voanews.com - by Deborah Block - Nov 26, 2014



On Thanksgiving day in the United States, Americans give thanks for their blessings. Among them is Bobby Smith, who emigrated to here 25 years ago from Sierra Leone. To give back, three years ago Smith began a small volunteer organization, Hope for Lives in Sierra Leone, to help the disadvantaged in his homeland -- one of the poorest countries in the world. As VOA’s Deborah Block reports, he now is sending medical supplies to help combat Ebola, which continues to devastate Sierra Leone.

http://www.voanews.com/media/video/sierra-leonean-in-us-sends-medical-supplies-home-to-combat-ebola/2535979.html

by Shalini Saxena - Nov 30 2014 - http://arstechnica.com

We know what antibodies stop it in its tracks—we now know where they attach.

The latest Ebola outbreak has dwarfed any that have occurred since the discovery of the virus in 1976; previous outbreaks have had lethality rates of up to 90 percent. Yet no vaccines or therapies are currently approved for human use, which limits our ability to treat patients and contain the outbreak. Mixtures of monoclonal antibodies (see sidebar) are a potential treatment option that has been used experimentally.

by Elizabeth Barber - Dec. 1, 2014 - time.com

The U.N. mission is urging that the longer the disease is allowed to storm West Africa, the more likely it is that the virus will reappear elsewhere in the world.

The head of the U.N. Ebola mission in West Africa has said there is a “huge risk” of the Ebola outbreak expanding beyond the hard-hit region.

https://time.com/3611314/u-n-ebola-global-threat-anthony-banbury-bbc/

BBC   by Andrew Harding                                    Dec. 2, 2014

FREETOWN, Sierra Leone --

... "By now, everyone knows about Ebola; and nobody with symptoms should, logically, be dying at home or on the street anymore.

Sometimes suspected Ebola cases are not reported to the health authorities

They should all have been taken to hospital.

But to understand why that is not happening, all you have to do is drive to any of the impoverished suburbs of Freetown..."

Read complete article

http://www.bbc.com/news/world-africa-30279932

With trials under way, scientists are working out how to give vaccines in affected regions

NATURE   By Ewan Callaway                                                                                                 Dec. 2, 2014

Safety trials of Ebola vaccines are starting to return results: at least one is known to be safe and to summon an immune response against the virus.

The challenge now is to use the results to guide the larger studies that will reveal whether the vaccines work.

“The immune responses are there,” says infectious-disease researcher Adrian Hill, director of the Jenner Institute in Oxford, UK. “The tough call is whether they’re enough to protect humans against Ebola.”

Read complete story

http://www.nature.com/news/positive-results-spur-race-for-ebola-vaccine-1.16468

DISCOVER MAGAZINE    By Kari Lydersen                                                                              Dec. 2, 2014
.....redicting the trajectory of Ebola rather than playing catching-up could do much to help prevent and contain the disease. Some experts have called for prioritizing mobile treatment units that can be quickly relocated to the spots most needed. Figuring out where Ebola is likely to strike next or finding emerging hot spots early on would be key to the placement of these treatment centers.

But such modeling requires data, and lots of it.  And for stressed healthcare workers on the ground and government and non-profit agencies scrambling to combat a raging epidemic, collecting and disseminating data is often not a high priority.

ASSOCIATED PRESS                                                                                                        Dec. 2, 2014 

BETHESDA, Maryland  — Declaring the "fight is nowhere close to being over," President Barack Obama on Tuesday heralded strides in the effort to confront Ebola in West Africa and in protecting the U.S. against the spread of the deadly virus. He said squelching the disease remains an urgent priority even if the American public's attention has shifted elsewhere.

"We cannot let down our guard, even for minute," Obama said. "We can't just fight this epidemic, we have to extinguish it."

Obama spoke after touring the National Institutes of Health in Washington's Maryland suburbs where he witnessed advances in Ebola-fighting research. He highlighted the NIH's progress in developing an Ebola vaccine, calling the initial results "exciting" while cautioning that there are "no guarantees" about the vaccine's ultimate success.

NIH researchers last week reported that the first safety study of a vaccine candidate found no serious side effects, and that it triggered signs of immune protection in 20 volunteers. U.S. health officials are planning much larger studies in West Africa to try to determine if the shots really work...

IRIN                                                              Dec. 1, 2014

DAKAR--It is next to impossible to avoid physical contact in an overcrowded prison. In Sierra Leone, heavily congested jails and a worsening Ebola outbreak make a potentially lethal combination. So how do you keep inmates safe?

                          Decongesting prisons in Sierra Leone to lower Ebola threat.Photo: Hannah McNeish/IRIN

Some of the safeguards against the virus are: A 21-day quarantine for fresh detainees before joining the old timers; training prison health workers and inmate leaders on Ebola prevention; and providing health and safety education and equipment.

Such measures, and others, have so far helped keep the virus out of Sierra Leone’s 17 prisons and three juvenile offenders’ homes, said Mambu Feika, head of NGO Prison Watch Sierra Leone (PWSL), which is spearheading a three-month programme to prevent Ebola transmission in prisons.

See full story

WASHINGTON POST-- By Lena H. Sun                                                                                         Dec. 2, 2014

WASHINGTON --U.S. officials have designated 35 hospitals around the country to care for Ebola patients, part of the Obama administration’s effort in the past two months to improve domestic preparedness to cope with the deadly virus that has ravaged West Africa.

 

A nurse walks down a hallway alongside a patient care room in a new custom-built bio-containment unit for potential Ebola cases at Mount Sinai Hospital, in New York. (John Minchillo/AP)

 The hospitals were chosen by state health officials and hospital executives and assessed by infection control teams from the Centers for Disease Control and Prevention to make sure they have adequate staff, equipment, training and resources “to provide the extensive treatment necessary to care for an Ebola patient,” according to a senior administration official.

World Bank Meanwhile lowers growth forecasts.

(See link below to World Bank Report)

ASSOCIATED PRESS                                                                                               Dec. 2, 2014
By JONATHAN PAYE-LAYLEH and SARAH DiLORENZO

MONROVIA, Liberia (AP) — The international response to Ebola is still too slow and piecemeal, Doctors Without Borders warned Tuesday, as officials said the disease is crippling the economies of the three West African countries hardest hit....

"Foreign governments have focused primarily on financing or building Ebola case management structures, leaving staffing them up to national authorities, local health care staff and NGOs (non-government organizations) which do not have the expertise required to do so," said the group, which is a primary provider of treatment in the outbreak, said in a statement Tuesday.

It reiterated its call for countries with biological-disaster response teams to deploy them.

CNN    BY Laura Smith-Spark                                                                                                   Dec. 2, 2014
Spain is officially clear of Ebola, the World Health Organization declared Tuesday, after no new cases were reported since a nurse's assistant who contracted the virus there tested negative for it.

Spanish nurse Teresa Romero after being discharged from hospital on November 5, 2014 in Madrid, Spain

Since then, 42 days have passed -- double the maximum known incubation period for the virus -- without another case, allowing Spain to be declared free of Ebola.

Spanish authorities had been monitoring 87 people who came into contact with healthcare worker Teresa Romero Ramos, 15 of whom were considered high-risk and were quarantined at a Madrid hospital, WHO said.

Another 145 hospital employees who helped care for Romero during her month-long stay at the Carlos III Hospital were also monitored.

NEW YORK TIMES  By Sheri Fink and  Somini Sengupta                                                       Dec. 2, 1014

GENEVA — The World Health Organization expressed doubt on Monday about achieving important United Nations benchmarks in battling Ebola, saying the year-end goals of isolating and treating all patients and safely burying all the dead would be major challenges.

REUTERS  -- By Roberta Rampton                                                                      Dec. 2, 2014

WASHINGTON --President Barack Obama on Tuesday will press Congress to approve $6.18 billion in emergency funding to help fight the Ebola outbreak in West Africa and prepare U.S. hospitals to handle future cases.

Most of the request is aimed at the immediate response to the disease at home and abroad. But the package also includes $1.5 billion in contingency funds - money that could become a target if lawmakers decide to trim the bill.

"That is the part of the package that is most at risk," said Sam Worthington, president of InterAction, an alliance of U.S. non-governmental aid groups.

Read complete story.

WHO targets on isolating patients and medical burials missed as NGO warns virus has reduced country to ‘a nation of mere beggars’

THE GUARDIAN   By  Lisa O'Carroll                                                                                           Dec. 1, 2014

FREETOWN --SIERRA Leone-- 
Ebola continues to surge in Sierra Leone, with the number of cases quintupling in Freetown alone in the past two months, according to new figures.

A health worker gives a drink to a young patient at the Kenema treatment centre, Sierra Leone. Photograph: Francisco Leong/AFP/Getty Images