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The new BA.2 version on COVID-19 so far it doesn’t appear to be more dangerous but bears investigation

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As a new version of the highly contagious omicron variant of the coronavirus spreads in parts of Asia and Europe, the World Health Organization recommended Monday that officials begin investigating its characteristics to determine whether it poses new challenges for pandemic-weary nations.

Known as BA. 2, the new version of the virus is a descendant of the omicron variant responsible for huge surges of covid-19 in the United States and elsewhere around the globe. Virologists are referring to the original omicron variant as BA. 1.

“The BA. 2 descendant lineage, which differs from BA. 1 in some of the mutations, including in the spike protein, is increasing in many countries,” the WHO wrote on its website. “Investigations into the characteristics of BA. 2, including immune escape properties and virulence, should be prioritized independently (and comparatively) to BA. 1.”

Viruses mutate constantly, mostly in harmless ways. There is no current evidence that BA. 2 is more virulent, spreads faster or escapes immunity better than BA. 1.

Variants have come, variants have gone,” said Robert Garry, a virologist at Tulane University School of Medicine. “I don’t think there’s any reason to think this one is a whole lot worse than the current version of omicron.”

BA. 2 has been detected in India, Denmark and Britain, among other countries, according to health officials and media reports abroad. In Europe, it appears the most widespread in Denmark, but that may be because the Scandinavian nation has a robust program of sequencing the virus’s genome.

At least three cases have been found in the United States at Houston Methodist Hospital in Texas, which also is studying the genetic makeup of virus samples from its patients.

“The good news is we have only three,” said James Musser, director of the Center for Molecular and Translational Human Infectious Diseases Research at Houston Methodist. “We certainly do not see the 5 percent and more that is being reported in the U.K. now and certainly not the 40 percent that is being reported in Denmark.”

But Musser said BA. 2 deserves close attention because little is known about it yet.

“We know that omicron … can clearly evade preexisting immunity” from both vaccines and exposure to other variants of the virus, he said. “What we don’t know yet is whether son-of-omicron does that better or worse than omicron. So that’s an open question.”  ...

 

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