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Arktek Passive Vaccine Storage Device - P6

      

From watching the video in the link below, the Arktek vaccine cold storage device is also known as the P6 . . .
http://www.intellectualventures.com/inventions-patents/our-inventions/vaccine-cold-chain-device/

The P6 is not just a container, but an innovative high-tech device.  It is designed to keep vaccines at the appropriate temperatures for a month or more with repeat vaccine retrievals and no need for electricity (using just one initial batch of ice).  The device also has built-in communications and monitoring capability.  The P6 units are able to send live updates, including the units’ GPS positions viewable on interactive maps, the number of days since fresh ice had been added, temperature, and more.  Here are the details . . .
http://www.intellectualventureslab.com/invent/a-story-of-invention-the-passive-vaccine-storage-device

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WHO: Trials Show New Ebola Vaccine is 'Highly Effective'

            

On March 23, 2015, Medecins Sans Frontieres (Doctors Without Borders) together with the World Health Organization started a clinical trial in Guinea to test the safety, efficacy and capacity substance to provoke an immune response of the anti-Ebola vaccine rVSV-EBOV.

cnn.com - by Laura Smith-Spark - July 31, 2015

(CNN) A newly developed vaccine against the deadly Ebola virus is "highly effective" and could help prevent its spread in the current and future outbreaks, the World Health Organization said Friday.

Trials of the single-dose VSV-EBOV vaccine began in March in Guinea -- one of three West African nations at the center of the outbreak -- and have shown such promise that this week it was decided to extend immediate vaccination to "all people at risk" after close contact with an infected person, a WHO news release said.

"This is an extremely promising development," said Dr. Margaret Chan, the body's director general.

(READ COMPLETE ARTICLE)

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UN Ebola mission winds down, WHO takes reins in West Africa

ASSOCIATED PRESS by MARIA CHENG and RAPHAEL SATTER   July 31, 2015

LONDON — The United Nations Mission for Ebola Emergency Response is officially winding down Friday, handing its leadership role and senior staff to the Geneva-based World Health Organization as efforts to contain the deadly virus continue.

"We have reached an important milestone in the global Ebola response," U.N. Secretary-General Ban Ki-moon said in a statement Friday, while noting that that crisis "is not yet over."

The Ebola mission, also called UNMEER, was established last year as WHO struggled to get a handle on an outbreak that has killed more than 11,000 people, mainly in Guinea, Sierra Leone and Liberia. WHO had been strongly criticized for fumbling its response to the epidemic, and the creation of UNMEER was widely seen as a rebuke to its leadership.

Speaking to reporters Friday, UNMEER chief David Nabarro said he had seen signs that WHO had already absorbed some of the lessons of the Ebola disaster, recovering its coordination role in West Africa and deploying more 1,000 staffers to the field.

Read complete story.
http://www.seattlepi.com/news/medical/article/WHO-works-to-reform-itself-after-fumbling-Ebola-6416880.php

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Ebola death in Sierra Leone leads to mass quarantine

DEUTSCHE WELLE    by Susan Houlton                         July 31, 2015
 
A village in northern Sierra Leone has been placed under quarantine after a post-mortem test revealed a man had died from Ebola. Several hospitals failed to recognize him as a potential victim of the disease.


Earlier this week the World Health Organization (WHO) announced the fewest weekly Ebola infections for over a year in West Africa. However the WHO also said it was bracing for a significant new outbreak in Sierra Leone, which alongside Guinea and Liberia, is one of the worst affected countries.

In the week up to Sunday 26 July, there were four confirmed cases in Guinea and three in Sierra Leone. Those three included a patient who died after travelling from the capital Freetown to the northern district of Tonkolili. He was described by the WHO as posing "a substantial risk of further transmission." The patient had only been confirmed Ebola-positive after post-mortem testing....

According to Hassan Abdul Sesay, a member of parliament from the region where the patient died, the man had traveled to his home village to mark the end of the Muslim holy month of Ramadan.
Read full story.

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The Individualised versus the Public Health Approach to Treating Ebola

PLOS/Medicine   by  Tom H. Boyles                            July 28, 2015

The mortality rate for patients with Ebola virus disease (EVD) in West Africa is approximately 65% [1]. There are no published figures for high-resource settings, but media sources and individual case reports suggest it is much lower and approaches 0% for those who receive this level of care from the beginning of their illness.

In their article “Ebola Viral Disease: Experience and Decision Making for the First Cases outside of Africa,” David Stephens and colleagues give insight into the care that can be provided when available resources are not the limiting factor [2]. They describe the decision to open the Serious Communicable Diseases Unit (SCDU) of Emory University Hospital (EUH) when two United States patients contracted EVD while working in West Africa. Using a large specialist team, they provided high-quality care in a safe working environment and disseminated their knowledge and experience widely.....

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How West Africa is ramping up food security after Ebola outbreak

Countries in West Africa and the international community are teaming up to fight Ebola's  lingering effects on food security and agriculture.

Volunteers distribute food at a World Food Programme storage center in Monrovia October 16, 2014. Almost a year after the Ebola outbreak garnered strength in West Africa, countries in that region and the international community are teaming up to fight the disease's lingering effects on food security and agriculture. James Giahyue/Reuters/File

CHRISTIAN SCIENCE MONITOR by Clare Algozin                                    July 29, 2015

As the death toll of EVD rose, West African countries began to experience labor shortages, and many fields of crops went unharvested, according to U.N. Food and Agriculture Organization (FAO). As part of the measures to prevent the spread of EVD, many West African governments established quarantine zones and restricted the movements of people.

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WHO - Ebola Situation Report - 29 July 2015

                                          

who.int - July 29, 2015 - SUMMARY - (See Links to Situation Reports Below)

There were 7 confirmed cases of Ebola virus disease (EVD) reported in the week to 26 July: 4 in Guinea and 3 in Sierra Leone. This is the lowest weekly total for over a year, and comes after 8 consecutive weeks during which case incidence had plateaued at between 20 and 30 cases per week. Although this decline in case incidence is welcome, it is too early to tell whether it will be sustained. There have been several high-risk events in both Guinea and Sierra Leone in the past 14 days, and past experience has shown that it can take a single high-risk case or missed contact to spark a new cluster of cases. In addition, there are over 2000 contacts still within their 21-day follow-up period in Guinea, Liberia, and Sierra Leone, representing a substantial residual risk of further cases. Refinements to the response continue to yield improvements, with recent weeks seeing a higher proportion of cases arising from contacts and a lower proportion of cases identified post-mortem than at any time previously, but the continued occurrence of high-risk transmission events means that an increase in case incidence in the near term is a strong possibility.

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Addressing therapeutic options for Ebola virus infection in current or future outbreaks

AMERICAN SOCIETY FOR MICROBIOLOGY  by Azizul Haque and others                                July  27, 2015

 Ebola virus can cause severe hemorrhagic disease with high fatality rates. Currently, no specific therapeutic or vaccine has been approved for treatment and prevention of Ebola infection of humans. Although the number of Ebola cases has fallen in the last few weeks, multiple outbreaks of Ebola virus infection and the likelihood of future exposure highlight the need for development and rapid evaluation of pre- and post-exposure treatments.

In this manuscript we briefly review the existing and future options for anti-Ebola therapy, based on the data coming from rare clinical reports, studies on animals and results from in vitro models....

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http://aac.asm.org/content/early/2015/07/21/AAC.01105-15.short?rss=1

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Sierra Leone President unveils Ebola "battle plan"

AFP    July 26, 2015
Freetown  - Sierra Leone's President Ernest Bai Koroma has unveiled a post-Ebola "battle plan" to help the west African country turn the page on the devastating epidemic.


Sierra Leone's President Ernest Bai Koroma speaks at an International Ebola Recovery Conference on July 10, 2015 at the United Nations headquarters in New York (AFP Photo/Eduardo Munoz Alvarez)

"Beyond the immediate nine-month recovery period, we will commence a two-year plan during which we must resolve to restore Sierra Leone to the path to prosperity," Koroma said in a statement released Friday.

"We will work to reinvigorate the private sector as a source of growth, create jobs and livelihoods in our economy," he said, emphasising the need to improve roads and market access.

Read complete story.
http://news.yahoo.com/sierra-leone-president-unveils-post-ebola-battle-plan-175118537.html

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Ebola study notes afebrile patients, calls into question WHO criteria

CENTER FOR DISEASE RESEARCH AND POLICY        July 24, 2015

(Also scroll down for: Ebola case definition quandary; Public health worker Ebola unease)

Researchers found that the World Health Organization (WHO) Ebola case definition has a specificity of only 31.5%, and they noted that 9% of Ebola patients reported neither a fever nor any Ebola risk exposure, calling into question WHO norms, according to a large study yesterday in The Lancet Infectious Diseases.

Researchers from Britain and Sierra Leone analyzed data on 850 suspected and 724 lab-confirmed Ebola patients who presented to the holding unit of Connaught Hospital in Freetown from May 29 to Dec 8, 2014. Fever or history of fever (n=599, 83%), intense fatigue or weakness (495, 68%), vomiting or nausea (365, 50%), and diarrhea (294, 41%) were the most common presenting symptoms in suspected cases.

Based on data from these patients, the investigators found the sensitivity of the WHO case definition to be 79.7%, which means about 20% of true Ebola cases would be missed (false-negatives). They found the specificity of the case definition to be 31.5%, which means 68.5% of patients who would be selected for admission would not actually have Ebola virus disease (false-positives).

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