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The mission of the Global Health Working Group is to explore and improve current and emerging states of health and human security worldwide.

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This Working Group is focused on exploring current and emerging states of health and human security worldwide.
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Aboubacar Conte admin Albert Gomez Allan Anthony Carrielaj
Chisina Kapungu ChrisAllen Corey Watts CPetry DeannaPolk Elhadj Drame
Gavin Macgregor... Hadiatou Balde hank_test jranck JSole Kathy Gilbeaux
Lisa Stelly Thomas loguest Maeryn Obley mdmcdonald MDMcDonald_me_com Mika Shimizu
mike kraft njchapman Norea Tiaji Salaam-Blyther tnovotny

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The Horror of Zika in Haiti

Claudy (Photo by Karen Bultje)

blogs.pjstar.com - by John Carroll, MD - July 6, 2016

A wonderful friend of ours, Karen Bultje, who is a missionary in Haiti, has been caring for a young man named Claudy in her home for several days. Claudy lives in the Kenscoff mountains above Port-au-Prince. He recently became ill with a high fever, rash, and severe pain. He also began having weakness in his legs which prevented him from walking. His mother and family carried him down the mountains and he went by motorcycle taxi and tap-taps to Karen’s home in Port.

Karen and her nursing staff took Claudy to a local hospital where he was examined but he was sent back to Karen’s home. They said there was nothing they could do for Claudy. The family is not able to pay for care in any local private hospital in Port and the public hospitals are on strike.

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'Super Bacteria' Discovered in Rio's Waters as Olympics Near

          

Super bacteria found on Rio beaches, Olympic venues

cnn.com - by Flora Charner - July 5, 2016

Rio de Janeiro (CNN)A group of Brazilian scientists has detected a drug-resistant bacteria growing off some of Rio de Janeiro's most stunning beaches, in research being published a month before the city hosts the 2016 Olympic Games.

According to lead researcher Renata Picao, the "super bacteria" entered the city's waterways when sewage coming from local hospitals got channeled into the bay.

"We have been looking for 'super bacteria' in coastal waters during a one-year period in five beaches," Picao told CNN during a visit to her lab. "We found that the threats occur in coastal waters in a variety of concentrations and that they are strongly associated with pollution."

The samples were collected between 2013 and 2014. The superbug found was carbapenem-resistant Enterobacteriaceae, or CRE.

Picao said there is no reason to believe the levels have changed because raw sewage continues to flow into many waterways.

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ALSO SEE RELATED ARTICLES WITHIN THE LINKS BELOW . . .

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World Bank Contributes to Improved Disease Surveillance and Health Systems in West Africa following Ebola Epidemic

                                                

worldbank.org

WASHINGTON, June 29, 2016—In Guinea, Sierra Leone and Senegal, more than 33.3 million people will benefit from stronger health systems and more effective disease surveillance systems through US$110 million in International Development Association (IDA) financing, approved yesterday by the World Bank Group’s Board of Executive Directors. This is the first in a series of investments planned under the Regional Disease Surveillance Systems Enhancement Program (REDISSE), which aims to address systemic weaknesses within the human and animal health sectors that hinder effective disease surveillance and response. The REDISSE program was developed with financial support from the Bill & Melinda Gates Foundation and technical support from the World Health Organization and the U.S. Centers for Disease Control and Prevention.

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Report of the Independent Panel on the U.S. Department of Health and Human Services (HHS) Ebola Response

                    

disasterlit.nlm.nih.gov - June 30, 2016

This 57-page report summarizes a request to capture critical lessons from the Ebola epidemic of 2014-2016 and review the Department of Health and Human Services (HHS)'s international and domestic responses. It summarizes an Independent Panel's assessment of HHS's challenges, and, where appropriate, challenges facing the broader U.S. government. It describes notable opportunities for improvement in leadership and organization, communication, management, and logistics, as well as in development and use of vaccines and treatments. It also presents recommendations for addressing future urgent public health threats.

CLICK HERE - ADDITIONAL INFORMATION AND ACCESS TO THE REPORT - Report of the Independent Panel on the U.S. Department of Health and Human Services (HHS) Ebola Response

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CLICK HERE - ADDITIONAL INFORMATION AND ACCESS TO THE REPORT - Report of the Review Committee on the Role of the International Health Regulations (2005) in the Ebola Outbreak and Response

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How Mosquito Spit Might Affect Zika Risk

           

The inoculation of viruses into mosquito bite sites is an important and common stage of virus infections. Inflammation helps the virus replicate and spread. on Pingen et al./Immunity 2016 / Immunity

CLICK HERE - STUDY - Immunity - Host Inflammatory Response to Mosquito Bites Enhances the Severity of Arbovirus Infection

CLICK HERE - STUDY - PLOS Pathogens - Mosquito Saliva Increases Endothelial Permeability in the Skin, Immune Cell Migration, and Dengue Pathogenesis during Antibody-Dependent Enhancement

nbcnews.com - by Maggie Fox - June 21, 2016

Mosquito saliva might be even more important for spreading infection than anyone thought.

Two studies published in the past week show that mosquito saliva lures immune cells to the site of a bite, and tricks them into spreading any viruses, such as Zika virus, throughout the body.

Tests in mice show that mosquito spit is such an important factor that it could sometimes turn a normally benign viral infection deadly.

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Ibuprofen 'Disables' Ebola Virus

SPL

CLICK HERE - RESEARCH - Nature - Toremifene interacts with and destabilizes the Ebola virus glycoprotein

bbc.com - by James Gallagher - June 30, 2016

The painkiller ibuprofen and the cancer drug toremifene can disable the Ebola virus, say researchers.

Scientists used the UK's national synchrotron facility - Diamond Light Source - to analyse the virus in incredible detail.

They revealed the two drugs could bind to the crucial part of Ebola that the virus needs to infect cells.

However, the team warns this is just a starting point and more effective drugs need to be researched.

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ADDITIONAL REFERENCES ARE PROVIDED BELOW:

Toremifene interacts with and destabilizes the Ebola virus glycoprotein
http://www.nature.com/nature/archive/subject.html?code=326

Toremifene interacts with and destabilizes the Ebola virus glycoprotein
http://www.nature.com/subjects/ebola-virus

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CDC - Clinical Alert to U.S. Healthcare Facilities - Global Emergence of Invasive Infections Caused by the Multidrug-Resistant Yeast Candida auris

submitted by Carrie La Jeunesse

cdc.gov - June 24, 2016

Summary: The Centers for Disease Control and Prevention (CDC) has received reports from international healthcare facilities that Candida auris, an emerging multidrug-resistant (MDR) yeast, is causing invasive healthcare-associated infections with high mortality. Some strains of C. auris have elevated minimum inhibitory concentrations (MICs) to the three major classes of antifungals, severely limiting treatment options. C. auris requires specialized methods for identification and could be misidentified as another yeast when relying on traditional biochemical methods. CDC is aware of one isolate of C. auris that was detected in the United States in 2013 as part of ongoing surveillance. Experience outside the United States suggests that C. auris has high potential to cause outbreaks in healthcare facilities. Given the occurrence of C. auris in nine countries on four continents since 2009, CDC is alerting U.S. healthcare facilities to be on the lookout for C. auris in patients.

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New Studies Show Just How Tricky the Zika Virus Is

           

A strain of Aedes aegypti mosquitos feed from a membrane of blood in a research lab insectary in the Hanson Biomedical Sciences Building at the University of Wisconsin-Madison on May 17, 2016.  Jeff Miller / University of Wisconsin-Madison

CLICK HERE - STUDY - A rhesus macaque model of Asian-lineage Zika virus infection

CLICK HERE - STUDY - Human antibody responses after dengue virus infection are highly cross-reactive to Zika virus

nbcnews.com - by Maggie Fox - June 28, 2016

A batch of new studies show the Zika virus is trickier than it appeared at first glance, lurking for months in pregnant females and interfering with the immune system's response.

The findings help explain why the virus seems so mild in some people, yet causes devastating birth defects. And while the data suggests it is not going to be so easy to fight the epidemic, at least two studies offer some hope for a good, protective vaccine.

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New Doubts on Zika as Cause of Microcephaly

sciencedaily.com - June 24, 2016

Brazil's microcephaly epidemic continues to pose a mystery -- if Zika is the culprit, why are there no similar epidemics in other countries also hit hard by the virus? In Brazil, the microcephaly rate soared with more than 1,500 confirmed cases. But in Colombia, a recent study of nearly 12,000 pregnant women infected with Zika found zero microcephaly cases. If Zika is to blame for microcephaly, where are the missing cases?

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CLICK HERE - A Possible Link Between Pyriproxyfen and Microcephaly

necsi.edu - Dan Evans, Fred Nijhout, Raphael Parens, Alfredo J. Morales, Yaneer Bar-Yam, A possible link between pyriproxyfen and microcephaly, New England Complex Systems Institute (2016).

Abstract

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Togo Prexy Draws Up Post-Ebola Program For ECOWAS

-President Sirleaf Discloses
By: 
Alaskai Moore Johnson, Observer Health Correspondent

President Ellen Johnson Sirleaf assuring ECOWAS Commission President Marcel Alain De Souza (2nd from right), she and her colleagues’ support to his Commission on Friday, June 17, 2016

 

President Ellen Johnson Sirleaf has disclosed that her Togolese colleague, President Faure Essozimna Gnassingbé, has been given the task of drawing up a post-Ebola plan for the ECOWAS region.

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