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" 10 drugs that could stop Ebola "

FIERCE BOIOTECH RESEARCH                       Oct. 14, 2014
By Emily Mullin

Before the current Ebola outbreak, the virus had only appeared in Africa in fits and starts since its discovery in 1976, receding back into the jungle almost as quickly as it arrived. This relative rarity and the swiftness with which the disease kills its victims has, up until now, made Ebola an unattractive--not to mention daunting--prospect for drug developers. As a result, no approved drugs or vaccines against Ebola exist.

...the current situation in West Africa... has prompted the World Health Organization to call on international government agencies and the pharmaceutical industry to work together to speed up the development of promising therapies for experimental use for those most at risk of contracting the disease, which causes severe hemorrhagic fever.

Now, a handful of players are racing to get a treatment or vaccine to patients as quickly as possible, even though these drugs remain largely untested in humans.... 

Here is a list of organizations that are in the global spotlight right now with their investigational Ebola program

See full story and list

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Head of World Bank Makes Ebola His Mission

NEW YORK TIMES                                                                                        OCT. 14, 2014

By                         

During a tense discussion, Dr. Jim Yong Kim, the World Bank president, spoke sharply to Dr. Margaret Chan, the head of the World Health Organization, the agency in charge. You have the authority to act in this emergency, he told her, according to people familiar with the meeting, “so why aren’t you doing it?”

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Facebook Founder Mark Zuckerberg Kicks in $25 Million for Ebola

NBC NEWS                                                            OCT. 14, 2014

Facebook founder Mark Zuckerberg and his wife announced Tuesday they are donating $25 million to the U.S. Centers for Disease Control foundation to fight the Ebola crisis that has killed more than 4,440 people in west Africa.

"We need to get Ebola under control in the near term so that it doesn't spread further and become a long term global health crisis that we end up fighting for decades at large scale, like HIV or polio," Zuckerberg, who is worth $32 billion, said in a Facebook post. "We believe our grant is the quickest way to empower the CDC and the experts in this field to prevent this outcome."

The health agency has hundreds of staffers working on Ebola and has sent more than 100 experts to the virus zone — Liberia, Guinea, Sierra Leone and Nigeria. The CDC foundation collects funds for supplies, such as personal protective equipment, ready-to-eat meals, generators, vehicles and motorcycles, and thermal scanners to detect fever.

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The reassuring news in the Texas Ebola cases

WASHINGTON POST

By Todd C. Frankel                         October 14

....The Dallas nurse, 26-year old Nina Pham,who helped treat Thomas Eric Duncan, the Liberian man who was the first person diagnosed with the dreaded disease in the United States became the first – and so far only – person infected by Duncan. In the wake of her infection, U.S. health officials have pledged to review how future Ebola cases are handled.

But the case is also noteworthy for another, potentially positive reason: Nearly 50 people were exposed to Ebola before the nurse, and none of them has been diagnosed with the disease.

This group of neighbors, family members and first responders are being watched carefully by health authorities. They had some degree of close contact with Duncan during the four-day period when he was contagious – from when he started showing Ebola symptoms on Sept. 24 to when the hospital finally admitted him on Sept. 28. They didn’t take any Ebola-specific precautions. They didn’t know he was infected.... Yet, so far, they have not gotten sick. And their 21-day Ebola incubation period started before Pham’s.

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WHO and Partners agree on a common approach to strengthen Ebola preparedness in unaffected countries

Brazzaville, 10 October 2014 - The World Health Organization (WHO) and partner organizations meeting in Brazzaville have agreed on a range of core actions to support countries unaffected by Ebola in strengthening their preparedness in the event of an outbreak.

Building on national and international existing preparedness efforts, a set of tools is being developed to help any country to intensify and accelerate their readiness.

One of these tools is a comprehensive checklist of core principles, standards, capacities and practices, which all countries should have or meet. The checklist can be used by countries to assess their level of preparedness, guide their efforts to strengthen themselves and to request assistance. Items on the checklist include infection prevention control, contact tracing, case management, surveillance, laboratory capacity, safe burial, public awareness and community engagement and national legislation and regulation to support country readiness.

“While we rightly focus on stopping the outbreak in affected countries, we should not forget that all other countries are at risk, albeit at varying levels”, said WHO Regional Director for Africa, Dr Luis Sambo.

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FIVE ITEMS ON EFFORTS TO IMPROVE TRAINING FOR HEALTH WORKERS

Scroll down for the stories and link to CDC check list

CDC TAKES NEW STEPS TO IMPROVE TRAINING FOR HOSPITAL WORKERS

NEW YORK TIMES                   Oct. 13, 2014
By Pam Belluck

The Centers for Disease Control and Prevention is taking new steps to help hospital workers protect themselves, providing more training and urging hospitals to run drills to practice dealing with potential Ebola patients.

In response to the news that a health care worker in Dallas had contracted Ebola, a spokeswoman said the agency would also issue more specific instructions and explanations for putting on and removing protective equipment and would urge nurses and doctors to enlist a co-worker or “buddy” to watch them do so....

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Working with Communities is the Key to Stopping Ebola

who.int - October 2014

When Dr Peter Clements arrived in Lofa County, Liberia eight weeks ago, from the WHO country office in Monrovia, 20-30 patients were arriving at the MSF hospital with Ebola-like symptoms every day. People living in the community were afraid, civil unrest was simmering, and an ambulance and health workers were being targeted

Although UN security advised him not to, Dr Clements traveled the 12 hours over dirt roads to the area nearest the Guinea border. Once there, he walked into the hostile communities and went straight to the chiefs.

“In many years, you have not fought with these people,” he said. “Now you attack them. They are not the enemy, Ebola is the enemy. If we don’t chase Ebola, it will kill us. You have to know Ebola to fight Ebola. Mobilize your people. Let’s get to know Ebola.”

Dr Clements said the key to working with a hostile community is listening first. So he patiently listened to the community to understand their fears, then he started to explain about the virus and how people become sick, and people can prevent themselves.

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Doctors Without Borders Evolves as It Forms the Vanguard in Ebola Fight

Detailed description of Médecins Sans Frontières struggle to counter Ebola

NEW YORK TIMES
By SHERI FINK, ADAM NOSSITER and JAMES KANTER.  OCT. 10, 2014

But it, too, has been overwhelmed by the scale of this disaster. In Sierra Leone, it has been strained by the caseload, though it was wary of a decision by other health and government officials on Friday to treat most patients at home because of a shortage of clinic beds. In Guinea the day before, it reported that its two treatment centers were stretched to the limit....

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Fighting Ebola with Data, Satellites and Drones

Healthcare workers in Sierra Leone spray disinfectant to prevent the spread of the Ebola virus in Kenema, on September 24, 2014.

Image: Healthcare workers in Sierra Leone spray disinfectant to prevent the spread of the Ebola virus in Kenema, on September 24, 2014.

defenseone.com - September 25th, 2014 - Patrick Tucker

Current Centers of Disease Control estimates suggest that the disease could infect more than 1.4 million people by January. To limit Ebola’s spread, researchers need better on-the-ground intelligence about where it’s moving. But the virus’s deadly mortality rate, 70 percent for this strain, makes up-close observation as difficult as gathering data on a deadly human adversary. 

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Here's How Nigeria Beat Ebola

 

  MOTHER JONES                       Oct. 10, 2014

—By

LAGOS -- Nigeria's success in stopping the outbreak could have implications for other countries, including the United States. That's why the Centers for Disease Control and Prevention (CDC) dispatched a team to the country this week to learn what went right.

So how did local and international health authorities curb Ebola in Nigeria while infections have continued to rise dramatically in Liberia, Sierra Leone, and Guinea?

Read full article, with charts and posters

http://www.motherjones.com/politics/2014/10/nigeria-ebola-cdc

An Ebola warning at the Murtala Muhammed International Airport in Lagos

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