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Five million children out of school in West Africa due to Ebola

REUTERS-by  Misha Hussain                                   Dec. 3, 2014

DAKAR, Senegal   - Some five million children are out of school in Guinea, Liberia and Sierra Leone because of the deadly Ebola outbreak, according to a report by the Global Business Coalition for Education.

A man walks by a mural with health instructions on treating the Ebola virus, in Monrovia, November 18, 2014. Credit: Reuters/James Giahyue

Schools and other public buildings have been closed because they are believed to increase the spread of the virus. Many are now used as holding centers for Ebola patients.

The report, co-written with A World at School, said being out of school can have a crippling impact on vulnerable children, especially girls, who are more likely to face high-risk situations as a result, including early marriage and pregnancy.

If schools are not reopened, the most vulnerable children will become trapped in a cycle of poverty with devastating consequences for their health and economic development, the report said.

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Sierra Leonean in US Sends Medical Supplies Home to Combat Ebola

voanews.com - by Deborah Block - Nov 26, 2014



On Thanksgiving day in the United States, Americans give thanks for their blessings. Among them is Bobby Smith, who emigrated to here 25 years ago from Sierra Leone. To give back, three years ago Smith began a small volunteer organization, Hope for Lives in Sierra Leone, to help the disadvantaged in his homeland -- one of the poorest countries in the world. As VOA’s Deborah Block reports, he now is sending medical supplies to help combat Ebola, which continues to devastate Sierra Leone.

http://www.voanews.com/media/video/sierra-leonean-in-us-sends-medical-supplies-home-to-combat-ebola/2535979.html

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Finding the Ebola virus’ vulnerable points

Three copies of the Ebola glycoprotein (blue) with antibodies (yellow) latched on to them. Picture by Stanfordby Shalini Saxena - Nov 30 2014 - http://arstechnica.com

We know what antibodies stop it in its tracks—we now know where they attach.

The latest Ebola outbreak has dwarfed any that have occurred since the discovery of the virus in 1976; previous outbreaks have had lethality rates of up to 90 percent. Yet no vaccines or therapies are currently approved for human use, which limits our ability to treat patients and contain the outbreak. Mixtures of monoclonal antibodies (see sidebar) are a potential treatment option that has been used experimentally.

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In Liberia, Ebola Shifts From Cities To Villages

November 30, 2014 - Rachel Martin - npr.org - Copyright © 2014 NPR

Liberia has been a death zone for those exposed to the Ebola virus. NPR's Rachel Martin speaks with correspondent Kelly McEvers about what she saw on the ground, and what she will find hard to forget.

RACHEL MARTIN, HOST:

The death toll in the largest Ebola outbreak in history continues to rise in West Africa. Just this past week, the World Health Organization reported 600 new cases in the three hardest hit countries - Guinea, Sierra Leone and Liberia. Liberia had been the epicenter of the outbreak. But now the country with the largest number of victims is neighboring Sierra Leone. NPR reporters have been covering the story in both countries. NPR's Kelly McEvers is about to finish nearly two weeks in Liberia. She joins us on the line. Hi, Kelly.

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http://www.npr.org/2014/11/30/367544593/in-liberia-ebola-shifts-from-cities-to-villages

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U.N. Mission Warns That Ebola Still Poses ‘Huge’ Global Threat

A mother and child stand atop their mattresses in a classroom now used as Ebola isolation ward on Aug. 15, 2014, in Monrovia, Liberiaby Elizabeth Barber - Dec. 1, 2014 - time.com

The U.N. mission is urging that the longer the disease is allowed to storm West Africa, the more likely it is that the virus will reappear elsewhere in the world.

The head of the U.N. Ebola mission in West Africa has said there is a “huge risk” of the Ebola outbreak expanding beyond the hard-hit region.

https://time.com/3611314/u-n-ebola-global-threat-anthony-banbury-bbc/

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WHO Says Liberia, Guinea Meeting Ebola Targets

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Ebola crisis: Struggling to change behaviour in Sierra Leone

BBC   by Andrew Harding                                    Dec. 2, 2014

FREETOWN, Sierra Leone --

... "By now, everyone knows about Ebola; and nobody with symptoms should, logically, be dying at home or on the street anymore.

Sometimes suspected Ebola cases are not reported to the health authorities

They should all have been taken to hospital.

But to understand why that is not happening, all you have to do is drive to any of the impoverished suburbs of Freetown..."

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http://www.bbc.com/news/world-africa-30279932

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Positive results spur race for Ebola vaccine

With trials under way, scientists are working out how to give vaccines in affected regions

NATURE   By Ewan Callaway                                                                                                 Dec. 2, 2014

Safety trials of Ebola vaccines are starting to return results: at least one is known to be safe and to summon an immune response against the virus.

The challenge now is to use the results to guide the larger studies that will reveal whether the vaccines work.

“The immune responses are there,” says infectious-disease researcher Adrian Hill, director of the Jenner Institute in Oxford, UK. “The tough call is whether they’re enough to protect humans against Ebola.”

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http://www.nature.com/news/positive-results-spur-race-for-ebola-vaccine-1.16468

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To halt Ebola's spread, researchers race for data

DISCOVER MAGAZINE    By Kari Lydersen                                                                              Dec. 2, 2014
.....redicting the trajectory of Ebola rather than playing catching-up could do much to help prevent and contain the disease. Some experts have called for prioritizing mobile treatment units that can be quickly relocated to the spots most needed. Figuring out where Ebola is likely to strike next or finding emerging hot spots early on would be key to the placement of these treatment centers.

But such modeling requires data, and lots of it.  And for stressed healthcare workers on the ground and government and non-profit agencies scrambling to combat a raging epidemic, collecting and disseminating data is often not a high priority.

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Obama: Ebola still priority as public focus shifts

ASSOCIATED PRESS                                                                                                        Dec. 2, 2014 

BETHESDA, Maryland  — Declaring the "fight is nowhere close to being over," President Barack Obama on Tuesday heralded strides in the effort to confront Ebola in West Africa and in protecting the U.S. against the spread of the deadly virus. He said squelching the disease remains an urgent priority even if the American public's attention has shifted elsewhere.

"We cannot let down our guard, even for minute," Obama said. "We can't just fight this epidemic, we have to extinguish it."

Obama spoke after touring the National Institutes of Health in Washington's Maryland suburbs where he witnessed advances in Ebola-fighting research. He highlighted the NIH's progress in developing an Ebola vaccine, calling the initial results "exciting" while cautioning that there are "no guarantees" about the vaccine's ultimate success.

NIH researchers last week reported that the first safety study of a vaccine candidate found no serious side effects, and that it triggered signs of immune protection in 20 volunteers. U.S. health officials are planning much larger studies in West Africa to try to determine if the shots really work...

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