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Stopping Pandemic X: DARPA Names Researchers Working to Halt Outbreaks

           

globalbiodefense.com - February 22, 2018

CLICK HERE - DARPA - Pandemic Prevention Platform (P3)

The Defense Advanced Research Projects Agency (DARPA) launched the Pandemic Prevention Platform (P3) program in 2017, with the eventual goal of halting the spread of any infectious disease outbreak before it can escalate into a pandemic . . . 

 . . . In contrast with state-of-the-art medical countermeasures, which typically take many months or even years to develop, produce, distribute, and administer, the envisioned P3 platform would cut response time to weeks and stay within the window of relevance for containing an outbreak.

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Chinese Scientists Find How Bats Carry Viruses Without Getting Sick

xinhuanet.com - Editor: Liu - February 23, 2018

CLICK HERE - Dampened STING-Dependent Interferon Activation in Bats

WASHINGTON, Feb. 22 (Xinhua) -- Chinese scientists have identified the secret of bats that harbor highly pathogenic viruses like Ebola, Marburg and SARS coronavirus but do not show clinical signs of disease.

In a paper published on Thursday in the journal Cell Host & Microbe, scientists at the Wuhan Institute of Virology in China find that in bats, an antiviral immune pathway called the STING-interferon pathway is dampened, so bats can maintain just enough defense against illness without triggering a heightened immune reaction.

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BRIEF: The Virome Project Aims to Prepare Before the Next Pandemic

           

Ebola virus budding from surface of cells, from a scanning electron micrograph.  Image credits: NIAID

CLICK HERE - The Global Virome Project

insidescience.org - by Benjamin Plackett - February 22, 2018

 . . . In an article published in Science magazine today, Daszak and a group of like-minded scientists described a new initiative, called the Virome project, that would identify and catalogue hundreds of thousands of yet-to-be-discovered viruses found in wild animals.

The team estimates that there are about 1.6 million undiscovered virus types and that somewhere between 631,000-827,000 could potentially spill over into humans. The viruses are found mostly in wild mammals.

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Ebola Had Significant Collateral Damage to Liberians' Health

           

A mural announces anti-Ebola sentiment outside a business in Harper, Liberia.  Brad Wagenaar

CLICK HERE - STUDY - The 2014–2015 Ebola virus disease outbreak and primary healthcare delivery in Liberia: Time-series analyses for 2010–2016

After the 2014 outbreak, the population's needs were often unmet in terms of primary care, mother-child health, and immmunizations.

newsroom.uw.edu - by Ashlie Chandler - February 20, 2018

The 2014 Ebola outbreak in West Africa rapidly became the deadliest occurrence of the disease — claiming 4,809 lives in Liberia alone.  Now new research from the University of Washington suggests Ebola's collateral effects on that nation's health system likely caused more deaths than Ebola did directly.

The study, published today in PLOS Medicine, found that it only took four months for Liberia to lose between 35 percent and 67 percent of primary health care services after the  Ebola outbreak began.

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Other Viruses Cause Zika-Like Damage to Fetuses, Study Finds

           

Zika's blood-sucking predator

CLICK HERE - STUDY - Zika virus–related neurotropic flaviviruses infect human placental explants and cause fetal demise in mice

cnn.com - by Susan Scutti - February 18, 2018

In 2016, the US Centers for Disease Control and Prevention confirmed that the Zika virus caused birth defects in babies born to women who had been infected while pregnant. This was the first mosquito-borne disease known to cause birth defects . . . 

 . . . Now, a study suggests that two viruses that are related to Zika can cause similar birth defects.

West Nile and Powassan viruses caused fetal death in infected pregnant mice, the researchers say.

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CLICK HERE - NEJM - Zika Virus and Birth Defects — Reviewing the Evidence for Causality

 

 

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Seas to Rise About a Meter Even if Climate Goals Are Met - Study

           

FILE PHOTO: Uninhabitable apartments, in danger of collapsing into the Pacific Ocean, line Esplanade Ave. in Pacifica, California January 26, 2016. REUTERS/Noah Berger/File Photo

CLICK HERE - STUDY - Committed sea-level rise under the Paris Agreement and the legacy of delayed mitigation action

reuters.com - Alister Doyle - February 20, 2018

Sea levels will rise between 0.7 and 1.2 meters (27-47 inches) in the next two centuries even if governments end the fossil fuel era as promised under the Paris climate agreement, scientists said on Tuesday.

Early action to cut greenhouse gas emissions would limit the long-term rise, driven by a thaw of ice from Greenland to Antarctica that will re-draw global coastlines, a German-led team wrote in the journal Nature Communications . . .

 . . . By 2300, the report projected that sea levels would gain by 0.7-1.2 meters, even if almost 200 nations fully meet goals under the 2015 Paris Agreement, which include cutting greenhouse gas emissions to net zero in the second half of this century . . . 

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China Confirms First Ever Human Case of H7N4 Bird Flu

           

China has confirmed first ever human case of H7N4 bird flu Photograph: Kin Cheung/AP

CLICK HERE - The Government of Hong Kong Special Administrative Region - Press Release

A 68-year-old patient from Jiangsu province, who has since recovered, developed symptoms on Christmas Day and was admitted to hospital

theguardian.com - by Tom Phillips - February 15, 2018

A woman from eastern China has been confirmed as the first ever human case of H7N4 bird flu, according to Chinese authorities . . .

 . . . The 68-year-old patient from Jiangsu province, who has since recovered, developed symptoms on 25 December, was admitted to hospital for treatment on 1 January and was released on 22 January. 

“She had contact with live poultry before the onset of symptoms,” Hong Kong’s centre for health protection (CHP) said in an alert on Wednesday evening. “According to a report from the Chinese centre for disease control and prevention, upon analysis, the genes of the virus were determined to be of avian origin.”

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Risk of Extreme Weather Events Higher if Paris Agreement Goals Aren't Met

                                                

CLICK HERE - RESEARCH - STUDY - Unprecedented climate events: Historical changes, aspirational targets, and national commitments

sciencedaily.com - by Stanford University - Taylor Kubota - February 14, 2018

The individual commitments made by parties of the United Nations Paris Agreement are not enough to fulfill the agreement's overall goal of limiting global temperature rise to less than 2 degrees Celsius above pre-industrial levels. The difference between the U.N. goal and the actual country commitments is a mere 1 C, which may seem negligible. But a study from Stanford University, published Feb. 14 in Science Advances, finds that even that 1-degree difference could increase the likelihood of extreme weather.

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ALSO SEE RELATED ARTICLE HERE - Scientists Just Issued a Grim New Warning on Climate Change: 'We Are Not Prepared'

 

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Explosion, Fire at Power Plant Cause Blackout in Northern Puerto Rico

           

cbsnews.com - February 11, 2018

An explosion and fire at an electric substation threw much of northern Puerto Rico into darkness late Sunday in a setback for the U.S. territory's efforts to fully restore power more than five months after Hurricane Maria started the longest blackout in U.S. history. The island's Electric Power Authority said several municipalities were without power, including parts of the capital, San Juan, but they were optimistic it could be restored within a day as they worked to repair a substation that controls voltage.

The blast illustrated the challenges of restoring a power grid that was already crumbling before it was devastated by the Category 4 hurricane.

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ALSO SEE RELATED ARTICLE HERE - Explosion cuts power in Puerto Rico

 

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Satellite Observations Show Sea Levels Rising, and Climate Change Is Accelerating It

           

Changes in sea level observed between 1992 and 2014. Orange/red colors represent higher sea levels, while blue colors show where sea levels are lower.

CLICK HERE - STUDY - PNAS - Climate-change–driven accelerated sea-level rise detected in the altimeter era

cnn.com - by Brandon Miller - February 13, 2018

Sea level rise is happening now, and the rate at which it is rising is increasing every year, according to a study released Monday in the Proceedings of the National Academy of Sciences.

Researchers, led by University of Colorado-Boulder professor of aerospace engineering sciences Steve Nerem, used satellite data dating to 1993 to observe the levels of the world's oceans.

Using satellite data rather than tide-gauge data that is normally used to measure sea levels allows for more precise estimates of global sea level, since it provides measurements of the open ocean.

(CLICK HERE - READ COMPLETE ARTICLE)

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