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SES joins consortium to fight Ebola with mobile lab

BIOPREPWATCH   by Shaun Zinck                                                 Dec. 26, 2014

SES, a satellite communications company, announced on Monday that it was teaming up with a collaborative group that runs a mobile laboratory to improve response time in the fight against the Ebola virus.

B-LiFE, a mobile laboratory, is run through a consortium between the public, private and academic sectors in Belgium. The group is trying to increase identification of diseases for a quicker response to crisis situations such as the Ebola epidemic.

“B-LiFE demonstrates the relevance of satellite for medical purposes,” Gerhard Bethscheider, managing director of SES TechCom, said. ...It is anticipated that the lab, which left Belgium on Saturday, will be stationed at an Ebola treatment center in Guinea that was set up by ALIMA, a French non-government organization

http://bioprepwatch.com/news/ses-joins-consortium-to-fight-ebola-with-mobile-lab/340396/

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Ebola death toll rises to 7,588 globally, WHO says

AFP                                                                                         Dec. 26, 2014

The global death toll from Ebola has risen to 7,588 out of 19,497 confirmed cases recorded in the year-old epidemic raging in West Africa, the World Health Organization (WHO) says.

The virus is still spreading intensely in Sierra Leone, especially in the north and west, with 315 new confirmed cases reported in the former British colony in the week to December 21, it said. These included 115 cases in the capital Freetown.

"The neighbouring district of Port Loko experienced a surge in new cases, reporting 92 confirmed cases compared with 56 the previous week," the WHO said.

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http://www.cbc.ca/news/business/ebola-death-toll-rises-to-7-588-globally-who-says-1.2884197

Read  Full WHO report
http://www.who.int/csr/disease/ebola/situation-reports/en/

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UK must act to guard against pandemics, says scientist who discovered Ebola virus

THE INDEPENDENT by Charlie Cooper                                                               Dec. 26, 2014

The UK must create a new health security agency to guard against future pandemics, according to the scientist who discovered the Ebola virus. Professor Peter Piot said Britain and Europe lacked “an epidemic intelligence service” with global reach, leaving them “vulnerable” and less able to intervene in overseas health crises such as the Ebola outbreak, which has killed thousands of people in West Africa. Peter Piot discovered Ebola when he was sent to investigate an outbreak in Zaire, now the DRC, in 1976 (AFP/Getty)

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Next in Ebola Plan: UN Teams to Study Lines of Transmission

REUTERS                                                              Dec. 24, 2014

ACCRA—Medical detective work will be the next big phase in the fight against Ebola when the United Nations deploys hundreds of health workers to identify chains of infection as the virus passes from person to person, top U.N. health workers said.
Health workers bury the body of a suspected Ebola victim at a cemetery in Freetown, Dec. 21, 2014.

The health teams will travel to each district and region of Guinea, Sierra Leone and Liberia, the three countries at the center of the epidemic, to trace who each infected person has potentially contacted.

The effort will run in parallel with measures to minimize the spread of infection, such as treating all Ebola patients in specialized centers and burying all victims safely.

But Phase Two of the plan is to contain the virus by understanding its lines of transmission, said World Health Organization Director-General Margaret Chan.

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Ebola crisis likely to last a year, says expert

BBC                                             Dec. 24, 2014       

West Africa's Ebola crisis is likely to last until the end of 2015, says a leading researcher who helped to discover the virus.

Peter Piot, who has just returned from Sierra Leone, told the BBC that he was encouraged by progress there and by the promise of new anti-viral therapies.

But he also warned that vaccines would take time to develop....

Prof Piot was one of the scientists who discovered Ebola in 1976and is now Director of the London School of Hygiene and Tropical Medicine.

He said that even though the outbreak has peaked in Liberia and was likely to peak in Sierra Leone in the next few weeks, the epidemic could have a "very long tail and a bumpy tail"...

"We need to be ready for a long effort, a sustained effort [for] probably the rest of 2015."

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http://www.bbc.com/news/world-africa-30595352

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Ebola in the 'red zone'

REUTERS    by Emma Farge                                            Dec. 23, 2014

HASTINGS, Sierra Leone-- When Dr Sekou Kanneh goes to work at his Sierra Leonean Ebola clinic, he will probably be in the "red zone" for many hours, ignoring by necessity strict limits that govern foreign colleagues fighting the epidemic.

Doctor Sekou Kanneh speaks during an interview with Reuters TV in the Hastings ebola treatment centre at a neighbourhood in Freetown, December 21, 2014. Credit: Reuters/Baz Ratner 

Conditions at Kanneh's treatment center, the only Ebola unit in the country run by local staff, contrast to the purpose-built facilities where foreign volunteers who have flocked to Sierra Leone, Guinea and Liberia work.

Kanneh has received no official training to treat the virus that has killed over 7,000 people in West Africa. Still, he works up to four hour shifts in the stifling heat of the red zone, a ward where healthcare workers have direct contact with the highly contagious Ebola patients.

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Evaluation of the Benefits and Risks of Introducing Ebola Community Care Centers, Sierra Leone

     

CDC                                                                                                         Dec. 23, 2014    

Abstract of study on usefulness of Ebola community care centers to supplement larger  Ebola treatment centers.

 In some parts of western Africa, Ebola treatment centers (ETCs) have reached capacity. Unless capacity is rapidly scaled up, the chance to avoid a generalized Ebola epidemic will soon diminish. The World Health Organization and partners are considering additional Ebola patient care options, including community care centers (CCCs), small, lightly staffed units that could be used to isolate patients outside the home and get them into care sooner than otherwise possible.

Using a transmission model, we evaluated the benefits and risks of introducing CCCs into Sierra Leone’s Western Area, where most ETCs are at capacity. We found that use of CCCs could lead to a decline in cases, even if virus transmission occurs between CCC patients and the community. However, to prevent CCC amplification of the epidemic, the risk of Ebola virus–negative persons being exposed to virus within CCCs would have to be offset by a reduction in community transmission resulting from CCC use.

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Ebola raises profile of blood-based therapy

NATURE     by  Delcan Butler                                                                                        Dec. 23, 2014

With no drugs available to treat Ebola, eyes are turning to a therapy that had largely been relegated to the history books: transfusing patients with blood plasma donated by survivors, which contains antibodies against the virus.

Survivors of Ebola carry antibodies that might be used to save the lives of those infected with the virus. Michel du Cille/The Washington Post via Getty Images

Clinical trials of convalescent plasma therapy (CPT) have started in the past few weeks in Liberia, and are due to begin soon in Guinea and Sierra Leone. If the therapy saves lives, the approach could quickly be scaled up.

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C.D.C. Head Says Fight on Ebola Will Be Long

NEW YORK TIMES by Denise Grady                             Dec. 23, 2014
There are reasons for both hope and continued worry about the Ebola epidemic in West Africa, Dr. Thomas R. Frieden, director of the Centers for Disease Control and Prevention, said on Monday.

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Ebola vaccine 'promising in African populations'

BBC     By Smitha Mundasad                                Dec. 22, 2014
The first-ever trial of an Ebola vaccine in Africa shows promising initial results, according to a report in the Lancet medical journal.

Scientists say it is a crucial step as other vaccines have shown lower levels of protection in African populations.

Tests involving Ugandan and American volunteers reveal the vaccine is so far safe and generates an immune response in both populations.

It provides reassurance for other trials currently underway, they say.

No proven vaccine exists to prevent people from getting the disease, though several trials are underway.

Researchers from the National Institutes of Health tested this experimental vaccine on healthy adults in Uganda, having first trialled it in the United States.

Dr Julie Ledgerwood, the lead researcher, said: "This is the first study to show comparable safety and immune response of an experimental Ebola vaccine in an African population.

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http://www.bbc.com/news/health-30577776

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