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Relief Effort Underway for Flood-Ravaged Chennai in India

             

People walk through a flooded street in Chennai, India, Thursday, Dec. 3, 2015. The heaviest rainfall in more than 100 years has devastated swathes of the southern Indian state of Tamil Nadu, with thousands forced to leave their submerged homes, schools and offices. ( AP Photo) Associated Press

CLICK HERE - #ChennaiRains Resource Center

cnn.com - by Archith Seshadri - December 7, 2015

Chennai, a city of 4.6 million people on India's southeast coast, is reeling from some of the heaviest and deadliest rains in decades. . . .

"The value of Wi-Fi access cannot be underestimated," said Sharanya Manivanan of Chennai. "Phone lines were down for days, but those with Internet access were able to make things happen.”

Tech workers created a crowdsourcing site called www.chennairains.org so people can find sources of food and shelter using their smartphones or computers.

Drinking water is a megaproblem . . .

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Disease Specialists Identify Post-Ebola Threats

             

The West Africa Ebola outbreak has led experts to consider what diseases might spark the next major infectious disease crisis. Waldo Swiegers/Bloomberg via Getty Images

Scientists to assemble a rogues’ gallery of viruses likely to spark the next international public-health crisis

nature.com - by Erika Check Hayden - December 7, 2015 - doi:10.1038/nature.2015.18952

As West Africans try to bring the calamitous Ebola outbreak to an end, the World Health Organization (WHO) has called scientists and doctors to Geneva, Switzerland, on 8 and 9 December to discuss which infectious disease is likely spark the next pandemic. . . 

. . . Nature canvassed infectious-disease specialists to find out which pathogens they thought would trigger the next global crisis, and which treatments and vaccines might be readied to combat them.

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Vodafone Launches Mobile Cash Transfer System in Ghana Where 15M People Do Not Have a Bank Account

             

Moving money: The service, called M-Pesa, will be branded Vodafone Cash in the West African state

thisismoney.co.uk - by City & Finance Reporter for the Daily Mail - December 7, 2015

Vodafone has launched its mobile cash transfer system in Ghana where 15m people do not have a bank account.

The service, called M-Pesa, will be branded Vodafone Cash in the West African state. It allows mobile phone users to load money on to their phones, just as pay-as-you-go customers can top up their credit. 

They can send the funds anywhere in the country with a text message. Recipients can pick up the cash at shops that offer the service.

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Mathematical Modeling of the West Africa Ebola Epidemic

eLife 2015;10.7554/eLife.09186 - December 8, 2015
DOI: http://dx.doi.org/10.7554/eLife.09186

Abstract

As of November 2015, the Ebola virus disease (EVD) epidemic that began in West Africa in late 2013 is waning. The human toll includes more than 28,000 Ebola virus disease (EVD) cases and 11,000 deaths in Guinea, Liberia, and Sierra Leone, the most heavily-affected countries. We reviewed 66 mathematical modeling studies of the EVD epidemic published in the peer-reviewed literature to assess the key uncertainties models addressed, data used for modeling, public sharing of data and results, and model performance. Based on the review, we suggest steps to improve the use of modeling in future public health emergencies.

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Identification of NPC1 as the Target of U18666A, an Inhibitor of Lysosomal Cholesterol Export and Ebola Infection

eLife 2015;10.7554/eLife.12177 - DECEMBER 8, 2015
DOI: http://dx.doi.org/10.7554/eLife.12177

Abstract

Niemann-Pick C1 (NPC1) is a lysosomal membrane protein that exports cholesterol derived from receptor-mediated uptake of LDL, and it also mediates cellular entry of Ebola virus. Cholesterol export is inhibited by nanomolar concentrations of U18666A, a cationic sterol. To identify the target of U18666A, we synthesized U-X, a U18666A derivative with a benzophenone that permits ultraviolet-induced crosslinking. When added to CHO cells, U-X crosslinked to NPC1. Crosslinking was blocked by U18666A derivatives that block cholesterol export, but not derivatives lacking blocking activity. Crosslinking was prevented by point mutation in the sterol-sensing domain (SSD) of NPC1, but not by point mutation in the N-terminal domain (NTD). These data suggest that the SSD contains a U18666A-inhibitable site required for cholesterol export distinct from the cholesterol-binding site in the NTD. Inasmuch as inhibition of Ebola requires 100-fold higher concentrations of U18666A, the high affinity U16888A-binding site is likely not required for virus entry. 

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At Climate Talks, African Nations Pledge to Restore Forests

         

FILE - In this Sunday, March 21, 2010 file photo, shafts of sunlight filtering through the forest canopy strike smoke from fires burning outside family huts at an Mbuti pygmy hunting camp in the Okapi Wildlife Reserve outside the town of Epulu, Congo. Tree by tree, more than a dozen African governments pledged to restore the continent’s natural forests at the U.N. climate change talks in Paris on Sunday, Dec. 6, 2015. (Rebecca Blackwell,File/Associated Press)

CLICK HERE - World Resources Institute - African Countries Launch AFR100 to Restore 100 Million Hectares of Land

CLICK HERE - African Forest Landscape Restoration Initiative (AFR100)

CLICK HERE - Global Landscapes Forum

washingtonpost.com - by Lynsey Chutel - December 6, 2015

JOHANNESBURG — Tree by tree, more than a dozen African governments pledged to restore the continent’s natural forests at the United Nations climate talks on Sunday.

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Secretary-General Appoints David Nabarro of United Kingdom Special Adviser on 2030 Agenda for Sustainable Development

                                                                 

un.org - December 3, 2015

United Nations Secretary-General Ban Ki-moon today announced the appointment of David Nabarro of the United Kingdom as Special Adviser on the 2030 Agenda for Sustainable Development.  The Special Adviser will work with Member States and other relevant stakeholders to galvanize action on implementation of the Agenda, while also overseeing the Secretary-General’s special initiatives, for example, “Every Woman Every Child”.

Dr. Nabarro has more than 30 years experience in public health, nutrition and development work at the national, regional and global levels, and has held positions in non-governmental organizations, universities, national Governments and the United Nations system.

Since September 2014, he has served as Special Envoy of the Secretary-General on Ebola, providing strategic and policy direction for the international response.  From 2005 to 2014 he was Senior Coordinator for Avian and Pandemic Influenza.  From 2011 to 2015, he served as Coordinator of the Movement to Scale Up Nutrition, and since 2009 he has been the Special Representative of the Secretary-General for Food Security and Nutrition, a position he will continue to hold.

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WHO Urges Ukraine to Declare State of Emergency Amid Polio Outbreak

                                        

CLICK HERE - UNICEF - Ukraine

The Associated Press - December 1, 2015

KIEV, Ukraine - The World Health Organization is urging Ukraine's health ministry to declare a state of emergency due to a polio outbreak, a move meant to prompt more action from the government in Kyiv.

In September, Ukraine announced two polio cases -- the first in Europe since 2010.

The UN health agency recommended that Ukraine declare a state of emergency and "respond to the polio outbreak as quickly and effectively as possible," Dorit Nitzan, head of the WHO's office in Ukraine, told journalists.

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ALSO SEE SAME ARTICLE IN THE LINKS BELOW:

http://www.nytimes.com/aponline/2015/12/01/world/europe/ap-eu-ukraine-polio-.html?_r=0

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