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Information on vaccines to counter Ebola and other diseases

The Mission of this group is to follow the development of vaccines and other medications to counter Ebola and other diseases.

Members

Kathy Gilbeaux mdmcdonald MDMcDonald_me_com mike kraft

Email address for group

vaccines_global@m.resiliencesystem.org

WHO - Ten Threats to Global Health in 2019

                                                

who.int

The world is facing multiple health challenges. These range from outbreaks of vaccine-preventable diseases like measles and diphtheria, increasing reports of drug-resistant pathogens, growing rates of obesity and physical inactivity to the  health impacts of environmental pollution and climate change and multiple humanitarian crises.   

To address these and other threats, 2019 sees the start of the World Health Organization’s new 5-year strategic plan – the 13th General Programme of Work. This plan focuses on a triple billion target:  ensuring 1 billion more people benefit from access to universal health coverage, 1 billion more people are protected from health emergencies and 1 billion more people enjoy better health and well-being. Reaching this goal will require addressing the threats to health from a variety of angles. 

Here are 10 of the many issues that will demand attention from WHO and health partners in 2019.

1.  Air pollution and climate change

2.  Noncommunicable diseases

3.  Global influenza pandemic

4.  Fragile and vulnerable settings

5.  Antimicrobial resistance

6.  Ebola and other high-threat pathogens

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Bharat Biotech Says Working on Two Possible Zika Vaccines

           

A municipal health worker shows off a test tube with larvae of Zika virus vector, the Aedes aegypti mosquito, as part of the city's efforts to prevent the spread of the Zika, in Guatemala City, Guatemala, February 2, 2016.  REUTERS/JOSUE DECAVELE

in.reuters.com - by ZEBA SIDDIQUI - February 3, 2016

Indian biotechnology company Bharat Biotech said on Wednesday it was working on two possible vaccines to fight the Zika virus, which has been linked to birth defects in thousands of babies in Brazil.

The virus is spreading rapidly in the Americas, and WHO officials on Tuesday expressed concern that it could hit Africa and Asia as well. No vaccine has been developed so far.

One of the possible vaccines is "recombinant", which means it is created by genetic engineering, while the other was "inactivated", and will enter pre-clinical trials in animals in two weeks, Bharat Biotech managing director Krishna Ella told Reuters.

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WHO To Vaccinate 200 Individuals Following Recent Sierra Leone Ebola Death

TECH TIMES by rina Maria Doctor     Sept. 3, 2015
The World Health Organization (WHO) is set to vaccinate about 200 people in Sierra Leone, who were believed to have been directly or indirectly exposed to a woman who succumbed to death due to the virus on Saturday, Aug. 29.

The 67-year-old woman, whose diagnostic test results came positive for Ebola, was a merchant from the Kambia District, which is close to the border of Guinea. She died five days after Sierra Leone has begun a countdown projected to last for 42 days before the country may be declared free from the deadly virus. Before her diagnosis, the last patient diagnosed with the disease was reported on Aug. 8....

WHO will immunize the people in the area of Tonko Limba who have had direct and indirect exposures to the deceased, says Margaret Harris, a spokesperson from WHO. This effort will also include people who have had close contacts with the said exposed individuals....

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How Will We Ensure the New Ebola Vaccine Reaches Those Most in Need?

HUFFINGTON POST  by Director of UNDP’s HIV, Health and Development Group, Bureau of Policy and Programme Support      Aug. 10, 2015                                                                 

 We have reasons to be optimistic about the news of a new tool in the fight against Ebola. As in the fight against HIV, science and solidarity have come together to save lives. The phase III trials on efficacy of the VSV-ZEBOV vaccine have yielded an impressive result in a relatively short time -- 100 percent effectiveness in those receiving the vaccine.

While scientists still need to figure out how long the protective effect of the vaccine lasts, and how effective it will be among the general population and with different strains of the virus, without a doubt this is an important tool for the protection of health and community workers and possibly the wider community. This will certainly help in the on-going efforts to achieve the target of zero new Ebola cases and in overall recovery efforts.

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Physicians: Global Vaccine Development Fund Could Save Billions

PHARMACEUTICAL PROCESSING by  Princeton University, Woodrow Wilson School of Public and International Affairs   Aug. 6, 2015

Ebola is a preventable disease, and yet a safe and effective vaccine has not been deployed. As with many vaccines, financial barriers persist: pharmaceutical companies see high costs with limited market potential, and government support is lacking. But there may be a solution to this vaccine crisis with the ability to save at-risk populations, according to a perspective piece written by physicians based at Princeton University, University of Pennsylvania and the Wellcome Trust.

The article, published in the New England Journal of Medicine, proposes the creation of a $2 billion global vaccine-development fund - supported by governments, foundations and pharmaceutical companies - that would carry promising vaccines through development to deployment. With initial support, the global vaccine fund could help make vaccines available for emergency use.

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