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Treatment with hyperimmune equine immunoglobulin or immunoglobulin fragments completely protects rodents from Ebola virus infection
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Treatment with hyperimmune equine immunoglobulin or immunoglobulin fragments completely protects rodents from Ebola virus infection
Wed, 2016-04-13 07:35 — davidmcRecent successes with monoclonal antibody cocktails ZMapp
TM
and MIL77 against Ebola virus (EBOV) infections have reignited interest in antibody-based therapeutics. Since the production process for monoclonal antibodies can be prolonged and costly, alternative treatments should be investigated.
Ebola virus (EBOV) is a pathogen from the Filoviridae family, and is capable of causing severe hemorrhagic fever in humans and non-human primates. Past outbreaks of EBOV disease (EVD) were sporadic, unpredictable and localized to remote regions of central Africa, with the death toll reaching up to 90%1.
see more at: http://www.nature.com/articles/srep24179
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