Africa Resilience Initiative

GENOMEWEB                                                                                                                        Dec. 22, 2014
NEW YORK -- Tekmira Pharmaceuticals announced today that it has signed a deal that will support the clinical testing of its experimental Ebola therapy designed against the strain of the virus behind the outbreak in West Africa.

Tekmira has long been developing an siRNA-based Ebola drug called TKM-Ebola, but a Phase I study of that agent was suspended by US regulators until the company could provide additional safety data. Earlier this year, Tekmira management indicated that that trial might not restart as early as anticipated since the firm had begun focusing on a version specifically for the Guinea strain of the Ebola virus, which is driving the ongoing outbreak.

Tekmira said it has now inked a manufacturing and clinical trial agreement with the University of Oxford to provide the new drug, called TKM-Ebola-Guinea, for clinical trials in West Africa. The university is the representative of the International Severe Acute Respiratory and Emerging Infection Consortium, which will be testing TKM-Ebola-Guinea in infected individuals with funding from the Wellcome Trust.

MILITARY TIMES By Andrew Tilghman                                                                                Dec. 19, 2014
Thousands of troops deployed to West Africa to help contain the Ebola virus will have to wait a few more weeks to find out whether the policy of 21-day quarantines after their redeployment will continue, military officials said.

The Pentagon has granted an extension on the deadline for reviewing the controversial rule requiring a 21-day, post-deployment quarantine. The review will now be completed by Jan. 30, 2015.

When Defense Secretary Chuck Hagel announced the quarantine on Oct. 29, he ordered military officials to conduct a review within 45 days to determine whether it was effective and necessary.

That review was due on Dec. 12, but Hagel granted a seven-week extension following a request from the chairman of the Joint Chiefs, Army Gen. Martin Dempsey.

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REUTERS   by    Emma Farge                                                                                                 Dec. 21, 2014       
KOIDU, Sierra Leone -- The rapid response team has arrived and the chaos is easing, but medics in a remote Sierra Leonean district are struggling to control a local Ebola outbreak when it's too late to nip it in the bud.

Health workers rest outside a quarantine zone at a Red Cross facility in the town of Koidu, Kono district in Eastern Sierra Leone December 19, 2014. Credit: Reuters/Baz Ratner

A deployment of medical workers and equipment to Kono District has been the fastest so far in Sierra Leone, a country with nearly half the total Ebola cases,- under a strategy of tackling epidemic hotspots before they get too big.

But officials say responses need to be yet faster to fight the fever that has killed more than 7,000 people across West Africa.

WASHINGTON POST OP-ED by Claudena Skran                                                                      Dec. 20, 2014

No evacuation plane to the United States or Europe awaited Dr. Thomas Rogers in early December when he fell ill with the Ebola virus in Sierra Leone.

Instead, the highly trained physicianstruggled to be admitted to one of the few Ebola treatment centers in the West African country. After finally securing a bed, Rogers died on Dec. 5 , sharing the tragic course of the Ebola epidemic with his countrymen.