BUSINESS STANDARD                                                                        April 27, 2015

HYDERABAD, India --Ella Foundation, which has taken up research for finding a potential vaccine for the deadly Ebola virus, today said it had successfully completed preliminary studies on the virus, which was responsible for high fatalities among humans in central Africa.

The Hyderabad-based foundation said it had completed the preliminary animal (with mice) experiments of the virus' glycoprotein with the targeted adenovirus, and the "immune response results have been good", which would be followed by toxicology tests and the subsequent clinical trials involving human beings.

Adenoviruses are responsible for respiratory infections, gastroenteritis, cystitis, and primary pneumonia in humans, and are therefore used as a clear target to understand the human immunity characteristics in laboratory. However, the efficacy of the vaccine is judged by the outcomes seen in human trials.

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http://www.business-standard.com/article/current-affairs/ella-foundation-announces-key-outcomes-in-ebola-vaccine-research-115042700631_1.html

UPDATE with testimony to Congress.

Obama says Ebola-fighting goal is to prevent any new cases

(Scroll down for earlier story and link to Congressional testimony by administration officials)

ASSOCIATED PRESS       by Jim Kuhnhenn                                              APRIL 15.                                    

WASHINGTON — Citing significant gains in fighting the Ebola outbreak in West Africa, President Obama declared Wednesday that the international goal now is to prevent any new cases of the deadly virus in the afflicted region....

President Barack Obama and Vice President Joe Biden, back right, meets with, from left, Sierra Leone President Ernest Bai Koroma, Liberian President Ellen Johnson Sirleaf, and Guinean President Alpha Condé, in the Cabinet Room of the White House in Washington, Wednesday, April 15, 2015, to discuss progress made in the international Ebola response. (Manuel Balce Ceneta/Associated Press)

USA TODAY by Liz Szabo                                                                 April 14, 2015
Sierra Leone has begun testing an experimental Ebola vaccine, officials of the Centers for Disease Control and Prevention announced Tuesday.
                                                                                            (Photo: CELLOU BINANI, AFP/Getty Images)

The $25 million study, funded through $5.4 billion in Ebola aid authorized by Congress, will test vaccines on 6,000 "front-line workers," including doctors, nurses, burial workers and others, who are at highest risk of the disease.

But with only a handful of new Ebola cases being reported now in Sierra Leone, it may be difficult to get a clear answer on whether the vaccine actually works, the CDC acknowledges. If there are no new cases of Ebola among vaccinated volunteers, for example, researchers won't know if that's the result of the immunizations or because the outbreak has faded....

INQUIRER.NET  by Kristine Angeli Sabillo                  APRIL 8, 2015

MANILA --As the Ebola outbreak in West Africa winds down, the United Nations is optimistic that a vaccine against the deadly virus will be made available in the next several months.

“Clinical trials have have now been undertaken of candidate vaccines, two of them. They are now at an advanced stage,” Dr. David Nabarro, UN secretary general special envoy on Ebola, told reporters in Manila on Wednesday.

“I believe that we will have a vaccine against Ebola that is available and can be used particularly for doctors and nurses who provide treatment for people with the disease in the coming months,” he added.

According to the World Health Organization, the two vaccine candidates undergoing efficacy trials are ChAd3-ZEBOV, developed by GlaxoSmithKline (GSK), and rVSV-ZEBOV, developed by NewLink Genetics and Merck Vaccines USA. The first is being developed in collaboration with the US National Institute of Allergy and Infectious Diseases (NIAID) and the second with the Public Health Agency of Canada.

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http://globalnation.inquirer.net/120463/un-envoy-expect-ebola-vaccine-in-coming-months/