CENTER FOR INFECTIOUS DISEASE AND POLICY RESEARCH     by Lisa Schnirring                                 Jan. 9, 2015

The next steps in testing Ebola vaccines as well as a picture of how they might be used in West Africa's outbreak region became clearer today as officials from the World Health Organization (WHO) shared the outcome of yesterday's (Thursday's) high-level meeting in Geneva.

Large phase 3 trials in West Africa's outbreak setting will be next up to see if the vaccines work, with the studies designed to collect more safety data, a task usually covered in phase 2 trials, experts involved in the meeting said today at a WHO media telebriefing. However, as Ebola infections drop off in the outbreak region, scientists face a closing window of opportunity to see how the vaccines perform in a real-life setting.

Experts also signaled a possible role for two Ebola vaccine formulations: a single-dose vaccine providing shorter-term immunity that could be used to tamp down Ebola flare-ups and a prime-boost vaccine that may provide more durable immunity and could be used for other immunization strategies.

Latest surveys point to declines in employment, food insecurity, and long-term welfare concerns

THE WORLD BANK                                                       Jan. 12, 2015

WASHINGTON-- The socio-economic impacts of Ebola in Liberia and Sierra Leone are far-reaching and persistent, according to two new World Bank Group reports. Both countries continue to experience job losses, despite their differing health outlooks. These impacts have not been limited to the areas where infections have been the highest, which points to economy-wide slowdowns. As a result, many households have been forced to take short-term actions to cope, which can have substantial long-term effects on welfare.

“The Ebola virus itself must be eradicated- this is the number one priority,” said Ana Revenga, Senior Director for Poverty at the World Bank Group. “But its socio-economic side effects put the current and future prosperity of households in Liberia and Sierra Leone at high risk. We must pay careful attention to those who are most vulnerable to both health and economic shocks, and ensure that they are supported throughout and after the crisis.”

REUTERS                                                                                    Jan. 12, 2015

LONDON- A British nurse diagnosed with Ebola last month is recovering and is no longer in a critical condition, the London hospital treating her said in a statement on Monday.

Pauline Cafferkey, a 39-year-old nurse who normally works at a Scottish health center, became the first person to be diagnosed with the disease in Britain after contracting it in Sierra Leone where she was volunteering at an Ebola clinic.

"Pauline Cafferkey is showing signs of improvement and is no longer critically ill," the statement from the Royal Free Hospital said. "She remains in isolation as she receives specialist care for the Ebola virus."

Cafferkey is being treated with blood plasma from an Ebola survivor and an unnamed experimental anti-viral drug, the hospital has said.

Read complete story.
http://news.yahoo.com/british-ebola-patient-recovering-no-longer-critical-says-141357956.html;_ylt=AwrBEiLsF7RUKgYAww_QtDMD

WHO and medical staff at the Ebola management site in Kailahun District, Sierra Leone
WHO/J. Caminade

Kailahun district in eastern Sierra Leone was one of the country’s first hotspots in the Ebola outbreak, at its peak reporting more than 80 new cases per week in late June 2014. With the assistance of WHO and partners, combined with the close involvement of community leaders, the district has managed to beat the disease and has reported no new cases for several weeks. There is no room for complacency however. Community teams and health workers are on high alert and are ready to react quickly to any possible new infection.

who.int - December 2014