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The mission of the Global Health Working Group is to explore and improve current and emerging states of health and human security worldwide.

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This Working Group is focused on exploring current and emerging states of health and human security worldwide.
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Aboubacar Conte admin Albert Gomez Allan Anthony Carrielaj
Chisina Kapungu ChrisAllen Corey Watts CPetry DeannaPolk Elhadj Drame
Gavin Macgregor... Hadiatou Balde hank_test jranck JSole Kathy Gilbeaux
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mike kraft njchapman Norea Tiaji Salaam-Blyther tnovotny

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As Ebola Pingpongs In Liberia, Cases Disappear Into The Jungle

NATIONAL PUBLIC RADIO   By Kelly Mcevers                                                  Nov. 25, 2014
There's a new phase of Ebola in Liberia. Epidemiologists call it pingponging.

A rural health clinic about five hours outside Monrovia, Liberia. The clinic has a few rooms and no electricity.Kelly       McEvers/NPR

Back in March, the disease was found in the rural areas. Then as people came to the capital to seek care, it started growing exponentially there. Now, some sick people are going back to their villages, and the disease has pingponged to the rural areas again.

Read complete story and hear broadcast

http://www.npr.org/blogs/goatsandsoda/2014/11/25/366381386/as-ebola-ping-pongs-in-liberia-cases-disappear-into-the-jungle

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Saving lives without new drugs

SCIENCE        By Jon Cohen                                                                                         Nov. 21, 2014

...Just a handful of basic interventions to fight the killer effects of Ebola, including dehydration and secondary infections, could dramatically lower the CFR there, says Michael Callahan, an infectious disease specialist at Massachusetts General Hospital in Boston..

With so much room for improvement in supportive care, the current international focus on drugs is “misguided,” says Callahan, who has recently worked in Monrovia and provided care in four previous Ebola outbreaks. “While we wait for months for forthcoming experimental therapies, many lives can be saved, certainly hundreds and possibly thousands, using inexpensive and simple therapies,” he says.

Callahan is helping an international team develop guidelines dubbed Maximum Use of Supportive Therapy (MUST), aimed at keeping more patients alive. It includes intravenous (IV) drips to replace massive fluid loss from diarrhea and vomiting, a risk factor for shock; balancing of electrolytes such as calcium or potassium, which prevents kidney and heart failure; nasogastric tubes for feeding; and testing and treatment of secondary infections such as malaria. Introducing MUST will also make it easier to study new treatments, Callahan says...

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The Race for an Ebola Vaccine

Description of efforts by the big drug companies to develop an Ebloa vaccine
THE NEW YORKER    By Vauhine Vara                        Nov. 25, 2014

"...why this race to create an Ebola vaccine among Merck, GlaxoSmithKline, and Johnson & Johnson—three of the world’s biggest drug manufacturers? For years, pharmaceutical companies didn’t invest much in vaccines, partly because they were so costly and complicated to produce: they’re often made out of live bacteria, which are notoriously difficult to work with. But, over the past several years, companies have realized that the difficulties of making vaccines could be an asset, because they can make it more difficult for generic-drug companies to create copycat versions than for prescription drugs. The vaccine market has also been growing more quickly than the prescription-drug market. The World Health Organization estimates, based on various sources, that global vaccine sales rose from five billion dollars in 2000 to twenty-four billion dollars last year...."

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http://www.newyorker.com/business/currency/race-ebola-vaccine

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Projected Impact of Vaccination Timing and Dose Availability on the Course of the 2014 West African Ebola Epidemic

PLOS CURRENT OUTBREAKS                                                                              Nov. 21, 2014
By David Fisman and Ashleigh Tuite, Dalla Lana School of Public Health, University of Toronto

As removal of population-level susceptibility through vaccination could be a highly impactful control measure for this epidemic, we sought to estimate the number of vaccine doses and timing of vaccine administration required to reduce the epidemic size. Our base model was fit using the IDEA approach, a single equation model that has been successful to date in describing Ebola growth. We projected the future course of the Ebola epidemic using this model. Vaccination was assumed to reduce the effective reproductive number. We evaluated the potential impact of vaccination on epidemic trajectory under different assumptions around timing of vaccine availability.

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Here’s How the Ebola Vaccine Trial Is Doing

TIME MAGAZINE By Alexandra Sifferlin                          Nov. 25, 2014
 By  Alexandra Sifferlin                       

Scientists are scurrying to get their Ebola vaccines through the necessary safety trials before they can be used widely. That includes the University of Maryland School of Medicine, which recently kicked off the latest step in their research: figuring out the appropriate dosing for the vaccine that’s both effective and safe.

The University of Maryland is one of a handful of institutions involved in the testing of an experimental but promising vaccine developed by the National Institutes of Health’s Vaccine Research Center (VRC) and GlaxoSmithKline (GSK). The hope is that the vaccine will pass through early trials needed by end of December so that the World Health Organization (WHO) and a panel of outside experts can decide whether to move on to a large efficacy trial, which would mean vaccinating a lot of people in West Africa to see how well it works.

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Ebola In Mali: Eighth Person Tests Positive In Mali, Which Is Monitoring 271 People For Symptoms

INTERNATIONAL BUSINESS TIMES              By Sneha Shankar                                                 Nov.25, 2014

Officials in Mali confirmed an eighth case of the Ebola virus and said that it is monitoring 271 people suspected to have been infected by the virus. Mali is the sixth country to be dealing with the deadliest outbreak of the Ebola virus, which has so far killed over 5,400 people.

The government of Mali said that the latest case of Ebola closely follows another case, which was confirmed on Saturday, and both patients have been kept under isolation in an Ebola treatment center in the country, Reuters reported. All of the six previous cases, who tested positive for Ebola in the country, have died.

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U.S. Buys Up Ebola Gear, Leaving Little for Africa

Manufacturers Strain to Meet Demand Amid Rising Anxiety

WALL STREET JOURNAL                                                                                                       Nov. 25, 2014
 By Drew Hinshaw in Accra, Ghana, and Jacob Bunge in Chicago

Protective suits were running low in Sierra Leone this month, when a Christian charity decided to ship some over. The charity turned to American medical-wear suppliers, which came back with bad news: The suits needed to treat Ebola are running low in America, too.

A worker wearing Personal Protective Equipment has his name written on his suit before leaving an Ebola treatment center in Guinea last week. Agence France-Presse/Getty Images

“There’s been some sleepless nights,” said Jennifer Mounsey, director of corporate engagement for World Vision, the Christian humanitarian group based in Monrovia, Calif. “We’re all sweating bullets.”

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Ebola outbreak: Sierra Leone workers dump bodies in Kenema

BBC                                                                                                    Nov. 25, 2014  

Burial workers in the Sierra Leonean city of Kenema have dumped bodies in public in protest at non-payment of allowances for handling Ebola victims.

The workers, who went on strike over the issue, left 15 bodies abandoned at the city's main hospital.

             Burial workers are especially at risk of becoming infected

One of the bodies was reportedly left by the hospital manager's office and two others by the hospital entrance.

A BBC reporter in Sierra Leone says the striking workers have now been sacked. The hospital has not commented.

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http://www.bbc.com/news/world-africa-30191938

 

 

 

 

 

 

 

 

 

 

 

                                                                                         

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People are treating Africa like a country because of Ebola

From Monrovia to Guangdong, Africans can't escape the stigma. (Reuters/Alex Lee)Benno Muchler - November 25, 2014 - qz.com

Ebola was one of the biggest news stories this year. What did we learn from it? Not much. Panic and fear replaced rational thinking. And there was another pernicious behavior we didn’t change.

Ebola would have been a chance to start differentiating Africa. Yet, we’re doing quite the opposite. We continue to look at Africa as one country. We act as if the whole continent is contaminated. And most sadly, outside Africa we stigmatize Africans, no matter which part of the continent they’re from, because of Ebola.

Read the whole article here:

http://qz.com/301707/people-are-treating-africa-like-a-country-because-of-ebola/

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Ebola Is Changing Course In Liberia. Will The U.S. Military Adapt?

A helicopter's eye view of a new ETU, funded by USAID and built by Save the Children.November 25, 2014 - by Kelly McEvers - npr.org

The Ebola outbreak started in rural areas, but by June it had reached Liberia's capital, Monrovia.

By August, the number of people contracting the Ebola virus in the country was doubling every week. The Liberian government and aid workers begged for help.

Enter the U.S. military, who along with other U.S. agencies had a clear plan in mid-September to build more Ebola treatment units, or ETUs. At least one would be built in the major town of each of Liberia's 15 counties. That way, sick patients in those counties wouldn't bring more Ebola to the capital.

But it's taken a long time to build these ETUs; most won't be done until the end of the year. And now the spread of Ebola changing — clusters are popping up in remote rural areas. So building a huge treatment center in each county's main town may no longer make sense.

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