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Why is Delta so infectious? New lab tool spotlights little noticed mutation

New lab tool spotlights mutation that speeds spread of Delta variant

As the world has learned to its cost, the Delta variant of the pandemic coronavirus is more than twice as infectious as previous strains. Just what drives Delta’s ability to spread so rapidly hasn’t been clear, however. Now, a new lab strategy that makes it possible to quickly and safely study the effects of mutations in SARS-CoV-2 variants has delivered one answer: a little-noticed mutation in Delta that allows the virus to stuff more of its genetic code into host cells, thus boosting the chances that each infected cell will spread the virus to another cell.

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Why scientists worldwide are watching the UK's COVID infections experiences

The COVID-19 pandemic in the United Kingdom has often foreshadowed what came later elsewhere. The highly contagious Alpha variant was first detected there, and the country then reported high caseloads of the more-contagious Delta strain before this variant dispersed around the rest of the world. The United Kingdom also saw a wave of infections that seems to have preceded a similar glut now sweeping Western Europe.

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Life expectancy fell sharply in the U.S. and Russia last year because of COVID

The United States had the second-steepest decline in life expectancy among high-income countries last year during the pandemic, according to a study of death data spanning several continents

The only country studied that saw a starker overall trend was Russia.

The study, published Wednesday in The BMJ (formerly the British Medical Journal), assessed premature death in 37 countries, comparing observed life expectancy in 2020 with what would have been expected for the year based on historical trends from 2005-2019. Life expectancy dropped in 31 of these countries during the pandemic. 

The U.S. trend was among the worst.  ...

 

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