Global Health

Researchers have identified two FDA-approved drugs that may be effective against the Ebola virus. This could shorten the time for developing new treatments.

HEALTHLINE NEWS  by  Shawn Radcliffe                                                         June 3, 2015

With a fast-moving epidemic like Ebola, doctors need to make use of every tool at their disposal. This includes giving a second life to already-approved drugs....

One research team is hoping to ease the epidemic by shortening the lengthy drug development process.

Their approach? Sifting through hundreds of existing drugs and other compounds for ones that might work against the Ebola virus....

Additional screening narrowed the list down to two potential drug candidates: Bepridil, a calcium channel blocker used to treat heart disease, and sertraline, an antidepressant more commonly known as Zoloft.

Both drugs are already approved by the FDA, although not for use against the Ebola virus.

Read complete story.

http://www.healthline.com/health-news/zoloft-could-be-a-treatment-for-ebola-virus-060315#1

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GETTING AROUND  The chikungunya virus spreads via mosquitoes in tropical regions. Now it has found a way to hijack a second mosquito, posing a threat to people in Europe, North America and China.

sciencenews.org - by Nathan Seppa - June 2, 2015

A crippling virus has slipped its bonds in Africa and Asia and is invading whole new continents faster than people canlearn to pronounce its name. In one decade, chikungunya (chihk-uhn-GUHN-yuh) fever has gone from an obscure tropical ailment to an international threat, causing more than 3 million infections worldwide. The virus has established itself in Latin America and may now have the wherewithal to inflict its particular brand of misery in cooler climates.

(READ COMPLETE ARTICLE)

BUSINESS WIRE                                                                       June 3, 2015
CARLSBAD, Calif.--(BUSINESS WIRE)--A team of scientists that is part of an international, multi-organizational effort to curb further spread of deadly Ebola in Sierra Leone has released their first dataset of the virus’ genetic structure online.

The genetic analysis is now on virological.organd available for the global scientific community to monitor the pathogen’s evolution in real-time and conduct research that can lead to more effective strategies against further outbreaks.

The team of British scientists, funded by the Wellcome Trust, is using semi-conductor next-generation sequencing (NGS) technology to generate data in a lab facilitated by Public Health England and International Medical Corps.

UN NEWS CENTRE                                                                                June 2, 2015

To help mobilize needed resources “in the last mile of the response” against the Ebola outbreak and to start the affected West African countries on the path of early recovery, United Nations Secretary-General Ban Ki-moon today announced that he will convene an international conference next month.
In Sierra Leone, local health workers plan for the day ahead, as they continue their vigilance against Ebola. Photo: WHO/S. Aranda

“All of your investments, all of the sacrifices and lives lost, and all of the risks that the relief workers took would be squandered if the outbreak recurs,” Mr. Ban cautioned in his remarks to an informal plenary of the UN General Assembly on the Organization’s Ebola response efforts.