Ebola: vaccine trials can offer ‘signs of hope’ says UN health chief

UNITED NATIONS NEWS CENTRE                                Jan. 8, 2015

GENEVA--The United Nations World Health Organization (WHO) today convened in Geneva its second ever high-level meeting on Ebola vaccines access and financing, to review the current status of clinical trials and plans for Phase II and Phase III efficacy trials.

WHO mobile lab scientists at the crossing point between Guinea and Sierra Leone, two of the countries affected by the Ebola outbreak in West Africa. Photo: WHO/Saffea Gborie

“We are here to take stock, plan the next steps, and make sure that all partners are working in tandem. We all want the momentum and sense of urgency to continue,” Dr. Margaret Chan, Director-General of WHO said as she kicked off the meeting.

The most advanced candidate Ebola vaccine is scheduled to enter Phase III efficacy clinical trials in West Africa in January/February 2015, and if shown effective – will be available for deployment a few months later.

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IMF to provide new funds to help three main Ebola-hit nations

REUTERS   by James Harding Giahyue                                                  Jan. 8, 2015

The International Monetary Fund is preparing around $150 million in additional support to Liberia, Sierra Leone and Guinea, the countries at the heart of the Ebola epidemic, the Fund's representative in Liberia told Reuters on Thursday.

"In Guinea and Sierra Leone, existing Fund financial programs are being augmented to provide more resources to these countries. In Liberia, a one-off disbursement under the Fund's Rapid Credit Facility is being considered," Charles Amo-Yartey told Reuters in an email.

The money could be made available in the first quarter of this year and would add to $130 million disbursed by the Fund in September.

Read complete story.

http://www.reuters.com/article/2015/01/08/health-ebola-imf-idUSL6N0UN3RA20150108

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Ebola: A day with the burial team

BBC      by Tulip Mazumdar                                                                                     Jan. 7, 2015
FREETOWN, Sierra Leone --

...One factor crucial to ending the outbreak is the safe burial of Ebola victims, because their bodies are particularly toxic.

The UK is funding more than 100 burial teams in Sierra Leone. Tulip Mazumdar spent the day with one of them, the Sierra Leone Red Cross Burial Team 9 in the capital Freetown. Here she describes her day....


                 The team is called to collect a body and, before it is removed, the group takes a moment to pray

Each burial team had around 10 people, including family liaison officers, disinfectant sprayers and drivers....

These were not highly trained medics or undertakers used to seeing dead bodies. They were people from the community, for example students and other volunteers. Depending on their job they are being paid approximately $10 (£6.60) a day.This is considered a very good wage in a country where most people survive on much less.

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UNMEER SRSG Pleads for Regional- Collaboration to Battle Ebola

THE DAILY OBSERVER   by Gloria T. Tamba                                                        Jan. 8, 2015

(Two stories. Scroll down.)

MONROVIA -The United Nations Mission for Ebola Emergency Response (UNMEER) Special Representative to the Secretary General (SRSG), Ismail Ould Cheikh Ahmed, has called on the Liberian government, as well as other Ebola-affected countries, for regional collaboration to battle the Ebola Virus Disease (EVD)....

 

Head of UNMEER Ismail Ould Cheikh Ahmed (second right) meets in Monrovia with Special Representative for Liberia, Karin Landgren (second left), to discuss cooperation on Ebola between the two UN entities. Photo: UNMEER/Simon Ruf

According to him, Liberia has made great progress in the fight against the deadly virus, but said that a lot needs to be done. He called on health authorities of Liberia, Guinea and Sierra Leone, the three hardest hit Ebola-affected countries in West Africa, to carry on regional collaboration by handling Ebola matters in a unique way that could eradicate the killer virus.

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Ebola Kills Nearly 500 Health Care Workers

NBC NEWS    by Maggie Fox                                      Jan. 7, 2014

The Ebola virus has infected more than 800 health care workers, killing nearly 500 of them, according to the latest numbers released by the World Health Organization Wednesday....

 The new numbers on health care workers show that doctors, nurses and other people working at Ebola treatment centers are among those at highest risk. "A total of 838 health-care workers are known to have been infected with Ebola virus disease up to the end of 4 January 2015, 495 of whom have died," WHO said in a statement.

"The marked increase from the total of 678 health-care worker infections reported last week is due to additional cases reported from Sierra Leone that have occurred since the onset of the epidemic. These are not infections that have occurred between the two most recent reporting periods."

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http://www.nbcnews.com/storyline/ebola-virus-outbreak/ebola-kills-nearly-500-health-care-workers-n281801

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Climate Mission Impossible: Scientists Say Fossil Fuels Must Go Untapped

The UCL study used an economic model to determine what percentage of each region's fossil fuel reserves should be left untouched in order to meet climate goals. Reserves are defined as fuels that could be developed given current technology and economic conditions.
EMILY M. ENG, NG STAFF. SOURCE: C. MCGLADE AND P. EKINS. NATURE

New study says vast amounts of coal, oil, and gas must be left untouched to limit global warming.

CLICK HERE - STUDY - NATURE
The geographical distribution of fossil fuels unused when limiting global warming to
2 °C

Nature 517, 187–190 (08 January 2015) doi:10.1038/nature14016

nationalgeographic.com - January 7, 2015
by Christina Nunez

Canada's tar sands need to stay in the ground, the oil beneath the Arctic has to remain under the sea, and most of the world's coal must be left untouched in order to prevent global temperatures from rising more than 2°C, a study released Wednesday says.

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Geographic information helps provide public health intelligence at mass gatherings

MEDICALNEWS TODAY                                                            Jan. 6, 2015

Infectious diseases are one of the many health issues that worry the organizers of mass gatherings, such as the Hajj and the World Cup. Geographers' tools of the trade can help event organizers to better plan, monitor and respond timely to such eventualities. The ways in which geographers gather, analyze, and visualize information provide health officials with clearer pictures of the transport routes and environmental factors that may further the spread of viruses to and from the attendees' home countries.

In Chapter 3 of the new book Health, Science and Place: A New Model, geographer and biologist Dr. Amy Blatt explains how geographic information is used for disease surveillance at mass gatherings.
Read complete article

http://www.medicalnewstoday.com/releases/287577.php?tw

Read excerpt from the book,chapter 3.

by Dr. Amy Blatt
http://link.springer.com/chapter/10.1007%2F978-3-319-12003-4_3

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What providers can learn from infectious disease outbreaks

FIERCEHEALTHCARE                 by                                                                Jan. 5. 2015

(Two items. Scroll down.)

With the Ebola crisis far from over as a new year begins, both this current threat to global health as well as past infectious disease outbreaks carry important lessons for critical care providers, according to an article in the American Journal of Critical Care.

Because new pathogens are so unpredictable, "outbreaks reinforce the importance of critical care knowledge, skill and teamwork in uncertain situations," wrote Cindy L. Munro, R.N., Ph.D., and Richard H. Savel, M.D, both editors of the AJCC. "The recent Ebola outbreak reminds us that hand-washing, personal protective equipment and pristine technique are essential."

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The Race for the Ebola Vaccine

THE DAILY BEAST  by Abby Haglage                                                                  Jan. 7, 2015

...Although a few smaller companies have become involved in the race for a vaccine, three major pharmaceutical makers are taking the lead—each pursuing a different vaccine. The trials are unprecedented for a variety of reasons, including the rapid timeline (trials of this nature generally take three to four years).

                                                      Steve Parsons-WPA Pool/Getty Images

Each individual race involves an unusual collaboration between researchers, manufacturers, and public-health entities. Together, the teams are working 24 hours a day for a product that promises much higher risk than it does profit.

Here’s what you need to know about the Ebola vaccine front-runners.

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http://www.thedailybeast.com/articles/2015/01/07/the-race-for-the-ebola-vaccine.html

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Effort on Ebola Hurt W.H.O. Chief

NEW YORK TIMES  by Somini Sengupta                                                  Jan. 7, 2015

....Now, Ebola is battering three fragile countries in Africa and with it, the W.H.O.’s standing — in large part, Dr. Chan’s critics say, because she let governments around the world steer the agency to fit their own needs, instead of firmly taking the helm as the world’s doctor in chief.

Diplomacy is an inevitable, even necessary, part of running the world’s main health organization, vital to getting fractious countries to cooperate for the sake of global health, her critics acknowledge.

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Ebola deaths top 8,000; exposures trigger health worker evacuations

Ebola: Roundup of recent developments

(Two items. Scroll down for UNMEER report.)

CENTER FOR INFECTIOUSNESS DISEASE AND POLICY   by Lisa Schnirring                              Jan. 5, 2015

As deaths in West Africa's Ebola outbreak officially topped 8,000 over the weekend, leadership of the United Nations Mission for Ebola Emergency Response (UNMEER) changed hands, and Guinea launched a new effort to battle the disease amid continuing reports of community resistance....

In other developments, Guinea's government has announced the launch of a campaign called "zero Ebola in 60 days", UNMEER said today. Guinea's Ebola case counts have been oscillating over the past several months, and in its most recent update, the WHO said it's not clear what the trend is. The first part of Guinea's campaign will start Tuesday, with expert teams traveling to six regions to assess local response efforts and form an action plan for each prefecture that dovetails with Guinea's national action plan.

UNMEER said the campaign's working groups are targeting surveillance, case management, infection control, community engagement and social mobilization, and safe burials.

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UN: Ebola kills 8,153 people in West Africa, infects 20,650

ASSOCIATED PRESS                                                                                      Jan. 5, 2015

GENEVA --The World Health Organization says at least 8,153 people have died in the Ebola outbreak in West Africa.

The Geneva-based body said Monday that the total number of confirmed, probable and suspected deaths from the disease comes from 20,656 cases in the three most affected countries — a mortality rate of 39 percent.

The U.N. health agency says 2,915 deaths have been reported from Sierra Leone, 3,471 in Liberia and 1,767 in Guinea.

Read complete story.

http://news.yahoo.com/un-ebola-kills-8-153-people-west-africa-175150599.html

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J&J, Bavarian Nordic start clinical tests in Ebola vaccine race

REUTERS     by Ben Hirschler                              Jan. 6, 2015
LONDON --Johnson & Johnson has started clinical trials of its experimental Ebola vaccine, which uses a booster from Denmark's Bavarian Nordic, making it the third such shot to enter human testing.

The initiation of the Phase I study in Britain, which had been expected about now, marks further progress in the race to develop a vaccine against a disease that has killed more than 8,000 people in West Africa since last year.

Two other experimental vaccines, one from GlaxoSmithKline and a rival from NewLink and Merck, are already in clinical development. However, the J&J vaccine offers a different approach, since it involves two separate injections.

Read complete story.

http://www.reuters.com/article/2015/01/06/us-health-ebola-vaccine-j-j-idUSKBN0KF0HH20150106

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Ebola’s legacy: After the passing

The virus will have a long-lasting impact on already poor countries

THE ECONOMIST                                                                                                      Jan. 3, 2015
When Ebola was at its worst in west Africa a few months ago, many worried that weak governments in Guinea, Liberia and Sierra Leone might be swept away by riots or the collapse of order as the virus took hold. In fact, the opposite appears to be the case. Governments have tightened their grip and are displaying authoritarian inclinations in ways rarely seen in the three young democracies....

The disease, meanwhile, continues to spread. In the week to December 21st, Guinea experienced its highest incidence of the virus since the outbreak began (see chart). In Liberia dozens of new cases have been reported along the border with Sierra Leone.

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Liberia close to beating Ebola as cases dwindle

THE GUARDIAN  by Lisa O'Caroll                                                                       Jan. 5, 2015

Liberia appears close to beating Ebola, with plans to reopen schools next month after the latest figures showed the infection rate has dwindled to just over four cases a day.


Liberian president, Ellen Johnson Sirleaf, announced that schools would reopen on 2 February. Photograph: John Moore/Getty Images

The US also plans to withdraw about half its 2,400 troops six months after the virus struck, claiming 3,400 lives.

Optimism has been increased by figures issued by the UN Mission for Ebola Emergency Response (Unmeer). They show the country had no confirmed Ebola cases on 31 December and just 91 cases in the past 21 days.

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