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Offline: A pervasive failure to learn the lessons of Ebola

THE LANCET by Richard Horton                         Sept. 12, 2015

LONDON-- Post-Ebola reverie has given birth to a plethora of expert panels to consider what went wrong. The latest parade of global health specialists appointed to learn lessons gathered at the Wellcome Trust in London last week.
 Under the auspices of the US Institute of Medicine (IOM), a Commission to “deliberate and evaluate options to strengthen global, regional, and local systems to better prepare, detect, and respond to epidemic diseases” spent 2 days amassing evidence.

 There was no shortage of experience brought to bear on these important matters. Here were Margaret Chan, Jeremy Farrar, Ilona Kickbusch, David Heymann, Larry Gostin, Joy Phumaphi, Joanne Liu, and Peter Piot all wrestling with a seemingly intractable challenge. The statements offered to the Commission were arresting. But  the purpose of the meeting was not to talk. It was to identify the best system for an epidemic response....
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http://www.thelancet.com/journals/lancet/article/PIIS0140-6736%2815%2900152-X/fulltext

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Grim Snapshot Reveals Complex Health Issues for Ebola Survivors [Infographic]

(CLICK ON IMAGE TO ENLARGE)

submitted by George Hurlburt

Sleeplessness, along with abdominal and joint pain are common even months after recovery from the dreaded virus

scientificamerican.com - by Dina Fine Maron - September 9, 2015

The first snapshot of health complications facing Ebola survivors in Sierra Leone presents a dismal picture of their road to recovery. A new study has found that up to four months after blood tests indicated that they were Ebola-free, more than half of survivors continue to suffer from joint pain, headaches or muscle pain. And more than 40 percent of survivors complain of sleeplessness and visual problems. Perhaps most worryingly, almost all the survivors—96 percent—reported being rejected by their communities after they were released from the hospital. The majority said they were still too scared to return home.

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WHO Vaccine-Preventable Diseases: Monitoring System - Country Summaries

                                       

apps.who.int

WHO Vaccine-Preventable Diseases: Monitoring System
(Click on the country of interest - then click "OK")
http://apps.who.int/immunization_monitoring/globalsummary

Country Summaries - WHO UNICEF Review of National Immunization Coverage, 1980-2014
(Click on the country of interest)
http://apps.who.int/immunization_monitoring/globalsummary/wucoveragecountrylist.html

 

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Guinea passes one week with no new Ebola cases: WHO

AFP   Sept. 9, 2015

Geneva -- Guinea has notched up a week without a new case of Ebola, a first since March 2014, the head of the UN's response to the epidemic, Bruce Aylward, said on Wednesday.

Health workers with a patient under quarantine at the Nongo Ebola treatment centre in Conakry, Guinea on August 21, 2015 (AFP Photo/Cellou Binani)

"As of today, they have gone seven days without a (new) case of Ebola," said Aylward, the World Health Organization's special envoy for the epidemic.

"That is the longest period since March of last year that Guinea has gone without an Ebola case," he added.

There are two people in the country who have Ebola, but they tested postive before September 2.

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http://news.yahoo.com/guinea-passes-one-week-no-ebola-case-142016881.html


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Survey Finds Many Physicians Overestimate Their Ability to Assess Patients’ Risk of Ebola

massgeneral.org - August 27, 2015

While most primary care physicians responding to a survey taken in late 2014 and early 2015 expressed confidence in their ability to identify potential cases of Ebola and communicate Ebola risks to their patients, only 50 to 70 percent of them gave answers that fit with CDC guidelines when asked how they would care for hypothetical patients who might have been exposed to Ebola. In addition, those who were least likely to encounter an Ebola patient – based on their location and characteristics of their patients – were most likely to choose overly intense management of patients actually at low risk.  The results of the survey, conducted by a team of Massachusetts General Hospital (MGH) investigators, have been published online in the Journal of General Internal Medicine.

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CLICK HERE - RESEARCH - Ebola Risk and Preparedness: A National Survey of Internists 

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CDC - HHS - Ebola Concept of Operations (ConOps) Planning Template

Source:Centers for Disease Control and Prevention (CDC) - Date Published:08/20/2015

Annotation:This 38-page document provides a standard format for creating an Ebola Concept of Operations (ConOps) plan at the state, territorial, or major metropolitan area government level. It provides information on measures local governments, agencies, and organizations can take to support the plan. The ConOps in the template describes strategic, high-level considerations for establishing a regional tiered system to safely and effectively manage persons under investigation (PUIs) or patients confirmed with Ebola.

(38 page .PDF document)
URL: http://www.cdc.gov/phpr/documents/ebola-concept-of-operations-planning-template-8-20-2015.pdf

Authors:Dugas, Robert; Lamoureux, Joe; Mangieri, William; et al.
Type:Guideline/Assessment Tool
ID:11129. From Disaster LitTM, a database of the U.S. National Library of Medicine.

http://disasterlit.nlm.nih.gov/record/11129

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Mano River Union (MRU) Countries Recommend Information Sharing

thenewdawnliberia.com - by Ben P. Wesee - Editing by Jonathan Browne -September 1, 2015

The four Mano River Union or MRU countries – Liberia, Sierra Leone, Guinea and Ivory Coast have issued a joint communiqué in Monrovia, calling for information sharing, experiences and good practices during and after health emergencies in order to collaborate and network with local and international partners in the sub-region.

In a just ended conference here on the Ebola Virus Disease or EVD, the MRU countries also advanced several recommendations. Delegates from the four countries recommended in the communiqué a need to develop a harmonized framework for adherence to ethical standards during health disasters with appropriate and approved mechanisms for vaccines, therapeutic agents and testing methods.

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(ALSO SEE RELATED ARTICLE HERE)

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Interagency Collaboration on Ebola - Situation Report - 1 September 2015

                                                       

Ebola Situation Reports:

CLICK HERE -  Interagency Collaboration on Ebola - Situation Report - 1 September 2015 (7 page .PDF report)

CLICK HERE - Report Archives - Interagency Collaboration on Ebola

Note:

The numbers of suspected Ebola cases have increased by 2 in Guinea, and by 6 in Sierra Leone per the Aug. 30 data as compared to the August 29 data.

August 30 data (Published September 1)
http://apps.who.int/gho/data/view.ebola-sitrep.ebola-summary-20150901?lang=en

August 29 data (Published August 31)
http://apps.who.int/gho/data/view.ebola-sitrep.ebola-summary-20150831?lang=en

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Scientists Discover New Use for an Old Therapy Inhibiting Deadly Pathogens Including Ebola and Anthrax

                                                     

CLICK HERE - RESEARCH - Identification of agents effective against multiple toxins and viruses by host-oriented cell targeting

prweb.com - by Cynthia Lujan - September 1, 2015

A new host-based therapy for Ebola, anthrax and other deadly infectious diseases has been discovered by researchers at the Keck Graduate Institute and its collaborators. The discovery has the potential to speed to market treatments for previously untreatable diseases.

The findings were published online on August 27 by Scientific Reports, an open access research journal from the publishers of Nature.

The lead authors of the story were Leoor Zilberminitz and William Leonardi, doctoral students in KGI laboratory of assistant professor Mikhail Martchenko. The researchers screened a library of 1,581 drugs previously approved by the FDA for in vitro protection of mammalian cells against Bacillus anthracis lethal toxin and diphtheria toxin, which normally kill 50-70% of unprotected cells. They then investigated the 1% most promising compounds that both provided the best protection against the two toxins and were not toxic to uninfected cells.

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Guinea Extends Ebola Ring Vaccine Trial to Sierra Leone

allafrica.com - August 24, 2015

Freetown — The Guinean Ebola Ring Vaccine Trial has been extended to Sierra Leone as a move to stop the transmission across the region.

Addressing participants in the opening ceremony of the training session at the Brookfields Hotel Conference Hall in Freetown, the WHO Ebola Technical Coordinator Sierra Leone, Dr. Margaret Lamumu said prior to the extension of the vaccine to Sierra Leone the Ministry of Health and Sanitation and WHO Joint Team visited five sites to make available the vaccine study, adding that expert trainers from the UK were targeted to do the training. . . .

. . . The Chief Medical Officer, Dr. Brima Kargbo said the use of the vaccine would help break the chain of transmission, stressing the need to work collectively as a team to control the spread of the disease.

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(CLICK HERE - For Additional Information)

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