FDA approves Corgenix's Ebola test for emergency use

REUTERS                                                           Feb. 26, 2015

Diagnostics company Corgenix Medical Corp said on Thursday U.S. health regulators had approved its rapid Ebola test for emergency use, in response to the world's worst outbreak of the virus that killed more than 10,000 so far.

The company's ReEBOV Antigen Rapid Test, which involves putting a drop of blood on a paper strip and waiting for at least 15 minutes for a reaction, was cleared by the World Health Organization last week.

The test is less accurate than the standard test, which has a turnaround time of 12-24 hours, but is easy to perform and does not require electricity. It is able to correctly identify about 92 percent of Ebola-infected patients and 85 percent of those not infected with the virus, the WHO said.

The WHO is still assessing four or five other rapid test candidates.

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http://www.reuters.com/article/2015/02/26/us-health-ebola-testing-idUSKBN0LU1OO20150226

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It Kills Germs For Up To 6 Hours. Can It Wipe Out Ebola?

NATIONAL PUBLIC RADIO  by Emily Sohn                                                              Feb. 27, 2015

Clean hands go a long way toward preventing the spread of many illnesses, including Ebola. But finding the right hand-wash to impede deadly germs is tricky.

           A health worker in Liberia washes up after leaving a clinic's Ebola isolation area. Tommy Trenchard for NPR

A squirt of alcohol-based sanitizer like Purell kills or denatures many microbes on contact. In the case of bacteria, essentially poking holes in their cell membranes, causing them to shrivel up like water balloons. For viruses, the mechanism is not well-understood. But alcohol evaporates after 15 seconds, allowing for rapid recontamination...

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Rapid Response to Ebola Outbreaks in Remote Areas — Liberia, July–November 2014 Weekly

Morbidity and Mortality Weekly Report (MMWR)

 CDC                                                                        Feb. 27, 2015

Outbreaks in remote areas posed a significant challenge to CHTs to mount an effective investigation and rapid response because of limited resources, personnel, and means to reach remote areas.

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http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6407a7.htm?s_cid=mm6407a7_x

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The world should learn from the Ebola crisis to combat MERS in Saudi Arabia

EDITORIAL, THE WASHINGTON POST                                                                      Feb. 27, 2015

A DISEASE outbreak has a source and a pathway for transmission, but both can be exceedingly difficult to discover. Middle East respiratory syndrome, or MERS, is surging anew in Saudi Arabia and raising familiar questions: Where is this coronavirus coming from and how is it spreading?

 

A man wearing a mask looks on as he stands in front of camels at a camel market in the village of al-Thamama near Riyadh May 11, 2014. Saudi Arabia said people handling camels should wear masks and gloves to prevent spreading Middle East Respiratory Syndrome (MERS), (Faisal Al Nasser/Reuters)

There is growing evidence that the natural reservoir of MERS, which first appeared in 2012, is dromedary camels, and last year’s peak in the spring seemed to coincide with the weaning period of camel calves. A new seasonal oscillation may be starting now. But there are worrisome and unexplained gaps in recent case reports.

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Ebola: Sierra Leone village in lockdown after 31 new cases recorded

THE GUARDIAN by Lisa O'Carroll                         Feb. 27, 2015

Efforts to beat Ebola in Sierra Leone have been dealt a setback after 31 new cases were recorded in one village.

                            Red Cross healthcare workers. 

The community of 500 just outside the town of Makeni has now been put in lockdown by the army amid fears that more could be infected.

The World Health Organisation said cases have been linked to one man who escaped a quarantine in Freetown to go home to his village to get treatment from a traditional faith healer.

The quarantine area is a fishing community, yards from the hotel where many of humanitarian agencies have stayed.

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http://www.theguardian.com/world/2015/feb/27/ebola-sierra-leone-village-lockdown-31-new-cases

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Ebola halts HIV progress in Sierra Leone, says UN

Thomson Reuters Foundation by Misha Hussain                                                        Feb.27, 2015

 DAKAR -- The West African Ebola outbreak has halted progress in tackling HIV in Sierra Leone, shutting health clinics and scaring patients from being tested or seeking treatment, the United Nations has said.

In an internal document seen by the Thomson Reuters Foundation, the United Nations Development Programme (UNDP) raised concerns that HIV prevalence and drug resistance in the country could increase as a result.

"Hospitals have closed down because they have been overrun by Ebola patients and non-Ebola patients are too afraid to go to them for fear of catching the virus," said Hakan Bjorkman, who manages UNDP's AIDS programme.

"HIV prevention activities in schools and awareness raising for the general population has been suspended due to the restriction of movement, the closure of all education institutions and the overall ban on public gathering."

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Decision on Ebola mass vaccination in August at earliest: WHO

REUTERS by Stephanie Nebehay                                                             Feb. 27, 2015

GENEVA -- An independent advisory body will decide in August at the earliest on whether to recommend widespread introduction of an Ebola vaccine, depending on results of clinical trials and the epidemic's course, the World Health Organization said on Friday.

All three worst-hit countries in West Africa - Guinea, Liberia and Sierra Leone - aim to conduct phase III final-stage clinical trials of experimental vaccines.

Liberia is already testing both the GlaxoSmithKline and Merck-NewLink vaccines, while Sierra Leone and Guinea are due to announce plans soon....

WHO spokesman Christian Lindmeier, reporting on a three-day meeting of experts, told a news briefing: "Vaccine introduction is by no means a given and will depend on the results of clinical trials and recommendations from WHO's Strategy Advisory Group of Experts (SAGE) on vaccines and immunization....

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Fatality Rate Is Falling in West African Ebola Clinics

NEW YORK TIMES  by Donald G. McNeil, Jr.                 Feb. 27, 2015

SEATTLE — As the Ebola epidemic in West Africa wanes, physicians from Doctors Without Borders are confronting a mystery: More of their patients are surviving. They do not know why.

Benetha Coleman, an Ebola survivor and nurse’s aide, comforted a baby with Ebola symptoms in Liberia, as seen through a net. Credit John Moore/Getty Images

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U.S. military ends Ebola mission in Liberia

REUTERS    by  James Harding Giahyue                                                          Feb. 26, 2015

MONROVIA -- The United States military officially ended a mission to build treatment facilities to combat an Ebola outbreak in Liberia on Thursday, months earlier than expected, in the latest indication that a year-long epidemic in West Africa is waning.

Washington launched the mission five months ago and the force peaked at over 2,800 troops at a time when Liberia was at the epicenter of the worst Ebola epidemic on record....

"While our large scale military mission is ending...the fight to get to zero cases will continue and the (Joint Force Command) has ensured capabilities were brought that will be sustained in the future," U.S. Army Major General Gary Volesky....

Speaking to lawmakers during a visit to Washington on Thursday, Liberia's President Ellen Johnson Sirleaf thanked the United States for its support during the crisis.

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http://uk.reuters.com/article/2015/02/26/us-health-ebola-usa-idUKKBN0LU2HR20150226

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Diagnosing Ebola – a day in the life of a diagnostics lab in Sierra Leone

 Professor Ian Goodfellow describes an average day in an Ebola diagnostics lab, and challenges the team faced in setting it up, Courtesy of the Wells Trust Blog

BIOMED CENTRAL      by  Ian Goodfellow                                                             Feb. 25, 2015

During the first two weeks in Makeni, Sierra Leone, our focus was very much on getting the Ebola diagnostics lab operational as fast as possible. There was a real lack of diagnostic capacity in this area of the country the lab facility needed to go live prior to the opening of the treatment center.

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Ebola Doctor: Media, politicians fueled the public's fears

ASSOCIATED PRESS   by Tom McElroy                                                             Feb. 25, 2015

NEW YORK — A doctor who contracted the deadly Ebola virus and rode the subway system and dined out before he developed symptoms said the media and politicians could have done a better job by educating people on the science of it instead of focusing on their fears.

 "When we look back on this epidemic, I hope we'll recognize that fear caused our initial hesitance to respond — and caused us to respond poorly when we finally did," Dr. Craig Spencer wrote in an article published Wednesday in The New England Journal of Medicine. (See link below.)

Spencer, an emergency room physician, was diagnosed with Ebola on Oct. 23, days after returning from treating patients in Guinea with Doctors Without Borders. His was the first Ebola case in the nation's largest city, spurring an effort to contain anxieties along with the virus. He was treated at a hospital, recovered and was released on Nov. 11.

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Traditional healer called back to remove curse of first Ebola-affected village in Guinea

ASSOCIATED PRESS By YOUSSOUF BAH                       Feb. 25, 2015
MELIANDOU, Guinea (AP) — Here at ground zero of West Africa's Ebola outbreak, a local traditional healer returned to complete the removal of a curse residents believe could have been placed on their village in Guinea.

In this photo taken on Feb. 23, 2015, traditional healers, right, take part in a exorcism as villagers hand them a chicken, in Meliandou, Guinea. Here at ground zero of West Africa’s Ebola outbreak, a local traditional healer returned to complete the removal of a curse residents believe could have been placed on their village in Guinea. (AP Photo/Youssouf Bah)

It is the same village where experts believe 2-year-old Emile Ouamouno was the first person to have died from Ebola, on Dec. 28, 2013, in the outbreak that has slowed in recent months but has not been completely stamped out....Hundreds abandoned the village, believing the Ouamouno family or the entire village, was cursed, the village chief Amadou Kamano remembered.

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Report Slams U.S. Ebola Response and Readiness

NBC NEWS  by Maggie Fox                                                                               Feb. 26, 2015

The United States fumbled its response to the Ebola epidemic before it even began, neglecting experiments to make vaccines and drugs against the virus, and cutting funding to key public health agencies, a presidential commission said Thursday.

Americans focused on their own almost nonexistent risk of catching Ebola from travelers instead of pressing to help the truly affected nations, the scathing report from the Presidential Commission for the Study of Bioethical Issues says.

They've been acting against their own best interest, the commission said in its report.

"Both justice and prudence demand that we do our part in combating such devastating outbreaks. Once we recognize our humanitarian obligations and the ability of infectious diseases to travel in our interconnected world, we cannot choose between the ethical and the prudential," it reads.

"Ethics and enlightened interest converge in calling for our country to address epidemics at their source."

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Guinea's Conde replaces key minister to boost Ebola fight

REUTERS                                                                                               Feb. 25, 2015

CONAKRY - Guinean President Alpha Conde on Tuesday replaced the minister of territorial administration with an army general in a move the government said was necessary to strengthen the fight against an Ebola outbreak in the West African nation.

 A statement read on state-owned television announced the appointment of General Bourema Conde, considered to be among the president's closest allies in Guinea's army....

More than 14 months after the first Ebola case was reported in Guinea's forest region, the government still faces pockets of often violent resistance to the campaign against the epidemic, undermining its plans to rebuild the health sector and economy.

Bourema Conde replaces Alassane Conde, a civilian who had held the position since President Conde named his first government following his election in late 2010. He will continue to serve as a government minister with an advisory role to the president. None of the three men are related.
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99 Ebola cases in past week, nearly two-thirds in Sierra Leone: WHO

REUTERS                                                  Feb. 25 2015

GENEVA - Guinea, Liberia and Sierra Leone reported 99 new confirmed Ebola cases in the week to Feb. 22, down from 128 the previous week, the World Health Organization (WHO) said on Wednesday.

Sierra Leone accounted for the bulk of the latest infections with 63, signaling a halt to a steep decline recorded from December through January, followed by Guinea with 35 and Liberia just a single case, the U.N. agency said in its weekly report.

"Cases continue to arise from unknown chains of transmission," the WHO said. Sixteen of the new cases were identified in Guinea and Sierra Leone after post-mortem testing of people who died in the community "indicating that a significant number of individuals are still either unable or reluctant to seek treatment."

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http://news.yahoo.com/99-ebola-cases-past-week-nearly-two-thirds-195956152.html
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Update: Ebola Virus Disease Epidemic — West Africa, February 2015

 CDC  Weekly report                                                                    Feb. 24, 2015

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