Situation Report

Infection of developing human brain with the Zika virus (green) highlights susceptibility of radial glial cells during fetal development. Image by Elizabeth Di Lullo

CLICK HERE - STUDY - PNAS - Zika virus cell tropism in the developing human brain and inhibition by azithromycin

ucsf.edu - by Laura Kurtzman - November 29, 2016

Working in the lab, UC San Francisco researchers have identified fetal brain tissue cells that are targeted by the Zika virus and determined that azithromycin, a common antibiotic regarded as safe for use during pregnancy, can prevent the virus from infecting these cells . . .

 . . . In the new study, published online Nov. 29, 2016, in the Proceedings of the National Academy of Sciences (PNAS), the UCSF researchers determined that the Zika virus preferentially infects brain cells with an abundance of a protein called AXL, which spans the outer cell membrane of several cell types and serves as a gateway for the invading virus . . . 

CLICK HERE - Texas Department of State Health Services - Texas Announces Local Zika Virus Case in Rio Grande Valley

reuters.com - by Julie Steenhuysen - November 28, 2016

Texas health officials on Monday reported the state's first case of Zika likely spread by local mosquitoes, making Texas the second state within the continental United States to report local transmission of the virus that has been linked to birth defects.

The case involved a woman living in Cameron County near the Mexico border who is not pregnant, the Texas Department of State Health Services said.

Pregnancy is the biggest concern with Zika because the virus can cause severe, life-long birth defects, including microcephaly, in which a child is born with an abnormally small head, a sign its brain has stopped growing normally . . .

 . . . In adults, Zika infections have also been linked to a rare neurological syndrome known as Guillain-Barre, as well as other neurological disorders.

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Members of the Civil Defence rescue children after what activists said was an air strike by forces loyal to Syria's President Bashar al-Assad in al-Shaar neighbourhood of Aleppo, Syria June 2, 2014. REUTERS/Sultan Kitaz

reuters.com - by Alistair Scrutton - November 24, 2016

The inhabitants of besieged rebel-held eastern Aleppo have fewer than ten days to receive aid or face starvation and death from a lack of medical supplies, the head of the Syria Civil Defence, or "White Helmets", said on Thursday.

The volunteer group which works in opposition-held territory and has rescued thousands of people from buildings bombed in the civil war is also running out of basic equipment from trucks to diesel and gas masks . . . 

 . . . With freezing winter conditions setting in, about 275,000 people are trapped in eastern Aleppo, where the last U.N. food rations were distributed on Nov. 13.

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A mother and her 7-month-old daughter sit beneath a mosquito net at a hospital in Mogadishu, Somalia.  Roberto Schmidt /AFP/Getty Images

CLICK HERE - STUDY - Implications of insecticide resistance for malaria vector control (4 page .PDF file)

npr.org - by Jason Beaubien - November 22, 2016

. . . "there's growing evidence that mosquitoes are developing resistance to the insecticide used in the nets.

Now the World Health Organization has just completed a 5-year, 5-country study looking into whether nets might be becoming less effective."

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