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Africa Resilience Initiative

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The mission of this working group is to articulate and shape issues of resilience and sustainability on the continent of Africa as they may be implemented as reforms of current policies, as well as contemplate and make recommendations for more extensive critiques and proposals for national, provincial, and local systems transformation, as may be necessary or desirable beyond the scope of traditional reforms being undertaken by the current African national governments and local government proposals in Africa.

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This working group is focused on developing an Africa Resilience Initiative to ensure resilience and sustainability for all Africans.
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Members

Aboubacar Conte admin Anthony bnorton Carrielaj Chisina Kapungu
ChrisAllen craig.sevcik Dr Ojia Adamolekun efrost Elhadj Drame Grace Kim
Hadiatou Balde jranck Kathy Gilbeaux mdmcdonald MDMcDonald_me_com mike kraft
njchapman Norea SmShako TacarraB Tjivekumba Kandjii

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Liberia’s Ebola Outbreak Largely Traced to One Source

            

BRANCHING OUT  In Liberia, a single lineage of Ebola virus (middle dot) split into subgroups as it passed from person to person and mutated. Each dot is a slightly different version of the virus within the subgroups. Dot size indicates how many people carried that version. Researchers tracked the virus as it spread from Liberia (blue) into Guinea (red) and Mali (yellow).  J.T. Ladner et al/Cell Host & Microbe 2015

CLICK HERE - STUDY - Evolution and Spread of Ebola Virus in Liberia, 2014–2015

Genetic analysis of third hard-hit country fills in gaps in virus’ spread and evolution

sciencenews.org - by Tina Hesman Saey - December 9, 2015

A single introduction of the Ebola virus led to most cases of the deadly disease in Liberia, a new genetic study suggests.

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Stopping Ebola in its Tracks: a Community-Led Response

reliefweb.int - globalcommunities.org - December 1, 2015

The public view of the Ebola response was dominated by images and stories of medical workers and Ebola treatment units. But there is also the less-known story of the many thousands of Liberian health workers, government staff, traditional leaders and volunteers who played the most significant role in building resilience to Ebola and reducing transmission and infection. It is these groups, working in the frontlines and at significant risk, which Global Communities partnered with throughout the Ebola response.

Global Communities’ approach to countering the Ebola outbreak has been highlighted by President Obama, Dr. Rajiv Shah, former Administrator of USAID, and many others as having been a key component in the successful fight against Ebola in Liberia in the 2014-15 outbreak. This new publication “Stopping Ebola in its Tracks,” has two strands:

It describes Global Communities’ community-driven response to the Ebola outbreak in Liberia

It derives from this experience lessons learned and recommendations for preventing and dealing with future disasters

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Disease Specialists Identify Post-Ebola Threats

             

The West Africa Ebola outbreak has led experts to consider what diseases might spark the next major infectious disease crisis. Waldo Swiegers/Bloomberg via Getty Images

Scientists to assemble a rogues’ gallery of viruses likely to spark the next international public-health crisis

nature.com - by Erika Check Hayden - December 7, 2015 - doi:10.1038/nature.2015.18952

As West Africans try to bring the calamitous Ebola outbreak to an end, the World Health Organization (WHO) has called scientists and doctors to Geneva, Switzerland, on 8 and 9 December to discuss which infectious disease is likely spark the next pandemic. . . 

. . . Nature canvassed infectious-disease specialists to find out which pathogens they thought would trigger the next global crisis, and which treatments and vaccines might be readied to combat them.

(READ COMPLETE ARTICLE)

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Vodafone Launches Mobile Cash Transfer System in Ghana Where 15M People Do Not Have a Bank Account

             

Moving money: The service, called M-Pesa, will be branded Vodafone Cash in the West African state

thisismoney.co.uk - by City & Finance Reporter for the Daily Mail - December 7, 2015

Vodafone has launched its mobile cash transfer system in Ghana where 15m people do not have a bank account.

The service, called M-Pesa, will be branded Vodafone Cash in the West African state. It allows mobile phone users to load money on to their phones, just as pay-as-you-go customers can top up their credit. 

They can send the funds anywhere in the country with a text message. Recipients can pick up the cash at shops that offer the service.

(READ COMPLETE ARTICLE)

 

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Mathematical Modeling of the West Africa Ebola Epidemic

eLife 2015;10.7554/eLife.09186 - December 8, 2015
DOI: http://dx.doi.org/10.7554/eLife.09186

Abstract

As of November 2015, the Ebola virus disease (EVD) epidemic that began in West Africa in late 2013 is waning. The human toll includes more than 28,000 Ebola virus disease (EVD) cases and 11,000 deaths in Guinea, Liberia, and Sierra Leone, the most heavily-affected countries. We reviewed 66 mathematical modeling studies of the EVD epidemic published in the peer-reviewed literature to assess the key uncertainties models addressed, data used for modeling, public sharing of data and results, and model performance. Based on the review, we suggest steps to improve the use of modeling in future public health emergencies.

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Identification of NPC1 as the Target of U18666A, an Inhibitor of Lysosomal Cholesterol Export and Ebola Infection

eLife 2015;10.7554/eLife.12177 - DECEMBER 8, 2015
DOI: http://dx.doi.org/10.7554/eLife.12177

Abstract

Niemann-Pick C1 (NPC1) is a lysosomal membrane protein that exports cholesterol derived from receptor-mediated uptake of LDL, and it also mediates cellular entry of Ebola virus. Cholesterol export is inhibited by nanomolar concentrations of U18666A, a cationic sterol. To identify the target of U18666A, we synthesized U-X, a U18666A derivative with a benzophenone that permits ultraviolet-induced crosslinking. When added to CHO cells, U-X crosslinked to NPC1. Crosslinking was blocked by U18666A derivatives that block cholesterol export, but not derivatives lacking blocking activity. Crosslinking was prevented by point mutation in the sterol-sensing domain (SSD) of NPC1, but not by point mutation in the N-terminal domain (NTD). These data suggest that the SSD contains a U18666A-inhibitable site required for cholesterol export distinct from the cholesterol-binding site in the NTD. Inasmuch as inhibition of Ebola requires 100-fold higher concentrations of U18666A, the high affinity U16888A-binding site is likely not required for virus entry. 

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At Climate Talks, African Nations Pledge to Restore Forests

         

FILE - In this Sunday, March 21, 2010 file photo, shafts of sunlight filtering through the forest canopy strike smoke from fires burning outside family huts at an Mbuti pygmy hunting camp in the Okapi Wildlife Reserve outside the town of Epulu, Congo. Tree by tree, more than a dozen African governments pledged to restore the continent’s natural forests at the U.N. climate change talks in Paris on Sunday, Dec. 6, 2015. (Rebecca Blackwell,File/Associated Press)

CLICK HERE - World Resources Institute - African Countries Launch AFR100 to Restore 100 Million Hectares of Land

CLICK HERE - African Forest Landscape Restoration Initiative (AFR100)

CLICK HERE - Global Landscapes Forum

washingtonpost.com - by Lynsey Chutel - December 6, 2015

JOHANNESBURG — Tree by tree, more than a dozen African governments pledged to restore the continent’s natural forests at the United Nations climate talks on Sunday.

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How Climate Change is Behind the Surge of Migrants to Europe

             

Migrants and refugees arrive on Sykamia beach, west of the port of Mytilene, on the Greek island of Lesbos after crossing the Aegean sea from Turkey, on Sept. 22, 2015.  Iakovos Hatzistavrou—AFP/Getty Images

Even as Europe wrestles over how to absorb the migrant tide, experts warn that the flood is likely to get worse as climate change becomes a driving factor.

time.com - by Aryn Baker - September 7, 2015

. . . “You think migration is a challenge to Europe today because of extremism, wait until you see what happens when there’s an absence of water, an absence of food, or one tribe fighting against another for mere survival,” . . .

. . . Security analysts say they are already seeing the impact, particularly in migration patterns from northern Africa and the Sahel region, which is the band of farmland just below the Sahara desert. “All the indicators seem to fairly solidly convey that climate change — desertification and lack of water, or floods, are massively contributing to human mobility . . .

(READ COMPLETE ARTICLE)

 
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Liberia: 'Blood Transfusion' - Responsible For New Ebola Outbreak

allafrica.com - November 27, 2015

Investigation conducted by this paper has established that unsafe blood transfusion is probably responsible for the new Ebola outbreak in Liberia.

A 15-year-old-boy was last weekend tested positive for Ebola and later pronounced dead on Tuesday. Dr. Francis Kateh, Chief Medical Officer of Liberia, said the boy's parents have also been tested positive for the virus and were undergoing observation.

The Ministry of Health and its partners are yet to disclose the source of the new outbreak, but a weeklong investigation conducted by this paper has established that blood recently transfused into the boy's mother at the Benson Hospital in Paynesville is the probable cause of the new Ebola infection.

(READ COMPLETE ARTICLE)

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