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La FDA approuve l'utilisation du médicament expérimental de virus Ebola

La colline 6 octobre 2014
par Sarah Ferris

Washington--la Food and Drug Administration (FDA) lundi a approuvé l'utilisation d'un médicament expérimental qui a été saluée comme l'une des meilleures chances de l'industrie pharmaceutique à lutter contre le virus Ebola.

Chimerix, une société biopharmaceutique axée sur la Caroline du Nord, a annoncé lundi qu'il a reçu l'approbation pour administrer un médicament antiviral appelé brincidofovir qui a traité avec succès le virus d'Ebola dans les tests en laboratoire.

La drogue a également été testée par les Centers for Disease Control and Prevention et le National Institutes of Health, bien qu'il ne devrait pas obtenir l'approbation pour un usage grand public jusqu'à fin 2016.

une autre drogue qui a été utilisée pour traiter les patients infectés par le virus Ebola, TKM-Ebola, a également été autorisée pour une utilisation d'urgence par la FDA... Le médicament, produit par la Canadian drugmaker Tekmira, a reçu une désignation de « fast track » et est encore en cours des essais cliniques.

voir article entier

http://thehill.com/policy/healthcare/219856-fda-approves-use-of-experimental-ebola-drug

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Ebola aide pour la Sierra Leone est proche, mais en retard sur les quais

NEW YORK TIMES, 6 octobre 2014

New York Times décrit en détail comment ont retardé la réponse non-métropolitain désorganisé, demandes d'expédition des paiements de taxes et peut-être même politique, déchargement médical fournitures assis sur les quais en Sierra Lone.

Par Adam Nossiter

, Freetown, Sierra Leone--une expédition conteneur rempli de robes de protection, gants, civières, matelas et autres fournitures médicales nécessaires pour lutter contre la Sierra Leone qui explose l'épidémie d'Ebola a été... enfermé dans un conteneur bosselé au port depuis le 9 août.

< classe p = « contenu histoire histoire-corps de texte » données-para-count = « 211 » données-total-count = « 915 » > "nous sommes toujours juste dans l'espoir (!) — qui ressemble à la mendicité — que ce conteneur doit être effacé, « un fonctionnaire a écrit dans un e-mail frénétique à ses supérieurs, quelques semaines après le conteneur arrive.

à bien des égards, le retard reflète ce que certains dans les rangs de plus en plus international fonctionnaires versant dans cette nation pour lutter contre le virus Ebola décrivent en réponse à l'épidémie de gouvernement chaotique, désorganisé.

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High risk Ebola could reach France and UK by end-October, scientists calculate

Updated with related story

Hospitalized French Nurse Released from Hospital.  ( Scroll Below)

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LONDON, Reuters - By Kate Kelland, Health and Science Correspondent   Oct. 5, 2014

Scientists have used Ebola disease spread patterns and airline traffic data to predict a 75 percent chance the virus could be imported to France by October 24, and a 50 percent chance it could hit Britain by that date.

Those numbers are based on air traffic remaining at full capacity. Assuming an 80 percent reduction in travel to reflect that many airlines are halting flights to affected regions, France's risk is still 25 percent, and Britain's is 15 percent.

"It's really a lottery," said Derek Gatherer of Britain's Lancaster University, an expert in viruses who has been tracking the epidemic - the worst Ebola outbreak in history.

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Man taken off flight from Belgium does not have Ebola

Phildalphie Inquirer    Last updated: Sunday, October 5, 2014, 7:33 AM

By Erin Arvedund 

Philadelphia --The Centers for Disease Control and Prevention announced Saturday night that the sick passenger taken from United Flight 998 at Newark Liberty International Airport to be tested for Ebola did not have the virus in his system.

After The Boeing 777, which had arrived from Brussels, Belgium, with 253 passengers and 14 crew members, CDC officials in hazmat suits and officers from the Port Authority Police Department boarded the plane, said department spokeswoman Erica Dumas.

... the sick passenger - who had been vomiting - was taken to Newark's University Hospital to be checked out.

Several hours later, the CDC announced that the patient had been evaluated "in coordination with federal, state, and local public health officials" and the tests indicated he was not infected with the Ebola virus, said CDC spokeswoman Sharon Hoskins.

In fact, he had a "minor treatable condition unrelated to Ebola," the New Jersey Department of Health said. The nature of that condition was not disclosed.

Read full story

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OUT OF CONTROL: How the world’s health organizations failed to stop the Ebola Disaster

WASHINGTON POST's  detailed front page account of how the Ebola epidemic got out of control in West Africa.  Oct. 5, 2014

     by Lena Sun, Bradly Dennis, Lenny Bernstein and Joel Achenbach

The glow from a crematorium lights the sky as the bodies of people who died from Ebola are cremated last month in Monrovia

---Michel Du Cille, THE WASHINGTON POST

.... "The virus easily outran the plodding response. The WHO, an arm of the United Nations, is responsible for coordinating international action in a crisis like this, but it has suffered budget cuts, has lost many of its brightest minds and was slow to sound a global alarm on Ebola. Not until Aug. 8, 4 1 ⁄ 2 months into the epidemic, did the organization declare a global emergency. Its Africa office, which oversees the region, initially did not welcome a robust role by the CDC in the response to the outbreak.

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U.S. nurses say they are unprepared to handle Ebola patients

REUTERS                         Oct 3. 2014

CHICAGO (Reuters) - Nurses, the frontline care providers in U.S. hospitals, say they are untrained and unprepared to handle patients arriving in their hospital emergency departments infected with Ebola.

Many say they have gone to hospital managers, seeking training on how to best care for patients and protect themselves and their families from contracting the deadly disease....

The U.S. Centers for Disease Control and Prevention has repeatedly said that U.S. hospitals are prepared to handle such patients. Many infectious disease experts agree with that assessment.

... Texas Health Presbyterian Hospital in Dallas that is now caring for the first Ebola patient to be diagnosed in this country had completed Ebola training just before Thomas Eric Duncan arrived in their emergency department on Sept. 26. But despite being told that Duncan had recently traveled from Liberia, hospital staff failed to recognize the Ebola risk and sent him home, where he spent another two days becoming sicker and more infectious.

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As U.S. Ebola Fears Widen, Reports of Possible Cases Grow

NEW YORK TIMES                 OCT. 5 2014

by and

 ....Since Eobla began spreading rapidly across West Africa this summer, the C.D.C. said, it has assessed more than 100 possible cases in the United States but only the Dallas case has been confirmed.

But increased attention about the virus has jangled nerves around the country, particularly among West African immigrant communities and recent travelers to that region, and placed health care workers on a kind of high alert. “We expect that we will see more rumors, or concerns, or possibilities of cases,” Dr. Thomas R. Frieden, director of the federal C.D.C., said Saturday. “Until there is a positive laboratory test, that is what they are — rumors and concerns.”

...

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Dallas Hospital Alters Account, Raising Questions on Ebola Case

NEW YORK TIMES          Oct. 3, 2014

DALLAS TEX.      

On Thursday, the hospital, Texas Health Presbyterian Hospital in Dallas, released a statement essentially blaming a flaw in its electronic health records system for its decision to send the patient — Thomas E. Duncan, a Liberian national visiting his girlfriend and relatives in the United States — home the first time he visited its emergency room, Sept. 25. It said there were separate “workflows” for doctors and nurses in the records so the doctors did not receive the information that he had come from Africa.

But on Friday evening, the hospital effectively retracted that portion of its statement, saying that “there was no flaw” in its electronic health records system. The hospital said “the patient’s travel history was documented and available to the full care team in the electronic health record (E.H.R.), including within the physician’s workflow.”

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Texas Ebola Watch Eyes 50 People, 10 at 'High Risk'

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Ebola Victim's Air Journey shows weak spots in screening.

NEW YORK TIMES              October 3, 2014

MONROVIA, Liberia — The arrival in the United States of a Liberian man infected with the Ebola virus shows how difficult it is to control or restrict the disease from spreading, and how porous current procedures are in a world of globalized air travel.

Liberian officials said on Thursday that they planned to prosecute the passenger, Thomas E. Duncan, for lying on an airport questionnaire about not having contact with a person infected with Ebola before his travel — a pivotal part of the country’s screening process.

Mr. Duncan took three planes as he flew from Monrovia, the Liberian capital, to Dallas last month, connecting in Brussels and Washington.

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