You are here

Africa Resilience Initiative

Primary tabs

The mission of this working group is to articulate and shape issues of resilience and sustainability on the continent of Africa as they may be implemented as reforms of current policies, as well as contemplate and make recommendations for more extensive critiques and proposals for national, provincial, and local systems transformation, as may be necessary or desirable beyond the scope of traditional reforms being undertaken by the current African national governments and local government proposals in Africa.

General Topic Tags: 
Problem, Solution, SitRep, or ?: 
Group description: 
This working group is focused on developing an Africa Resilience Initiative to ensure resilience and sustainability for all Africans.
Group roles and permissions: 
Use default roles and permissions
Group visibility: 
Public - accessible to all site users

Members

Aboubacar Conte admin Anthony bnorton Carrielaj Chisina Kapungu
ChrisAllen craig.sevcik Dr Ojia Adamolekun efrost Elhadj Drame Grace Kim
Hadiatou Balde jranck Kathy Gilbeaux mdmcdonald MDMcDonald_me_com mike kraft
njchapman Norea SmShako TacarraB Tjivekumba Kandjii

Email address for group

Ebola Virus Mutations May Help It Evade Drug Treatment

CLICK HERE - Ebola Virus Mutations May Help It Evade Drug Treatment (2 page .PDF file)

CLICK HERE - Cell Reports - Emergence of Ebola Virus Escape Variants in Infected Nonhuman Primates Treated with the MB-003 Antibody Cocktail

CLICK HERE - Emergence of Ebola Virus Escape Variants in Infected Nonhuman Primates Treated with the MB-003 Antibody Cocktail (11 page .PDF file)

usamriid.army.mil - September 11, 2015

Genetic mutations called “escape variants” in the deadly Ebola virus appear to block the ability of antibody-based treatments to ward off infection, according to a team of U.S. Army scientists and collaborators. Their findings, published online this week in the journal Cell Reports, have implications for the continued development of therapeutics to treat Ebola virus disease, which has claimed the lives of over 11,000 people in West Africa since last year.

General Topic Tags: 
Problem, Solution, SitRep, or ?: 

Ebola Assay Card | Elisa-Based Diagnostic - Google Science Fair

submitted by Gavin Macgregor-Skinner

Temperature-Independent, Portable, and Rapid Field Detection of Ebola via a Silk-Derived Lateral-Flow System

googlesciencefair.com - 2015

I developed a “stable and stored at room temperature” Ebola Assay Card, applicable as an ELISA-based diagnostic for diseases such as HIV, Lyme and certain cancers, that will allow for water-activated, timed-release detection of Ebola antigens, with detection limits that are analogous to current sandwich ELISA techniques. Reagents become chemically “stabilized” when mixed into silk, which enables them to remain “chemically active” without refrigeration. This Ebola Assay Card will allow for shipment and storage without refrigeration, and provide detection of the Ebola viral antigens based on color change in as little as 30 minutes.

(CLICK HERE FOR ADDITIONAL INFORMATION)

 

General Topic Tags: 
Problem, Solution, SitRep, or ?: 

Fighting Ebola With a Palm-Sized DNA Sequencer

submitted by George Hurlburt

      

Raymond Koundouno using a MinION - Sophie Duraffour

The MinION, a pocket-sized, USB-powered sequencing machine, lets scientists track the spread of deadly diseases in real-time.

theatlantic.com - by Ed Yong - September 16, 2015

. . . Unlike rival sequencers, which are as big as microwaves or fridges, the MinION is the size of a chocolate bar. . . . These devices quite literally bring the power of modern genomics to the palm of your hand. And at a cost of just $1,000, they herald a new era where sequencing moves away from well-equipped institutions and into places where it is most needed, from hospitals to epidemic-afflicted hot zones.

(READ COMPLETE ARTICLE)

(CLICK HERE - MinION - Oxford Nanopore Technologies)

(CLICK HERE - YouTube - MinION - Oxford Nanopore Technologies)

General Topic Tags: 
Problem, Solution, SitRep, or ?: 

Social Vulnerability and Ebola Virus Disease in Rural Liberia

      

Clusters of social vulnerability in rural Liberia, by district. Social vulnerability of each cluster of districts can be loosely ranked from most to least vulnerable as: Cluster 1, food quality, displaced persons, disabled, dependent populations; Cluster 3, food quantity, food quality, lack of access to land/free medical care; Cluster 4, food quantity, disabled dependent populations and Cluster 5, water quality/proximity to medical care; and finally, Cluster 2, no strong vulnerability scores.

CLICK HERE - Social Vulnerability and Ebola Virus Disease in Rural Liberia

CLICK HERE - Social Vulnerability and Ebola Virus Disease in Rural Liberia (14 page .PDF file)

srs.fs.usda.gov - by Zoe Hoyle - September 15, 2015

A newly published research study by U.S. Forest Service researchers demonstrates that the social vulnerability indices used in climate change and natural hazards research can also be used in other contexts such as disease outbreaks.

Country / Region Tags: 
Problem, Solution, SitRep, or ?: 

CDC - Care of a Neonate Born to a Mother who is Confirmed to have Ebola, is a Person under Investigation, or has been Exposed to Ebola

cdc.gov

Interim Guidance for U.S. Hospitals on the Care of a Neonate Born to a Mother who is Confirmed to have Ebola, is a Person under Investigation (PUI), or has been Exposed to Ebola

Who this is for: Healthcare professionals working with neonates in labor and delivery, neonatal intensive care units, newborn nurseries, and other settings in U.S. hospitals.

What this is for: Guidance on how to care for neonates born to mothers exposed to Ebola virus, PUIs, or with confirmed Ebola.

How to use this: This guidance is intended to help U.S. hospitals develop plans for treating neonates born to PUIs or to mothers with confirmed Ebola. Note: Ideally, these mothers and neonates will be cared for in Ebola assessment hospitals (if the mother is a PUI) or Ebola treatment centers (if the mother is confirmed to have Ebola.)1

CLICK HERE - Care of a Neonate Born to a Mother who is Confirmed to have Ebola, is a Person under Investigation, or has been Exposed to Ebola

General Topic Tags: 
Problem, Solution, SitRep, or ?: 

Offline: A pervasive failure to learn the lessons of Ebola

THE LANCET by Richard Horton                         Sept. 12, 2015

LONDON-- Post-Ebola reverie has given birth to a plethora of expert panels to consider what went wrong. The latest parade of global health specialists appointed to learn lessons gathered at the Wellcome Trust in London last week.
 Under the auspices of the US Institute of Medicine (IOM), a Commission to “deliberate and evaluate options to strengthen global, regional, and local systems to better prepare, detect, and respond to epidemic diseases” spent 2 days amassing evidence.

 There was no shortage of experience brought to bear on these important matters. Here were Margaret Chan, Jeremy Farrar, Ilona Kickbusch, David Heymann, Larry Gostin, Joy Phumaphi, Joanne Liu, and Peter Piot all wrestling with a seemingly intractable challenge. The statements offered to the Commission were arresting. But  the purpose of the meeting was not to talk. It was to identify the best system for an epidemic response....
Read complete article

http://www.thelancet.com/journals/lancet/article/PIIS0140-6736%2815%2900152-X/fulltext

Problem, Solution, SitRep, or ?: 

Grim Snapshot Reveals Complex Health Issues for Ebola Survivors [Infographic]

(CLICK ON IMAGE TO ENLARGE)

submitted by George Hurlburt

Sleeplessness, along with abdominal and joint pain are common even months after recovery from the dreaded virus

scientificamerican.com - by Dina Fine Maron - September 9, 2015

The first snapshot of health complications facing Ebola survivors in Sierra Leone presents a dismal picture of their road to recovery. A new study has found that up to four months after blood tests indicated that they were Ebola-free, more than half of survivors continue to suffer from joint pain, headaches or muscle pain. And more than 40 percent of survivors complain of sleeplessness and visual problems. Perhaps most worryingly, almost all the survivors—96 percent—reported being rejected by their communities after they were released from the hospital. The majority said they were still too scared to return home.

General Topic Tags: 
Problem, Solution, SitRep, or ?: 

WHO Vaccine-Preventable Diseases: Monitoring System - Country Summaries

                                       

apps.who.int

WHO Vaccine-Preventable Diseases: Monitoring System
(Click on the country of interest - then click "OK")
http://apps.who.int/immunization_monitoring/globalsummary

Country Summaries - WHO UNICEF Review of National Immunization Coverage, 1980-2014
(Click on the country of interest)
http://apps.who.int/immunization_monitoring/globalsummary/wucoveragecountrylist.html

 

General Topic Tags: 
Problem, Solution, SitRep, or ?: 

Ebola Outbreak Update - Sept. 8, 2015 - National Ebola Response Centre - Sierra Leone

submitted by Gavin Macgregor-Skinner

Ebola Outbreak update dated Sep 8 from the National Ebola Response Centre in Sierra Leone.

The four new Sierra Leone cases are in Sella Kaffta, a village in Kambia district in the northwest part of the country on Guinea's border. All the newly reported patients had contact with a 67-year-old woman whose death from Ebola was announced last week. After she died her body was washed before burial. There are 50 high-risk close contacts being monitored. Experimental ring vaccine campaign by WHO began Sep 4 and the newly diagnosed Ebola patients were not among the 116 people who received post-exposure VSV-EBOV vaccine.

Ebola Virus Disease (EVD) Update
http://health.gov.sl/?p=617

Ebola Virus Disease – Situation Report
http://health.gov.sl/?p=537

Ministry of Health and Sanitation - The Republic of Sierra Leone
http://health.gov.sl

National Ebola Response Centre (NERC) - Sierra Leone
http://www.nerc.sl

National Ebola Response Centre (NERC) - Sierra Leone - Evening Briefings
http://nerc.sl/?q=document-types/nerc-briefings

Country / Region Tags: 
General Topic Tags: 
Problem, Solution, SitRep, or ?: 

WHO - Polio Outbreak Confirmed in Mali

                                            

afro.who.int

Bamako, 7 September 2015 – A case of circulating vaccine-derived poliovirus type 2 (cVDPV2) has been confirmed in Bamako, the capital and largest city of Mali. The country is on high alert after national authorities detected a paralysis case with onset 20 July 2015. The patient is a 19-month old child of Guinean nationality whose paralysis occurred 7 days prior to the child’s arrival in Bamako to seek health care. The last case of wild polio virus (WPV) in Mali dates back to June 2011 in Goundam, Timbuktu Region.

The current detected virus is genetically linked to a confirmed VDPV detected in Siguiri district, in the Kankan Region of Guinea in August 2014, and has been circulating across international borders for more than 2 years without detection. 

The risk of spread of this virus is deemed high and it has the capacity to cause paralytic disease in humans or kill. The emergence and circulation of VDPV2 reveals low population immunity against the virus due to low rates of vaccination coverage in Guinea. Consequently, oral polio vaccine (OPV) must be administered multiple times to stop the outbreak and protect children. 

Country / Region Tags: 
General Topic Tags: 
Problem, Solution, SitRep, or ?: 

Pages

howdy folks
Page loaded in 0.844 seconds.