Africa Resilience Initiative

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Sat, 2009-03-21 11:57 — mdmcdonald

The mission of this working group is to articulate and shape issues of resilience and sustainability on the continent of Africa as they may be implemented as reforms of current policies, as well as contemplate and make recommendations for more extensive critiques and proposals for national, provincial, and local systems transformation, as may be necessary or desirable beyond the scope of traditional reforms being undertaken by the current African national governments and local government proposals in Africa.

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This working group is focused on developing an Africa Resilience Initiative to ensure resilience and sustainability for all Africans.

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Aboubacar Conte	admin	Anthony	bnorton	Carrielaj	Chisina Kapungu
ChrisAllen	craig.sevcik	Dr Ojia Adamolekun	efrost	Elhadj Drame	Grace Kim
Hadiatou Balde	jranck	Kathy Gilbeaux	mdmcdonald	MDMcDonald_me_com	mike kraft
njchapman	Norea	SmShako	TacarraB	Tjivekumba Kandjii

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Ebola crisis points to wider global threat on a par with al-Qaida, warns UK medic

Fri, 2015-03-27 21:35 — mike kraft

THE GUARDIAN by Lisa O'Carroll March 27, 2015

Ebola should be seen as an early wake-up call to world leaders of the potential for an international health disaster in the same way that the 1998 US embassy bombings highlighted the possibility of further attacks by al-Qaida, a leading British medic in Sierra Leone has warned.

Dr Oliver Johnson has called for “a big political shakeup” at the World Health Organisation and says Britain’s Department for International Development must decide whether to “nationalise” aid and deploy the army the next time a humanitarian emergency hits.

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The tail of the epidemic and the challenge of tracing the very last Ebola case

Fri, 2015-03-27 20:53 — mike kraft

EUROSURVEILLANCE by K. Kaasik-Aaslav and D. Coulombier March 26, 2015

Upon entering what seems to be the tail of the epidemic and, as in any such moment, the ‘Ebola endgame’ strategy requires adaptation to the heterogeneity of the epidemiological situation. The tools for EVD control need to be fine-tuned and the commitment from the teams supporting local authorities in affected countries needs to be sustained.

While the pressure on clinical and laboratory expertise gradually decreases, the demand shifts towards field epidemiologists to assist local public health experts and support community workers to engage in active surveillance and to monitor remaining transmission chains in affected communities.

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Liberia's sole remaining known Ebola patient dies

Fri, 2015-03-27 20:23 — mike kraft

REUTERS March 27, 2015

MONROVIA - A woman who was Liberia's sole remaining known Ebola patient died on Friday at a treatment center in the capital, said Francis Ketteh, acting head of the country's Ebola response team.

The case was Liberia's first in weeks and it set back efforts to halt a virus that has killed more than 10,000 people in Liberia, Guinea and Sierra Leone. Authorities say the woman may have contracted Ebola through sex with a survivor.

"We have been able to trace the people she came in contact with," Ketteh said. "We call on everyone to follow the Ebola preventative measures."

Read complete story.

https://uk.news.yahoo.com/liberias-sole-remaining-known-ebola-patient-dies-223054495.html#Vsr2JM7

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Laboratory support during and after the Ebola virus endgame: towards a sustained laboratory infrastructure

Fri, 2015-03-27 15:05 — mike kraft

EUROSURVEILLANCE by I. Goodfellow, C. Reusken, and M. Koopmans

March 26, 2015

The Ebola virus epidemic in West Africa is on the brink of entering a second phase in which the (inter)national efforts to slow down virus transmission will be engaged to end the epidemic. The response community must consider the longevity of their current laboratory support, as it is essential that diagnostic capacity in the affected countries be supported beyond the end of the epidemic.

The emergency laboratory response should be used to support building structural diagnostic and outbreak surveillance capacity.

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Scientists argue over access to remaining Ebola hotspots

Fri, 2015-03-27 14:24 — mike kraft

SCIENCE by Kai Kupferschmidt March 26, 2015

The slowdown in the West African Ebola epidemic is welcome news and reason to be hopeful—but it’s also creating a new problem. With fewer new cases occurring, it is becoming more and more difficult to test vaccines and drugs. As a result, conflicts are looming over who can test Ebola drugs and vaccines in Guinea and Sierra Leone.

An Ebola treatment unit in Guinea.Samuel Hanryon/MSF

In Guinea, a large consortium that includes Doctors Without Borders (MSF) and the World Health Organization (WHO) vaccinated the first volunteers at risk of Ebola on Monday in a big trial of a vaccine produced by Merck and NewLink Genetics. But the team feels threatened because researchers at the U.S. National Institutes of Health (NIH) are looking to move another vaccine study from Liberia, where the epidemic has come to a virtual standstill, to Guinea.

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Ebola whole virus vaccine shown effective, safe in primates

Fri, 2015-03-27 11:01 — mike kraft

SCIENCE DAILY March 26, 2015

(Scroll down for complete paper.)
An Ebola whole virus vaccine, constructed using a novel experimental platform, has been shown to effectively protect monkeys exposed to the often fatal virus.

The vaccine, described today (March 26, 2015) in the journal Science, was developed by a group led by Yoshihiro Kawaoka, a University of Wisconsin-Madison expert on avian influenza, Ebola and other viruses of medical importance. It differs from other Ebola vaccines because as an inactivated whole virus vaccine, it primes the host immune system with the full complement of Ebola viral proteins and genes, potentially conferring greater protection.

"In terms of efficacy, this affords excellent protection," explains Kawaoka, a professor of pathobiological sciences in the UW-Madison School of Veterinary Medicine and who also holds a faculty appointment at the University of Tokyo. "It is also a very safe vaccine."

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Two experimental Ebola vaccines pass safety test in African trial

Fri, 2015-03-27 10:03 — mike kraft

REUTERS by Sharon Begley March 26, 2015

NEW YORK - Two experimental Ebola vaccines, one from GlaxoSmithKline PLC and the other from biotech start-up NewLink Genetics Corp, "appear to be safe" part way through a clinical trial being conducted in Liberia, the U.S. National Institutes of Health (NIH) said on Thursday.

The two vaccines, each given in a single injection, are being tested for safety and efficacy on more than 600 people in Liberia in a mid-stage clinical trial sponsored by the National Institute of Allergy and Infectious Diseases, a branch of NIH.

The Ebola epidemic that began in West Africa one year ago has killed more than 10,200 people, but a decline in new cases in the most affected countries, Liberia, Guinea and Sierra Leone, has led to hopes that it may be ending.

Based on the encouraging safety results, the study may now advance to the next phase of efficacy testing, in which additional volunteers are injected with the GSK vaccine, the NewLink vaccine, or a dummy shot and assessed to see whether their immune system responds by producing anti-Ebola antibodies.

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Ebola virus not mutating as quickly as thought

Thu, 2015-03-26 16:17 — mike kraft

SCIENCE NEWS by Ashley Yaeger March 26, 2015

(Scroll down for full study.)

The virus causing the current Ebola epidemic in West Africa is not evolving as quickly as some scientists had suggested.

REGULAR RATE A genetic analysis suggests that the Ebola virus, shown here in orange, is not evolving as fast as expected.

In a paper last August, researchers reported that the virus (Zaire ebolavirus) was altering its genes almost twice as fast as it had during previous Ebola outbreaks in Central Africa (SN: 9/20/14, p. 7). However, a new genetic analysis shows that the virus is mutating at roughly the same rate as in past outbreaks, researchers report online March 26 in Science. The finding suggests the virus has not become more virulent or transmissible during the West Africa outbreak.

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Ebola upsurge could undo progress in blink of an eye, warns expert

Thu, 2015-03-26 10:32 — mike kraft

THE GUARDIAN by Sam Jones March 26, 2015

Despite the massive push to bring the number of new Ebola cases down to zero as quickly as possible, there will inevitably be “flare-ups” that could reverse the overall downward trend and prove difficult to contain, the UN’s response co-ordinator has warned.

Dr David Nabarro, the UN’s special envoy for Ebola, said the huge medical, administrative and logistical operation to fight the disease could still be set back by individuals ignoring official advice.

“There will be flare-ups, there will be disappointments; there will be people who evade quarantine – because nobody likes being told to stay put – there will be people who choose not to declare that they’ve got a relative ill, there will be people who get ill and just misdiagnose themselves,” he said....

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How Did Ebola Volunteers Know Where To Go In Liberia? Crowdsourcing!

Thu, 2015-03-26 09:04 — mike kraft

NATIONAL PUBLIC RADIO by Poncie Rutsch March 25, 2015
From more than 900 miles away, Kpetermeni Siakor helped get volunteers to the right neighborhoods in his native Liberia during the height of the Ebola epidemic.

Kpetermeni Siakor (left), a Liberian who is studying in Ghana, used crowdsourcing software to help out during the Ebola epidemic. Courtesy of Ashesi University College

He did it with Ushahidi, crowdsourcing software that was developed in Kenya in 2008, when the country experienced a wave of post-election violence. The word Ushahidi means testimony in Swahili.

"The government had shut down internet connections and radio stations, so Ushahidi was born out of the need to let people know what is happening," says Siakor, 26. He's a computer science student at Ashesi University College in Accra, Ghana, and receives financial support from the MasterCard Foundation Scholars Program.

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