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WHO mulls reforms to repair reputation after bungling Ebola

ASSOCIATED PRESS  by Marian Cheng                                                                       Jan. 25, 2015

GENEVA  — The World Health Organization is debating how to reform itself after botching the response to the Ebola outbreak, a sluggish performance that experts say cost thousands of lives.

On Sunday, WHO's executive board planned to discuss proposals that could radically transform the United Nations health agency in response to sharp criticism over its handling of the West Africa epidemic.

"The Ebola outbreak points to the need for urgent change," said Dr. Margaret Chan, WHO's director-general. She acknowledged that WHO was too slow to grasp the significance of the Ebola outbreak, which is estimated to have killed more than 8,600 people, mainly in Guinea, Liberia and Sierra Leone.

"The groundswell of dissatisfaction and lack of trust in WHO over Ebola has reached such a crescendo that unless there is fundamental reform, I think we might lose confidence in WHO for a generation," said Lawrence Gostin, director of the WHO Collaborating Center on Public Health Law and Human Rights at Georgetown University.

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Nurse who contracted Ebola released from hospital

THE GUARDIAN   by Lin Jenkins                                     Jan. 23, 2015

LONDON --The British nurse who almost died after contracting Ebola while volunteering in Sierra Leone has been discharged from hospital after making a full recovery.

Doctors had described her condition as “critical” during the three weeks she received treatment for the deadly virus and her family and friends were preparing for the worst. Cafferkey admited that then she had felt like “giving up”, but was now looking forward to returning to “normal life” and had no plans to go back to Africa.

The 39-year-old nurse was diagnosed with Ebola after returning to Glasgow last month and was admitted to the city’s Gartnavel hospital on December 29 before being transferred the next day to the Royal Free. She had been working with Save the Children at the Ebola treatment centre in Kerry Town before returning to the UK...

Save the Children has launched an investigation into how Cafferkey was infected, but admits it may never establish the exact circumstances.

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Sierra Leone eases blocks on travel, business as Ebola wanes

ASSOCIATED PRESS  by Clarence Roy-Macaulay                                                                  Jan. 23, 2015

FREETOWN, Sierra Leone (AP) -- With the Ebola outbreak weakening in West Africa, Sierra Leone eased restrictions on movement and commercial activity Friday even as the president warned that the fight against the deadly disease is not yet over.

The outbreak has sickened more than 21,000 people, nearly half of them in Sierra Leone. But the number of new infections is now falling in Sierra Leone, Guinea and Liberia, the three most affected countries.

President Ernest Bai Koroma announced in a national broadcast that, starting Friday, the country would lift all district quarantines and extend business hours on Saturdays. Koroma said that while people must remain vigilant, easing the restrictions would jump-start the economic recovery. In addition to its human toll, Ebola has hammered the economies of the three most affected West African nations...Sierra Leone plans to reopen schools in March...

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http://news.yahoo.com/sierra-leone-eases-blocks-travel-160805983.html;_ylt=AwrBEiI3ssNUX2IAGH3QtDMD

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Just five Ebola cases left in Liberia, government says

REUTERS                                                                                                  Jan. 23, 2015

MONROVIA-- Liberia, once the epicenter of West Africa's deadly Ebola epidemic, has just five remaining confirmed cases of the disease, a senior health official said on Friday, highlighting the country's success in halting new infections.

...a massive international response -- including the deployment of hundreds of U.S. troops to build treatment centers -- plus a public awareness campaign, contributed to a steep decline in infection rates.

Health workers take the temperature of a boy who came in contact with a woman who died of Ebola virus in the Paynesville neighborhood of Monrovia, Liberia, January 21, 2015.Credit: Reuters/James Giahyue

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Ebola Infections Dropping in West Africa, World Health Organization Says

NEW YORK TIMES by NICK CUMMING-BRUCE                                                                         Jan. 23, 2015

GENEVA — The number of people falling victim to the Ebola virus in West Africa has fallen to the lowest level in months, the World Health Organization said on Friday, but dwindling funds and a looming rainy season threaten to hamper efforts to control the disease.

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Flu & Drug Resistance Are Next Pandemic Threats After Ebola

REUTERS    By Ben Hirschler                                   Jan. 23, 2015

DAVOS, Switzerland, Jan 23 (Reuters) - The worst-ever Ebola epidemic is waning, but after ravaging three West African nations and spreading fear from Dallas to Madrid, it has hammered home the message that the world needs a better detective system for emerging diseases.

Risks posed by pandemic threats such as deadly strains of flu and drug-resistant superbugs have shot up the agenda of global security issues at this year's World Economic Forum in Davos as politicians and scientists grapple with the lessons from an Ebola outbreak that has killed more than 8,600 people.

One thing is certain: more epidemics are coming and dense urban living, coupled with modern travel, will accelerate future infectious disease outbreaks.
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http://www.huffingtonpost.com/2015/01/23/flu-drug-resistance_n_6531066.html

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As Ebola Outbreak Recedes, Global Health Care Leaders Focus On Prevention, Coordinated Action

THE INTERNATIONAL BUSINESS TIMES   by Amy Nordrum                                                                      Jan. 23, 2015

The recent Ebola outbreak, for which the number of new cases reported each week in the three most severely affected countries is finally beginning to fall, underscores the need to prepare for the next disease outbreak. Global health leaders are asking what it will take to prevent the next disease outbreak from spiraling out of control as the global population approaches 7.5 billion people and grows more connected.

 

     A research assistant works on a vaccine for Ebola at the Jenner Institute in Oxford, England. Eddie Keogh/Reuters

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WHO says cash crunch, rains could thwart Ebola efforts

REUTERS             by Stehane Nebehy                                                                                    Jan. 23, 2015

GENEVA --Halting the spread of Ebola in West Africa will depend on mobilising funds and aid workers before the rainy season hits in April-May, otherwise it could up to take a year, the World Health Organization (WHO) warned on Friday.

But the WHO is set to run out of cash in mid-February, a key period as it tries to halt the deadly disease, a senior WHO official said.

"It is a programme that can stop transmission if we have the money and the people, and we don't have either," Dr. Bruce Aylward, WHO assistant director-general in charge of the Ebola response, told a news briefing before a special session of WHO's Executive Board on Sunday.

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http://www.reuters.com/article/2015/01/23/us-health-ebola-who-idUSKBN0KW1NL20150123

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First GSK Ebola vaccine shipment due to arrive in Liberia

REUTERS by Kate Kelland                                     Jan. 23, 2015

LONDON-- The first batch of GlaxoSmithKline's experimental Ebola vaccine has been shipped to West Africa and is expected to arrive in Liberia later on Friday, the British drugmaker said.

The shipment, of an initial 300 vials of the vaccine, will be the first to arrive in one of the three main Ebola-affected African countries, GSK said in a statement.

It will be used in the first large-scale vaccine trials in coming weeks, in which healthcare workers helping to care for Ebola patients will be among the first to get it...

The vaccine, co-developed by the National Institutes of Health in the United States and Okairos, a biotechnology firm acquired by GSK in 2013, is currently being tested in five small phase I safety trials in Britain, the United States, Switzerland and Mali involving around 200 healthy volunteers in total.

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http://uk.reuters.com/article/2015/01/23/uk-health-ebola-gsk-idUKKBN0KW0DU20150123

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Fast Track on Drug for Ebola Has Faltered

NEW YORK TIMES by Andrew Pollack                               Jan. 23, 2015

As Ebola raged through West Africa last summer, an experimental drug was tried for the first time on two American aid workers in Liberia who were gravely ill with the virus. Both recovered, one of them rapidly.

 

Medicago, in North Carolina, is gearing up for possible production of the Ebola drug ZMapp using its plant-based technology. Credit Gerry Broome/Associated Press

Though it could not be said for sure that the drug, ZMapp, was responsible, patients and doctors began clamoring for it. But there was enough to treat only a handful of patients. Federal officials vowed to produce more.

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