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CDC - HHS - Ebola Concept of Operations (ConOps) Planning Template

Source:Centers for Disease Control and Prevention (CDC) - Date Published:08/20/2015

Annotation:This 38-page document provides a standard format for creating an Ebola Concept of Operations (ConOps) plan at the state, territorial, or major metropolitan area government level. It provides information on measures local governments, agencies, and organizations can take to support the plan. The ConOps in the template describes strategic, high-level considerations for establishing a regional tiered system to safely and effectively manage persons under investigation (PUIs) or patients confirmed with Ebola.

(38 page .PDF document)
URL: http://www.cdc.gov/phpr/documents/ebola-concept-of-operations-planning-template-8-20-2015.pdf

Authors:Dugas, Robert; Lamoureux, Joe; Mangieri, William; et al.
Type:Guideline/Assessment Tool
ID:11129. From Disaster LitTM, a database of the U.S. National Library of Medicine.

http://disasterlit.nlm.nih.gov/record/11129

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Sierra Leone Quarantines 50 Following Latest Ebola Death

VOICE OF AMERICA by James Butty  Sept. 2, 2015

 Sierra Leone Tuesday quarantined 50 people in the northern district of Kambia, where a 76 year-old woman died over the weekend from Ebola. The country had just celebrated the release from the hospital of its last known Ebola patient.

Abdulai Bayraytay, national publicity and outreach coordinator in the office of Sierra Leone’s government spokesman, told VOA the good news so far is that no one else has shown symptoms of the virus.

But Bayraytay said the woman’s death re-emphasizes the government’s warning for Sierra Leoneans to be vigilant, not intransigent....

The woman who died was supposedly sick for 5 to 10 days without the authorities knowing of her situation. Still, Bayraytay said there is a remote possibility Sierra Leone may see new cases of Ebola

Read complete story.
http://www.voanews.com/content/sierra-leone-quarantines-50-following-latest-ebola-death/2941906.html

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Mano River Union (MRU) Countries Recommend Information Sharing

thenewdawnliberia.com - by Ben P. Wesee - Editing by Jonathan Browne -September 1, 2015

The four Mano River Union or MRU countries – Liberia, Sierra Leone, Guinea and Ivory Coast have issued a joint communiqué in Monrovia, calling for information sharing, experiences and good practices during and after health emergencies in order to collaborate and network with local and international partners in the sub-region.

In a just ended conference here on the Ebola Virus Disease or EVD, the MRU countries also advanced several recommendations. Delegates from the four countries recommended in the communiqué a need to develop a harmonized framework for adherence to ethical standards during health disasters with appropriate and approved mechanisms for vaccines, therapeutic agents and testing methods.

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(ALSO SEE RELATED ARTICLE HERE)

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Interagency Collaboration on Ebola - Situation Report - 1 September 2015

                                                       

Ebola Situation Reports:

CLICK HERE -  Interagency Collaboration on Ebola - Situation Report - 1 September 2015 (7 page .PDF report)

CLICK HERE - Report Archives - Interagency Collaboration on Ebola

Note:

The numbers of suspected Ebola cases have increased by 2 in Guinea, and by 6 in Sierra Leone per the Aug. 30 data as compared to the August 29 data.

August 30 data (Published September 1)
http://apps.who.int/gho/data/view.ebola-sitrep.ebola-summary-20150901?lang=en

August 29 data (Published August 31)
http://apps.who.int/gho/data/view.ebola-sitrep.ebola-summary-20150831?lang=en

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Scientists Discover New Use for an Old Therapy Inhibiting Deadly Pathogens Including Ebola and Anthrax

                                                     

CLICK HERE - RESEARCH - Identification of agents effective against multiple toxins and viruses by host-oriented cell targeting

prweb.com - by Cynthia Lujan - September 1, 2015

A new host-based therapy for Ebola, anthrax and other deadly infectious diseases has been discovered by researchers at the Keck Graduate Institute and its collaborators. The discovery has the potential to speed to market treatments for previously untreatable diseases.

The findings were published online on August 27 by Scientific Reports, an open access research journal from the publishers of Nature.

The lead authors of the story were Leoor Zilberminitz and William Leonardi, doctoral students in KGI laboratory of assistant professor Mikhail Martchenko. The researchers screened a library of 1,581 drugs previously approved by the FDA for in vitro protection of mammalian cells against Bacillus anthracis lethal toxin and diphtheria toxin, which normally kill 50-70% of unprotected cells. They then investigated the 1% most promising compounds that both provided the best protection against the two toxins and were not toxic to uninfected cells.

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Sierra Leone: Officials Confirm New Ebola Death 6 Days After Discharging Last Known Patient

usnews.com - Associated Press (AP) - by CLARENCE ROY-MACAULAY - August 30, 2015

FREETOWN, Sierra Leone (AP) — Health officials in Sierra Leone on Sunday confirmed an Ebola death less than a week after the country's last known patient was discharged from a hospital.

Samples from the body of a 67-year-old woman who died recently in Kambia district in the country's north came back positive for the deadly disease, said chief medical officer Dr. Brima Kargbo. . . .

. . . The National Ebola Response Center had deployed teams to conduct surveillance and trace people who were in contact with the woman, said OB Sisay, the center's director.

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Guinea Extends Ebola Ring Vaccine Trial to Sierra Leone

allafrica.com - August 24, 2015

Freetown — The Guinean Ebola Ring Vaccine Trial has been extended to Sierra Leone as a move to stop the transmission across the region.

Addressing participants in the opening ceremony of the training session at the Brookfields Hotel Conference Hall in Freetown, the WHO Ebola Technical Coordinator Sierra Leone, Dr. Margaret Lamumu said prior to the extension of the vaccine to Sierra Leone the Ministry of Health and Sanitation and WHO Joint Team visited five sites to make available the vaccine study, adding that expert trainers from the UK were targeted to do the training. . . .

. . . The Chief Medical Officer, Dr. Brima Kargbo said the use of the vaccine would help break the chain of transmission, stressing the need to work collectively as a team to control the spread of the disease.

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(CLICK HERE - For Additional Information)

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CDC Updates Ebola PPE Guidance for U.S. Health Care Facilities

CDC - American Hospital Association - August 27, 2015

The Centers for Disease Control and Prevention today issued updated guidance regarding personal protective equipment for health care personnel caring for suspected and confirmed Ebola patients in U.S. health care facilities. The changes clarify the use of fluid-resistant and impermeable gowns and coveralls, and provide specifications to assist facilities in selecting and ordering the recommended garments. The updates also provide additional explanation related to PPE for confirmed Ebola patients. For more information, see the updated PPE Frequently Asked Questions.

http://news.aha.org/article/150827-cdc-updates-ebola-ppe-guidance-for-us-health-care-facilities

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Antiviral Drug May Prevent Ebola, Small Study Suggests

Health care workers deemed at high risk for infection didn't get sick after treatment with anti-flu regimen

CLICK HERE - The Lancet - Post-exposure prophylaxis against Ebola virus disease with experimental antiviral agents: a case-series of health-care workers

nlm.nih.gov - by Robert Preidt - August 25, 2015

Antiviral drugs may help protect people from developing Ebola after exposure to the deadly virus, a new case study suggests.

"We are excited to publish the first report of an antiviral-based post-exposure treatment against Ebola-virus infection in humans. We believe this work justifies further study of this postexposure treatment to protect health care workers accidentally exposed to Ebola virus in the field," lead author Dr. Michael Jacobs, of the Royal Free NHS Foundation Trust, London, said in a news release from The Lancet Infectious Diseases.

"What is more, a similar approach to treat household contacts of Ebola cases may work to prevent a major route of spread during an epidemic," he added.

(READ COMPLETE ARTICLE)

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