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Ebola Assay Card | Elisa-Based Diagnostic - Google Science Fair

submitted by Gavin Macgregor-Skinner

Temperature-Independent, Portable, and Rapid Field Detection of Ebola via a Silk-Derived Lateral-Flow System

googlesciencefair.com - 2015

I developed a “stable and stored at room temperature” Ebola Assay Card, applicable as an ELISA-based diagnostic for diseases such as HIV, Lyme and certain cancers, that will allow for water-activated, timed-release detection of Ebola antigens, with detection limits that are analogous to current sandwich ELISA techniques. Reagents become chemically “stabilized” when mixed into silk, which enables them to remain “chemically active” without refrigeration. This Ebola Assay Card will allow for shipment and storage without refrigeration, and provide detection of the Ebola viral antigens based on color change in as little as 30 minutes.

(CLICK HERE FOR ADDITIONAL INFORMATION)

 

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Fighting Ebola With a Palm-Sized DNA Sequencer

submitted by George Hurlburt

      

Raymond Koundouno using a MinION - Sophie Duraffour

The MinION, a pocket-sized, USB-powered sequencing machine, lets scientists track the spread of deadly diseases in real-time.

theatlantic.com - by Ed Yong - September 16, 2015

. . . Unlike rival sequencers, which are as big as microwaves or fridges, the MinION is the size of a chocolate bar. . . . These devices quite literally bring the power of modern genomics to the palm of your hand. And at a cost of just $1,000, they herald a new era where sequencing moves away from well-equipped institutions and into places where it is most needed, from hospitals to epidemic-afflicted hot zones.

(READ COMPLETE ARTICLE)

(CLICK HERE - MinION - Oxford Nanopore Technologies)

(CLICK HERE - YouTube - MinION - Oxford Nanopore Technologies)

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Feds to end Ebola screening for air travelers from Liberia

USA TODAY by Bart Jansen                           Sept. 19, 2015

WASHINGTON – Federal authorities will end mandatory Ebola screening Monday for travelers from Liberia to five U.S. airports, but will continue to scrutinize travelers from Sierra Leone and Guinea, federal officials announced Friday.

The Department of Homeland Security's Customs and Border Protection had provided extra screening for more than 30,000 travelers during the past year, after an outbreak of the often fatal disease in West Africa.....

Customs and Border Protection and the Centers for Disease Control and Prevention agreed to remove Liberia from the list of countries subject to enhanced visa and port-of-entry screening, effective Monday....

The U.S. will maintain extra screening for travelers from Sierra Leone and Guinea, which still see a handful of new cases each week, and for people who traveled through those countries during the previous three weeks.

Read complete story.
http://www.usatoday.com/story/news/2015/09/18/ebola-travel-airport-screening-liberia-sierra-leone-guinea-customs-border-protection/72398942/

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Social Vulnerability and Ebola Virus Disease in Rural Liberia

      

Clusters of social vulnerability in rural Liberia, by district. Social vulnerability of each cluster of districts can be loosely ranked from most to least vulnerable as: Cluster 1, food quality, displaced persons, disabled, dependent populations; Cluster 3, food quantity, food quality, lack of access to land/free medical care; Cluster 4, food quantity, disabled dependent populations and Cluster 5, water quality/proximity to medical care; and finally, Cluster 2, no strong vulnerability scores.

CLICK HERE - Social Vulnerability and Ebola Virus Disease in Rural Liberia

CLICK HERE - Social Vulnerability and Ebola Virus Disease in Rural Liberia (14 page .PDF file)

srs.fs.usda.gov - by Zoe Hoyle - September 15, 2015

A newly published research study by U.S. Forest Service researchers demonstrates that the social vulnerability indices used in climate change and natural hazards research can also be used in other contexts such as disease outbreaks.

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Quarantines return as Ebola makes comeback in Sierra Leone

REUTERS    Sept.14, 2015
FREETOWN — Health authorities quarantined hundreds of people in northern Sierra Leone on Monday after a 16-year-old girl died of Ebola in an apparent case of sexual transmission, the first confirmed death from the virus in the district for nearly six months.

Sierra Leone celebrated last month when it discharged the last remaining Ebola patient from its treatment centers. But since then a new spate of cases has erupted, leaving two dead and five people in treatment.

The teenage girl, Kadiatu Thullah, died on Sunday at the International Medical Corps Ebola treatment unit, authorities said.

Emmanuel Conteh, head of the Ebola Response Centre for the district of Bombali in northern Sierra Leone, said that some 690 people in the village of Robuya where Kadiatu lived would be isolated for three weeks....it.

Conteh said health workers were investigating how the teenager got infected, since she had not traveled outside the village in years. Initial suspicions are that she had sex with an Ebola survivor.

Read complete story.

http://www.reviewjournal.com/news/nation-and-world/quarantines-return-ebola-makes-comeback-sierra-leone

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CDC - Care of a Neonate Born to a Mother who is Confirmed to have Ebola, is a Person under Investigation, or has been Exposed to Ebola

cdc.gov

Interim Guidance for U.S. Hospitals on the Care of a Neonate Born to a Mother who is Confirmed to have Ebola, is a Person under Investigation (PUI), or has been Exposed to Ebola

Who this is for: Healthcare professionals working with neonates in labor and delivery, neonatal intensive care units, newborn nurseries, and other settings in U.S. hospitals.

What this is for: Guidance on how to care for neonates born to mothers exposed to Ebola virus, PUIs, or with confirmed Ebola.

How to use this: This guidance is intended to help U.S. hospitals develop plans for treating neonates born to PUIs or to mothers with confirmed Ebola. Note: Ideally, these mothers and neonates will be cared for in Ebola assessment hospitals (if the mother is a PUI) or Ebola treatment centers (if the mother is confirmed to have Ebola.)1

CLICK HERE - Care of a Neonate Born to a Mother who is Confirmed to have Ebola, is a Person under Investigation, or has been Exposed to Ebola

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Offline: A pervasive failure to learn the lessons of Ebola

THE LANCET by Richard Horton                         Sept. 12, 2015

LONDON-- Post-Ebola reverie has given birth to a plethora of expert panels to consider what went wrong. The latest parade of global health specialists appointed to learn lessons gathered at the Wellcome Trust in London last week.
 Under the auspices of the US Institute of Medicine (IOM), a Commission to “deliberate and evaluate options to strengthen global, regional, and local systems to better prepare, detect, and respond to epidemic diseases” spent 2 days amassing evidence.

 There was no shortage of experience brought to bear on these important matters. Here were Margaret Chan, Jeremy Farrar, Ilona Kickbusch, David Heymann, Larry Gostin, Joy Phumaphi, Joanne Liu, and Peter Piot all wrestling with a seemingly intractable challenge. The statements offered to the Commission were arresting. But  the purpose of the meeting was not to talk. It was to identify the best system for an epidemic response....
Read complete article

http://www.thelancet.com/journals/lancet/article/PIIS0140-6736%2815%2900152-X/fulltext

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Grim Snapshot Reveals Complex Health Issues for Ebola Survivors [Infographic]

(CLICK ON IMAGE TO ENLARGE)

submitted by George Hurlburt

Sleeplessness, along with abdominal and joint pain are common even months after recovery from the dreaded virus

scientificamerican.com - by Dina Fine Maron - September 9, 2015

The first snapshot of health complications facing Ebola survivors in Sierra Leone presents a dismal picture of their road to recovery. A new study has found that up to four months after blood tests indicated that they were Ebola-free, more than half of survivors continue to suffer from joint pain, headaches or muscle pain. And more than 40 percent of survivors complain of sleeplessness and visual problems. Perhaps most worryingly, almost all the survivors—96 percent—reported being rejected by their communities after they were released from the hospital. The majority said they were still too scared to return home.

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WHO Vaccine-Preventable Diseases: Monitoring System - Country Summaries

                                       

apps.who.int

WHO Vaccine-Preventable Diseases: Monitoring System
(Click on the country of interest - then click "OK")
http://apps.who.int/immunization_monitoring/globalsummary

Country Summaries - WHO UNICEF Review of National Immunization Coverage, 1980-2014
(Click on the country of interest)
http://apps.who.int/immunization_monitoring/globalsummary/wucoveragecountrylist.html

 

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Ebola Outbreak Update - Sept. 8, 2015 - National Ebola Response Centre - Sierra Leone

submitted by Gavin Macgregor-Skinner

Ebola Outbreak update dated Sep 8 from the National Ebola Response Centre in Sierra Leone.

The four new Sierra Leone cases are in Sella Kaffta, a village in Kambia district in the northwest part of the country on Guinea's border. All the newly reported patients had contact with a 67-year-old woman whose death from Ebola was announced last week. After she died her body was washed before burial. There are 50 high-risk close contacts being monitored. Experimental ring vaccine campaign by WHO began Sep 4 and the newly diagnosed Ebola patients were not among the 116 people who received post-exposure VSV-EBOV vaccine.

Ebola Virus Disease (EVD) Update
http://health.gov.sl/?p=617

Ebola Virus Disease – Situation Report
http://health.gov.sl/?p=537

Ministry of Health and Sanitation - The Republic of Sierra Leone
http://health.gov.sl

National Ebola Response Centre (NERC) - Sierra Leone
http://www.nerc.sl

National Ebola Response Centre (NERC) - Sierra Leone - Evening Briefings
http://nerc.sl/?q=document-types/nerc-briefings

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