulations of the Covid-19 vaccines the company was working on. Matthew Herper STAT

Merck said Monday it will stop developing both of the current formulations of the Covid-19 vaccines the company was working on, citing inadequate immune responses to the shots.

.... Since the nation began distributing vaccines more than a month ago, it has moved far more slowly than officials hoped and has been stymied by widespread logistical problems.

But West Virginia has stood out for its success in getting people vaccinated. About 9 percent of all West Virginians have received a first dose of the coronavirus vaccine, a larger segment than in every state but Alaska and double the rate of some. No state has given a larger share of its residents second doses, a crucial step to securing the best chance at immunity.

Moderna says it's working on Covid booster shot for variant in South Africa, says current vaccine provides some protection Berkeley Lovelace Jr. CNBC

Moderna said Monday it’s accelerating work on a Covid-19 booster shot to guard against the recently discovered variant in South Africa.

Why Vaccines Alone Will Not End the Pandemic New estimates suggest the vaccine rollout is no match for the severity of the U.S. outbreak, and stricter social distancing measures are needed to reduce infections. nytimes

The coronavirus pandemic in the United States has raged almost uncontrollably for so long that even if millions of people are vaccinated, millions more will still be infected and become ill unless people continue to wear masks and maintain social distancing measures until midsummer or later, according to a new model by scientists at Columbia University.

Biden health officials express concern about short-term vaccine supply crunch “I think that the supply is probably going to be the most limiting constraint early on," the CDC director said. Jesse Naranjo POLITICO

Top Biden administration health officials on Sunday expressed concern about limited vaccine supplies but offered measured optimism that the worse-than-expected rollout would be improved, while warning that the current crunch for doses posed a pressing threat.

2 in 5 Americans live where COVID-19 strains hospital ICUs Straining to handle record numbers of COVID-19 patients, hundreds of the nation's intensive care units are running out of space and supplies and competing to hire temporary traveling nurses at... AP NEWS

Straining to handle record numbers of COVID-19 patients, hundreds of the nation’s intensive care units are running out of space and supplies and competing to hire temporary traveling nurses at soaring rates. Many of the facilities are clustered in the South and West.