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Proposed Ebola biobank would strengthen African science

NATURE by Erika Check Hayden                                                                             Aug. 10, 2015
As West Africa’s Ebola outbreak winds down, an effort is under way to make the best use of the tens of thousands of patient samples collected by public-health agencies fighting the epidemic.  Samples from the Ebola epidemic in West Africa are held by public-health agencies in the region and abroad. Daniel Berehulak/NYT/Redux/Eyevine

On 6–7 August, the World Health Organization (WHO) convened a meeting in Freetown, Sierra Leone, to discuss how to establish a biobank for up to 100,000 samples of blood, semen, urine and breast milk from confirmed and suspected Ebola patients, as well as swabs taken from the bodies of people who died from the virus. Held by health agencies in both West Africa and the West, the samples could be valuable in understanding how the current Ebola crisis evolved, preparing for future outbreaks and developing public-health research capacity in a region that depends on outside experts.

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China to build highway for Liberia as part of Ebola recovery aid

REUTERS                                                                                                  Aug. 9, 2015

MONROVIA -- China will build a new coastal highway for Liberia as part of its aid to the country recovering from an Ebola epidemic, Liberia's foreign minister said on Sunday.

He was speaking at a news conference with China's Foreign Minister Wang Yi who is visiting Liberia, Guinea and Sierra Leone, the countries hardest hit by the epidemic.

Liberia's existing coastal route is vital for commerce as the country rebuilds after a civil war that ended in 2003. It connects the capital to the border with Ivory Coast via the port city of Buchanan, where exports of exports of iron and timber pass through, but much of the road is unpaved.

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http://www.reuters.com/article/2015/08/09/us-health-ebola-liberia-china-idUSKCN0QE0OV20150809

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Ebola terrified us a year ago. What did it teach us about West Africa?

WASHINGTON POST  by

“If it bleeds, it leads.” That’s the cliché in journalism that describes why a certain kind of tragedy tends to dominate the news cycle. One year ago today, the World Health Organization declared Ebola an “international health emergency.” But today, coverage of West Africa is beginning its drift into media disinterest as Ebola cases wane. International attention has now largely disappeared along with the sight of biohazard suits and ambulances.....

But it would be a mistake to celebrate victory over Ebola and return to the pre-outbreak status quo. The lessons of Ebola reach beyond the preparedness of West African health systems to confront crises, touching on issues that have been critical for the region in recent years: peace, security and how responsive governments are to society’s most vulnerable members. These lessons must be understood before a post-outbreak aid and development agenda is designed....

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Ebola Survivors Face Lingering Pain, Fatigue and Depression

NEW YORK TIMES  by Denis Grady                               Aug. 8, 2015

The Ebola outbreak that started more than a year ago seems to be waning at last. But now, West Africa faces another difficulty: More than 13,000 people survived the virus, and many have lingering health problems, psychological troubles like depression and post-traumatic stress disorder, and worries about returning to work to feed themselves and what is left of their families.

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How to Beat the Next Ebola

submitted by George Hurlburt

             

Graves dug in Freetown, Sierra Leone, to cope with those dying from Ebola in late 2014.  Mads Nissen/Panos

The world is ill-prepared for the next epidemic or pandemic. But the horror of the Ebola outbreak in West Africa may drive change.

nature.com - by Declan Butler - August 5, 2015

If there was one point last year when public-health experts held their breath, it was when a Liberian man infected with Ebola virus flew to Lagos, Nigeria, in July. Ebola was already raging uncontrolled through impoverished countries in West Africa, killing half of those it infected. Now a vomiting man had carried it straight to the heart of Africa's largest megacity — with 21 million inhabitants, many of whom live in slums. Experts were horrified at the prospect that the virus might rip through the city — and then, because Lagos is an international travel hub, spread farther afield.

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Physicians: Global Vaccine Development Fund Could Save Billions

PHARMACEUTICAL PROCESSING by  Princeton University, Woodrow Wilson School of Public and International Affairs   Aug. 6, 2015

Ebola is a preventable disease, and yet a safe and effective vaccine has not been deployed. As with many vaccines, financial barriers persist: pharmaceutical companies see high costs with limited market potential, and government support is lacking. But there may be a solution to this vaccine crisis with the ability to save at-risk populations, according to a perspective piece written by physicians based at Princeton University, University of Pennsylvania and the Wellcome Trust.

The article, published in the New England Journal of Medicine, proposes the creation of a $2 billion global vaccine-development fund - supported by governments, foundations and pharmaceutical companies - that would carry promising vaccines through development to deployment. With initial support, the global vaccine fund could help make vaccines available for emergency use.

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What ‘100 Percent Effective’ Means for That Ebola Vaccine

Analysis
WIRED.COM by Katie M. Palmer                                                            Aug. 4, 2015

Last week, the medical journal the Lancet published preliminary results on the efficacy of an Ebola vaccine in Guinea, and everybody got really excited—especially about one particular figure. The vaccine, the results suggested, was 100 percent effective at protecting against Ebola, a thrilling prospect in the face of an epidemic that has killed more than 11,000 people. ...

But that number probably means less than you think it does. It’s based on incomplete data, so it doesn’t have the statistical clout it should. And it never will. Based on the vaccine’s early success, the trial’s runners decided that all participants in the study should get it immediately after exposure. That’s a perfectly reasonable, humane reaction, but it also means that the researchers will never be able to collect better data on the vaccine’s efficacy, which is what regulators look for when they’re deciding to approve a drug. In other words, the vaccine’s early success could make it harder for people to get it down the line.

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Arktek Passive Vaccine Storage Device - P6

      

From watching the video in the link below, the Arktek vaccine cold storage device is also known as the P6 . . .
http://www.intellectualventures.com/inventions-patents/our-inventions/vaccine-cold-chain-device/

The P6 is not just a container, but an innovative high-tech device.  It is designed to keep vaccines at the appropriate temperatures for a month or more with repeat vaccine retrievals and no need for electricity (using just one initial batch of ice).  The device also has built-in communications and monitoring capability.  The P6 units are able to send live updates, including the units’ GPS positions viewable on interactive maps, the number of days since fresh ice had been added, temperature, and more.  Here are the details . . .
http://www.intellectualventureslab.com/invent/a-story-of-invention-the-passive-vaccine-storage-device

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More than 70,000 children born during the Ebola outbreak in Liberia at risk of exclusion if not registered, warns UNICEF

UNICEF PRESS OFFICE                                                 July 31, 2015

MONROVIA, Liberia -- UNICEF is supporting a drive by the Liberian Government to register more than 70,000 children whose births were not recorded during the Ebola crisis, leaving them vulnerable to marginalization and exclusion.

Birth registrations in 2014 and 2015 dropped sharply from pre-Ebola levels, according to Ministry of Health data. In 2013, before the onset of the virus, the births of 79,000 children were registered. In 2014, when many health facilities had closed or had reduced services due to the Ebola response, the number of registrations fell to 48,000 – a 39 per cent decrease over the previous year.

Just 700 children are reported to have had their births registered between January and May 2015. 

 

                                                                               © UNICEF/UNI190366/Grile Three month old Success Sumois,     strapped to her mother’s back, waits to be registered through the mobile birth registration team at the Totota Clinic in Liberia.

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WHO: Trials Show New Ebola Vaccine is 'Highly Effective'

            

On March 23, 2015, Medecins Sans Frontieres (Doctors Without Borders) together with the World Health Organization started a clinical trial in Guinea to test the safety, efficacy and capacity substance to provoke an immune response of the anti-Ebola vaccine rVSV-EBOV.

cnn.com - by Laura Smith-Spark - July 31, 2015

(CNN) A newly developed vaccine against the deadly Ebola virus is "highly effective" and could help prevent its spread in the current and future outbreaks, the World Health Organization said Friday.

Trials of the single-dose VSV-EBOV vaccine began in March in Guinea -- one of three West African nations at the center of the outbreak -- and have shown such promise that this week it was decided to extend immediate vaccination to "all people at risk" after close contact with an infected person, a WHO news release said.

"This is an extremely promising development," said Dr. Margaret Chan, the body's director general.

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