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The mission of the Global Health Working Group is to explore and improve current and emerging states of health and human security worldwide.

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This Working Group is focused on exploring current and emerging states of health and human security worldwide.
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Chisina Kapungu ChrisAllen Corey Watts CPetry DeannaPolk Elhadj Drame
Gavin Macgregor... Hadiatou Balde hank_test jranck JSole Kathy Gilbeaux
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Ebola Lying in Wait

NEW YORK TIMES by Pam Belluck and William J. Broad     April 20, 2015

A growing body of scientific clues — some ambiguous, others substantive — suggests that the Ebola virus may have lurked in the West African rain forest for years, perhaps decades, before igniting the deadly epidemic that swept the region in the past year, taking more than 10,000 lives.

Around 2004 at a government hospital in Kenema, Sierra Leone, a team of American scientists and West African medical personnel found what appeared to be Ebola antibodies in nearly 9 percent of blood samples. Credit Carl De Souza/Agence France-Presse — Getty Images

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Social Pathways for Ebola Virus Disease in Rural Sierra Leone, and Some Implications for Containment

PLOS     by Paul Richards and others                                                          April. 17,  2015                  
The current outbreak of Ebola Virus Disease in Upper West Africa is the largest ever recorded. Molecular evidence suggests spread has been almost exclusively through human-to-human contact.

 Social factors are thus clearly important to understand the epidemic and ways in which it might be stopped, but these factors have so far been little analyzed.

 The present paper focuses on Sierra Leone, and provides cross sectional data on the least understood part of the epidemic—the largely undocumented spread of Ebola in rural areas. Various forms of social networking in rural communities and their relevance for understanding pathways of transmission are described. Particular attention is paid to the relationship between marriage, funerals and land tenure.

 Funerals are known to be a high-risk factor for infection. It is suggested that more than a shift in awareness of risks will be needed to change local patterns of behavior, especially in regard to funerals, since these are central to the consolidation of community ties.

http://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0003567

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Sole Australian-run Ebola treatment centre to close

SYDNEY MORNING HERALD by Dan Harrison                                                                       April 20, 2015
The Australian-funded Ebola treatment centre in Sierra Leone will shut its doors at the end of the month, following a stabilisation of the outbreak in West Africa.                           Health care workers at the Kenema Government Hospital in Sierra Leone. Photo: AP

Australian Foreign Minister Julie Bishop announced on Monday that Australia's sole facility, at Hastings airfield, near Sierra Leone's capital Freetown, would close on April 30.

Ms Bishop said the decision followed a process led by the government of Sierra Leone to rationalise and consolidate Ebola treatment centres.

Read complete story.
http://www.smh.com.au/federal-politics/political-news/sole-australianrun-ebola-treatment-centre-to-close-20150420-1moysj.html

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WHO leadership admits failings over Ebola, promises reform

REUTERS   by Tom MIles                                                                     April 19, 2015

GENEVA--The World Health Organization has admitted serious failings in its handling of the Ebola crisis and pledged reforms to enable it to do better next time, its leadership said in a statement seen by Reuters on Sunday.

"We have learned lessons of humility. We have seen that old diseases in new contexts consistently spring new surprises," said the statement, attributed to the WHO Director-General Margaret Chan and the deputy director-general and regional directors.

"We have taken serious note of the criticisms of the Organization that, inter alia, the initial WHO response was slow and insufficient, we were not aggressive in alerting the world ... we did not work effectively in coordination with other partners, there were shortcomings in risk communications and there was confusion of roles and responsibilities...," it said.

The statement listed eight lessons learned, including areas where the WHO's response to Ebola could have been better, such as information sharing and communication....

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Signs Ebola Spreads in Sex Prompt a C.D.C. Warning

NEW YORK TIMES  by SHeri Fink                                                                                  April 20, 2015
The Centers for Disease Control and Prevention revised its guidelines on Ebola transmission on Sunday night, urging survivors to abstain from all forms of sex or use condomsevery time “until more information becomes available,” rather than three months as previously recommended.

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Pesticides likely behind 'mysterious killer disease' in Nigeria

Deutsche Welle                                                                            April 19, 2015

 Eighteen people died under mysterious circumstances in southwest Nigeria this week, sparking fears of a new infectious disease outbreak. Weed killer was the likely cause, the World Health Organization has now said.

When over a dozen men in the village of Ode Irele in southwestern Ondo state who complained of similar symptoms all died within a day, alarm bells began to ring. However, according to the World Health Organization (WHO), there is no reason to suspect any outbreak of infectious disease, such as Ebola, which has claimed over 10,000 lives in Sierra Leone, Guinea and Liberia.

The "current hypothesis is herbicides," WHO spokesman Gregory Hartl said on Sunday, adding: "Tests done so far are negative for viral and bacterial infection."

The victims began showing symptoms between April 13 and 15, including blurred vision and loss of consciousness, and Ondo spokesman Kayode Akinmade said it was due to a "mysterious killer disease."

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Rebuilding after Ebola will require the world’s help

WASHINGTON POST EDITORIAL                             Aug. 18, 2015

THE RAVAGING of populations in Liberia, Sierra Leone and Guinea by the Ebola virus over the past year has been devastating. The virus killed 10,702 people and left behind vast economic and emotional tolls. The rest of the world responded slowly to the outbreak but eventually rallied. Now it is time to do the same with the aftermath and extend a hand for rebuilding...

The outbreak has receded, but weak local health-care systems proved inadequate when the virus began to spread last year, and improvements are vital in all three countries, especially a much-strengthened system of surveillance to spot any resurgence. Trained health-care workers are in short supply. A small but important step was taken recently in the announcement that the Centers for Disease Control and Prevention will help set up an African CDC that could keep the continent one step ahead of another scourge. But the rest of the world also has a stake in making sure that the region builds a better firewall against infectious disease....

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Paper and Phones Could Soon Diagnose Ebola and HIV for $1

NEWSWEEK  by Conner Gaffey                               April 16, 2015
Diseases such as HIV and Ebola are on the verge of being diagnosed almost instantly using paper-based technology costing less than $1.

                                       Diseases may soon be tested for via paper and smartphones Getty

The devices, known as biosensing platforms, are made from cheap materials including plastic film and cellulose paper. Results are captured using a smartphone camera and sent back to hospitals or clinics for immediate diagnosis.

Current HIV diagnosis can cost up $48 (45) for a negative test and $64 (60) for a positive test. Checks for Ebola cost some $100 (95), take up to six hours to produce a result and require sophisticated diagnostic equipment, the type of which is often unavailable in western Africa where the disease is especially prevalent.

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CDC announces smartphone coaching app for Ebola workers

CGN                                                    April 17, 2015

(Scroll down for underlying press release.)

The Centers for Disease Control and Prevention announced a free smartphone application that provides intuitive coaching on CDC's guidelines for proper use of personal protective equipment (PPE) to prevent transmission of Ebola.

Powered by 22otters, a mobile patient engagement platform, CDC's PPE app is an animated, speech-enabled, step-by-step mobile coaching tool to help healthcare workers access easy-to-follow directions for putting on and removing PPE and respirators in accordance with CDC guidelines to prevent transmission of Ebola. Following the initial Ebola app release, 22otters will release a variant of the app allowing training progress tracking and content modules customized for providers.

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Evaluating Clinical Trial Designs for Investigational Treatments of Ebola Virus Disease

PLOS MEDICINE   by Ben Cooper and others                                                             April 14, 2015
Experimental treatments for Ebola virus disease might reduce EVD mortality. There is uncertainty about the ability of different clinical trial designs to identify effective treatments, and about the feasibility of implementing individually randomised controlled trials during an Ebola epidemic

A treatment evaluation programme for use in EVD was devised using a multi-stage approach (MSA) with two or three stages, including both non-randomised and randomised elements. The probabilities of rightly or wrongly recommending the experimental treatment, the required sample size, and the consequences for epidemic outcomes over 100 d under two epidemic scenarios were compared for the MSA, a sequential randomised controlled trial (SRCT) with up to 20 interim analyses, and, as a reference case, a conventional randomised controlled trial (RCT) without interim analyses.

Read complete study.

http://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1001815

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