Study finds 'mixing and matching' boosters safe, but Moderna, Pfizer are best

Study finds 'mixing and matching' boosters safe, but Moderna, Pfizer Receiving a booster dose of a different vaccine than what was initially administered is safe and effective, though people who received Johnson & Johnson's vaccine may get more benefit from a booster Nathaniel Weixel TheHill

eceiving a booster dose of a different vaccine than what was initially administered is safe and effective, though people who received Johnson & Johnson's vaccine may get more benefit from a booster of an mRNA vaccine such as Pfizer's or Moderna's, according to data released Wednesday.

A highly anticipated preprint study on "mixing and matching" vaccines from the National Institutes of Health found that boosting with any of the three vaccines currently licensed or authorized for emergency use in the U.S. will generate an immune response.

However, people who received a booster dose of either the Moderna or Pfizer vaccines had a higher increase in their antibody responses more often than those who received an extra dose of J&J, according to the study, which has not yet been peer reviewed.  ...